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Chemistry

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Also known as: 1307245-86-8, Ly-2940094, Ly2940094, Btrx-246040, Ly 2940094 - bio-x, (2-(4-((2'-chloro-4',4'-difluoro-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]-1-yl)methyl)-3-methyl-1h-pyrazol-1-yl)pyridin-3-yl)methanol
Molecular Formula
C22H23ClF2N4O2S
Molecular Weight
481.0  g/mol
InChI Key
NKQHBJNRBKHUQR-UHFFFAOYSA-N
FDA UNII
4I67US2V8Q

LY-2940094
BTRX-246040 is under investigation in clinical trial NCT03193398 (BTRX-246040 Administered Once Daily to Patients With Major Depressive Disorder).
1 2D Structure

LY-2940094

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[2-[4-[(2-chloro-4,4-difluorospiro[5H-thieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)methyl]-3-methylpyrazol-1-yl]pyridin-3-yl]methanol
2.1.2 InChI
InChI=1S/C22H23ClF2N4O2S/c1-14-16(11-29(27-14)20-15(12-30)3-2-6-26-20)10-28-7-4-21(5-8-28)19-17(9-18(23)32-19)22(24,25)13-31-21/h2-3,6,9,11,30H,4-5,7-8,10,12-13H2,1H3
2.1.3 InChI Key
NKQHBJNRBKHUQR-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=NN(C=C1CN2CCC3(CC2)C4=C(C=C(S4)Cl)C(CO3)(F)F)C5=C(C=CC=N5)CO
2.2 Other Identifiers
2.2.1 UNII
4I67US2V8Q
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(4-((2-chloro-4,4-difluorospiro(5h-thieno(2,3-c)pyran-7,4'-piperidine)-1'-yl)methyl)-3-methylpyrazol-1-yl)-3-pyridyl)methanol

2. Ly2940094

2.3.2 Depositor-Supplied Synonyms

1. 1307245-86-8

2. Ly-2940094

3. Ly2940094

4. Btrx-246040

5. Ly 2940094 - Bio-x

6. (2-(4-((2'-chloro-4',4'-difluoro-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]-1-yl)methyl)-3-methyl-1h-pyrazol-1-yl)pyridin-3-yl)methanol

7. 4i67us2v8q

8. J3.309.394b

9. 1307245-86-8 (free Base)

10. [2-[4-[(2-chloro-4,4-difluorospiro[5h-thieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)methyl]-3-methylpyrazol-1-yl]pyridin-3-yl]methanol

11. 2-(3-methyl-4-((2-chloro-4,4-difluorospiro(5h-thieno(2,3-c)pyran-7,4'-piperidine)-1'-yl)methyl)-1h-pyrazole-1-yl)pyridine-3-methanol

12. [2-[4-[(2-chloro-4,4-difluoro-spiro[5h-thieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)methyl]-3-methyl-pyrazol-1-yl]-3-pyridyl]methanol

13. 2-[3-methyl-4-[(2-chloro-4,4-difluorospiro[5h-thieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)methyl]-1h-pyrazole-1-yl]pyridine-3-methanol

14. Unii-4i67us2v8q

15. Gtpl9462

16. Schembl1807310

17. Schembl1809717

18. Chembl3304244

19. Dtxsid201336137

20. Bcp30786

21. Ex-a3004

22. Sb19609

23. Compound 36 [pmid: 24678969]

24. Ac-36290

25. Hy-114452

26. Cs-0085528

27. E74551

28. Ly 2940094; Ly2940094

29. [2-[4-[(2-chloro-4,4-difluoro-spiro[5hthieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)methyl]-3-methyl-pyrazol-1-yl]-3-pyridyl]methanol

2.4 Create Date
2011-05-31
3 Chemical and Physical Properties
Molecular Weight 481.0 g/mol
Molecular Formula C22H23ClF2N4O2S
XLogP33.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count4
Exact Mass480.1198312 g/mol
Monoisotopic Mass480.1198312 g/mol
Topological Polar Surface Area91.6 Ų
Heavy Atom Count32
Formal Charge0
Complexity672
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Looking for 1307245-86-8 / LY-2940094 API manufacturers, exporters & distributors?

LY-2940094 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of LY-2940094 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right LY-2940094 manufacturer or LY-2940094 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred LY-2940094 manufacturer or LY-2940094 supplier.

PharmaCompass also assists you with knowing the LY-2940094 API Price utilized in the formulation of products. LY-2940094 API Price is not always fixed or binding as the LY-2940094 Price is obtained through a variety of data sources. The LY-2940094 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

LY-2940094

Synonyms

1307245-86-8, Ly2940094, Btrx-246040, Ly 2940094 - bio-x, (2-(4-((2'-chloro-4',4'-difluoro-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]-1-yl)methyl)-3-methyl-1h-pyrazol-1-yl)pyridin-3-yl)methanol, 4i67us2v8q

Cas Number

1307245-86-8

Unique Ingredient Identifier (UNII)

4I67US2V8Q

About LY-2940094

BTRX-246040 is under investigation in clinical trial NCT03193398 (BTRX-246040 Administered Once Daily to Patients With Major Depressive Disorder).

LY-2940094 Manufacturers

A LY-2940094 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of LY-2940094, including repackagers and relabelers. The FDA regulates LY-2940094 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. LY-2940094 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

LY-2940094 Suppliers

A LY-2940094 supplier is an individual or a company that provides LY-2940094 active pharmaceutical ingredient (API) or LY-2940094 finished formulations upon request. The LY-2940094 suppliers may include LY-2940094 API manufacturers, exporters, distributors and traders.

LY-2940094 GMP

LY-2940094 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of LY-2940094 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right LY-2940094 GMP manufacturer or LY-2940094 GMP API supplier for your needs.

LY-2940094 CoA

A LY-2940094 CoA (Certificate of Analysis) is a formal document that attests to LY-2940094's compliance with LY-2940094 specifications and serves as a tool for batch-level quality control.

LY-2940094 CoA mostly includes findings from lab analyses of a specific batch. For each LY-2940094 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

LY-2940094 may be tested according to a variety of international standards, such as European Pharmacopoeia (LY-2940094 EP), LY-2940094 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (LY-2940094 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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