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Chemistry

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Also known as: 52214-84-3, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid, Lipanor, Ciprofibratum, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid, Ciprofibrato
Molecular Formula
C13H14Cl2O3
Molecular Weight
289.15  g/mol
InChI Key
KPSRODZRAIWAKH-UHFFFAOYSA-N
FDA UNII
F8252JGO9S

Ciprofibrate
Ciprofibrate is a fibrate derivative with antilipidemic activity.
1 2D Structure

Ciprofibrate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
2.1.2 InChI
InChI=1S/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)
2.1.3 InChI Key
KPSRODZRAIWAKH-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(C)(C(=O)O)OC1=CC=C(C=C1)C2CC2(Cl)Cl
2.2 Other Identifiers
2.2.1 UNII
F8252JGO9S
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Hyperlipen

2. Lipanor

3. Modalim

4. Oroxadin

5. Win 35,833

2.3.2 Depositor-Supplied Synonyms

1. 52214-84-3

2. 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropanoic Acid

3. Lipanor

4. Ciprofibratum

5. 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic Acid

6. Ciprofibrato

7. Modalim

8. Win 35833

9. Win-35833

10. Propanoic Acid, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl-

11. Mfcd00467135

12. 2-(p-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropionic Acid

13. Nsc-759617

14. F8252jgo9s

15. Chebi:50867

16. Propanoic Acid, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-

17. Ncgc00164447-01

18. 2-{[4-(2,2-dichlorocyclopropyl)phenyl]oxy}-2-methylpropanoic Acid

19. Dsstox_cid_331

20. Dsstox_rid_75519

21. Dsstox_gsid_20331

22. Ciprofibratum [inn-latin]

23. Ciprofibrato [inn-spanish]

24. Hiperlipen

25. Ciprol

26. Smr000857190

27. Ccris 173

28. Sr-01000075734

29. Einecs 257-744-6

30. Ciprofibrate (usan/inn)

31. Brn 1984981

32. Unii-f8252jgo9s

33. 2-[p-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropionic Acid

34. Ciprofibrate?

35. Ciprofibrate [usan:inn:ban]

36. 2-(4-(2,2-dichlorocyclopropyl)phenoxy)2-methylpropanoic Acid

37. 2-[p-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic Acid

38. Cas-52214-84-3

39. Ciprofibrate- Bio-x

40. Prestwick0_001076

41. Prestwick1_001076

42. Prestwick2_001076

43. Prestwick3_001076

44. Ciprofibrate [mi]

45. Ciprofibrate [inn]

46. C 0330

47. Ciprofibrate [usan]

48. Lopac0_000168

49. Schembl26870

50. Bspbio_001092

51. Ciprofibrate [mart.]

52. Mls002154143

53. Mls006011758

54. Ciprofibrate [who-dd]

55. Win35833

56. Spbio_002996

57. Bpbio1_001202

58. Chembl557555

59. Gtpl3438

60. Dtxsid8020331

61. Bcpp000277

62. Ciprofibrate [ep Impurity]

63. Ciprofibrate For System Suitability

64. Hms1571g14

65. Hms2098g14

66. Hms2235j14

67. Hms3260b17

68. Hms3369b22

69. Hms3656p09

70. Hms3715g14

71. Pharmakon1600-01502008

72. Ciprofibrate [ep Monograph]

73. Bcp03728

74. Hy-b0664

75. Tox21_112121

76. Tox21_201359

77. Tox21_302840

78. Tox21_500168

79. Bbl010821

80. Bdbm50371235

81. Nsc759617

82. S2665

83. Stk624758

84. Akos005557843

85. Tox21_112121_1

86. Ac-1018

87. Bcp9000533

88. Ccg-204263

89. Db09064

90. Ks-1201

91. Lp00168

92. Nsc 759617

93. Sdccgsbi-0050156.p002

94. Ncgc00015202-02

95. Ncgc00015202-03

96. Ncgc00015202-04

97. Ncgc00015202-05

98. Ncgc00015202-06

99. Ncgc00015202-08

100. Ncgc00015202-20

101. Ncgc00015202-21

102. Ncgc00093652-01

103. Ncgc00093652-02

104. Ncgc00256361-01

105. Ncgc00258911-01

106. Ncgc00260853-01

107. Bd164311

108. Bcp0726000148

109. Ab00514032

110. Eu-0100168

111. Ft-0602946

112. Sw197242-4

113. D03521

114. O10468

115. Ab00514032_06

116. 214c843

117. A828985

118. J-520054

119. Q3496452

120. Sr-01000075734-1

121. Sr-01000075734-4

122. Sr-01000075734-7

123. Brd-a49358627-001-03-9

124. Brd-a49358627-001-10-4

125. 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropionic Acid

126. Ciprofibrate, European Pharmacopoeia (ep) Reference Standard

127. 2-[4-[2,2-bis(chloranyl)cyclopropyl]phenoxy]-2-methyl-propanoic Acid

128. Ciprofibrate For System Suitability, European Pharmacopoeia (ep) Reference Standard

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 289.15 g/mol
Molecular Formula C13H14Cl2O3
XLogP33.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass288.0319997 g/mol
Monoisotopic Mass288.0319997 g/mol
Topological Polar Surface Area46.5 Ų
Heavy Atom Count18
Formal Charge0
Complexity333
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Peroxisome Proliferators

A class of nongenotoxic CARCINOGENS that induce the production of hepatic PEROXISOMES and induce hepatic neoplasms after long-term administration. (See all compounds classified as Peroxisome Proliferators.)


Hypolipidemic Agents

Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS. (See all compounds classified as Hypolipidemic Agents.)


4.2 ATC Code

C10AB08

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355


C - Cardiovascular system

C10 - Lipid modifying agents

C10A - Lipid modifying agents, plain

C10AB - Fibrates

C10AB08 - Ciprofibrate


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ABOUT THIS PAGE

Looking for 52214-84-3 / Ciprofibrate API manufacturers, exporters & distributors?

Ciprofibrate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Ciprofibrate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ciprofibrate manufacturer or Ciprofibrate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ciprofibrate manufacturer or Ciprofibrate supplier.

PharmaCompass also assists you with knowing the Ciprofibrate API Price utilized in the formulation of products. Ciprofibrate API Price is not always fixed or binding as the Ciprofibrate Price is obtained through a variety of data sources. The Ciprofibrate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Ciprofibrate

Synonyms

52214-84-3, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid, Lipanor, Ciprofibratum, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid, Ciprofibrato

Cas Number

52214-84-3

Unique Ingredient Identifier (UNII)

F8252JGO9S

About Ciprofibrate

Ciprofibrate is a fibrate derivative with antilipidemic activity.

Lipanor Manufacturers

A Lipanor manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Lipanor, including repackagers and relabelers. The FDA regulates Lipanor manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Lipanor API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Lipanor manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Lipanor Suppliers

A Lipanor supplier is an individual or a company that provides Lipanor active pharmaceutical ingredient (API) or Lipanor finished formulations upon request. The Lipanor suppliers may include Lipanor API manufacturers, exporters, distributors and traders.

click here to find a list of Lipanor suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Lipanor CEP

A Lipanor CEP of the European Pharmacopoeia monograph is often referred to as a Lipanor Certificate of Suitability (COS). The purpose of a Lipanor CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Lipanor EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Lipanor to their clients by showing that a Lipanor CEP has been issued for it. The manufacturer submits a Lipanor CEP (COS) as part of the market authorization procedure, and it takes on the role of a Lipanor CEP holder for the record. Additionally, the data presented in the Lipanor CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Lipanor DMF.

A Lipanor CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Lipanor CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Lipanor suppliers with CEP (COS) on PharmaCompass.

Lipanor WC

A Lipanor written confirmation (Lipanor WC) is an official document issued by a regulatory agency to a Lipanor manufacturer, verifying that the manufacturing facility of a Lipanor active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Lipanor APIs or Lipanor finished pharmaceutical products to another nation, regulatory agencies frequently require a Lipanor WC (written confirmation) as part of the regulatory process.

click here to find a list of Lipanor suppliers with Written Confirmation (WC) on PharmaCompass.

Lipanor GMP

Lipanor Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Lipanor GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Lipanor GMP manufacturer or Lipanor GMP API supplier for your needs.

Lipanor CoA

A Lipanor CoA (Certificate of Analysis) is a formal document that attests to Lipanor's compliance with Lipanor specifications and serves as a tool for batch-level quality control.

Lipanor CoA mostly includes findings from lab analyses of a specific batch. For each Lipanor CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Lipanor may be tested according to a variety of international standards, such as European Pharmacopoeia (Lipanor EP), Lipanor JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Lipanor USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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