Find INX-315 manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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API Suppliers

API Suppliers

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

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Listed Suppliers

Other Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

FINISHED DOSAGE FORMULATIONS

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FDA Orange Book

FDA (Orange Book)

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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DRUG PRODUCT COMPOSITIONS

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0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

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US Patents

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US Exclusivities

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Health Canada Patents

API REF. PRICE (USD/KG)

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GLOBAL SALES INFORMATION

US Medicaid

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Annual Reports

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Chemistry

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Also known as: Inx-315, 2745060-92-6, Inx315, Schembl24052539, Us11643416, compound 3, Bdbm601935
Molecular Formula
C19H21N7O3S
Molecular Weight
427.5  g/mol
InChI Key
KGJVKYSVVOQPDL-UHFFFAOYSA-N
FDA UNII
2QD8YT8RWZ

INX-315
CDK2 Inhibitor INX-315 is an orally bioavailable small molecule inhibitor of cyclin-dependent kinase 2 (CDK2), with potential antineoplastic activity. Upon oral administration, CDK2 inhibitor INX-315 selectively targets, binds to and inhibits the activity of CDK2. This may lead to cell cycle arrest, the induction of apoptosis, and the inhibition of tumor cell proliferation. CDKs are serine/threonine kinases that are important regulators of cell cycle progression and cellular proliferation and are frequently overexpressed in tumor cells.
1 2D Structure

INX-315

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[(12-oxospiro[1,3,5,10,11-pentazatricyclo[7.4.0.02,7]trideca-2,4,6,8-tetraene-13,1'-cyclohexane]-4-yl)amino]benzenesulfonamide
2.1.2 InChI
InChI=1S/C19H21N7O3S/c20-30(28,29)14-6-4-13(5-7-14)22-18-21-11-12-10-15-24-25-17(27)19(8-2-1-3-9-19)26(15)16(12)23-18/h4-7,10-11,24H,1-3,8-9H2,(H,25,27)(H2,20,28,29)(H,21,22,23)
2.1.3 InChI Key
KGJVKYSVVOQPDL-UHFFFAOYSA-N
2.2 Other Identifiers
2.2.1 UNII
2QD8YT8RWZ
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Inx-315

2. 2745060-92-6

3. Inx315

4. Schembl24052539

5. Us11643416, Compound 3

6. Bdbm601935

7. Ex-a8446

8. Inx-315?

9. Hy-162001

10. Cs-0909828

11. 4-((3'-oxo-2',3'-dihydro-1'h- Spiro[cyclohexane-1,4'- Pyrimido[5',4':4,5]pyrrolo[2,1- C][1,2,4]triazin]-7'- Yl)amino)benzenesulfonamide

2.4 Create Date
2021-12-13
3 Chemical and Physical Properties
Molecular Weight 427.5 g/mol
Molecular Formula C19H21N7O3S
XLogP32.4
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count8
Rotatable Bond Count3
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area152
Heavy Atom Count30
Formal Charge0
Complexity759
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 2745060-92-6 / INX-315 API manufacturers, exporters & distributors?

INX-315 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of INX-315 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right INX-315 manufacturer or INX-315 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred INX-315 manufacturer or INX-315 supplier.

PharmaCompass also assists you with knowing the INX-315 API Price utilized in the formulation of products. INX-315 API Price is not always fixed or binding as the INX-315 Price is obtained through a variety of data sources. The INX-315 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

INX-315

Synonyms

2745060-92-6, Inx315, Schembl24052539, Us11643416, compound 3, Bdbm601935, Ex-a8446

Cas Number

2745060-92-6

Unique Ingredient Identifier (UNII)

2QD8YT8RWZ

About INX-315

CDK2 Inhibitor INX-315 is an orally bioavailable small molecule inhibitor of cyclin-dependent kinase 2 (CDK2), with potential antineoplastic activity. Upon oral administration, CDK2 inhibitor INX-315 selectively targets, binds to and inhibits the activity of CDK2. This may lead to cell cycle arrest, the induction of apoptosis, and the inhibition of tumor cell proliferation. CDKs are serine/threonine kinases that are important regulators of cell cycle progression and cellular proliferation and are frequently overexpressed in tumor cells.

INX-315 Manufacturers

A INX-315 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of INX-315, including repackagers and relabelers. The FDA regulates INX-315 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. INX-315 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

INX-315 Suppliers

A INX-315 supplier is an individual or a company that provides INX-315 active pharmaceutical ingredient (API) or INX-315 finished formulations upon request. The INX-315 suppliers may include INX-315 API manufacturers, exporters, distributors and traders.

INX-315 GMP

INX-315 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of INX-315 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right INX-315 GMP manufacturer or INX-315 GMP API supplier for your needs.

INX-315 CoA

A INX-315 CoA (Certificate of Analysis) is a formal document that attests to INX-315's compliance with INX-315 specifications and serves as a tool for batch-level quality control.

INX-315 CoA mostly includes findings from lab analyses of a specific batch. For each INX-315 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

INX-315 may be tested according to a variety of international standards, such as European Pharmacopoeia (INX-315 EP), INX-315 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (INX-315 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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