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06-Jan-2025
21-May-2025
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Drugs in Development

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Details:

Inclisiran is a Oligonucleotide drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Acute Coronary Syndrome.


Lead Product(s): Inclisiran,Inapplicable

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Oligonucleotide

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable August 04, 2025

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01

VMX
Not Confirmed
VMX
Not Confirmed

Details : Inclisiran is a Oligonucleotide drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Acute Coronary Syndrome.

Product Name : Undisclosed

Product Type : Oligonucleotide

Upfront Cash : Inapplicable

August 04, 2025

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Details:

Leqvio (inclisiran) is a siRNA directed to PCSK9 mRNA indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of heterozygous familial hypercholesterolemia.


Lead Product(s): Inclisiran,Inapplicable

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Leqvio

Study Phase: Approved FDFProduct Type: Oligonucleotide

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable July 31, 2025

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02

VMX
Not Confirmed
VMX
Not Confirmed

Details : Leqvio (inclisiran) is a siRNA directed to PCSK9 mRNA indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of heterozygous familial hypercholesterolemia.

Product Name : Leqvio

Product Type : Oligonucleotide

Upfront Cash : Inapplicable

July 31, 2025

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  • Development Update

Details:

Inclisiran Sodium is a Oligonucleotide drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of undefined medical condition.


Lead Product(s): Inclisiran Sodium,Inclisiran

Therapeutic Area: Undisclosed Brand Name: Undisclosed

Study Phase: Phase IVProduct Type: Oligonucleotide

Sponsor: Novartis Pharmaceuticals Corporation | Colorado Prevention Center | Mount Sinai Hospital, New York

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable April 03, 2025

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03

Duke University

Country
arrow
VMX
Not Confirmed

Duke University

Country
arrow
VMX
Not Confirmed

Lead Product(s) : Inclisiran Sodium,Inclisiran

Therapeutic Area : Undisclosed

Highest Development Status : Phase IV

Partner/Sponsor/Collaborator : Novartis Pharmaceuticals Corporation | Colorado Prevention Center | Mount Sinai Hospital, New York

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Inclisiran Sodium is a Oligonucleotide drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of undefined medical condition.

Product Name : Undisclosed

Product Type : Oligonucleotide

Upfront Cash : Inapplicable

April 03, 2025

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  • Development Update

Details:

Inclisiran Sodium is a Oligonucleotide drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Metabolic Syndrome.


Lead Product(s): Inclisiran Sodium,Inclisiran

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed

Study Phase: Phase IVProduct Type: Oligonucleotide

Sponsor: Novartis Pharmaceuticals Corporation

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable March 10, 2025

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04

University of California, San Diego

Country
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VMX
Not Confirmed

University of California, San Diego

Country
arrow
VMX
Not Confirmed

Details : Inclisiran Sodium is a Oligonucleotide drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Metabolic Syndrome.

Product Name : Undisclosed

Product Type : Oligonucleotide

Upfront Cash : Inapplicable

March 10, 2025

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Details:

Pelacarsen is a Oligonucleotide drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Atherosclerosis.


Lead Product(s): Pelacarsen,Inclisiran

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Oligonucleotide

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 07, 2025

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05

VMX
Not Confirmed
VMX
Not Confirmed

Details : Pelacarsen is a Oligonucleotide drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Atherosclerosis.

Product Name : Undisclosed

Product Type : Oligonucleotide

Upfront Cash : Inapplicable

February 07, 2025

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Details:

Inclisiran is a Oligonucleotide drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Homozygous Familial Hypercholesterolemia.


Lead Product(s): Inclisiran,Inapplicable

Therapeutic Area: Genetic Disease Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Oligonucleotide

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable September 19, 2024

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06

VMX
Not Confirmed
VMX
Not Confirmed

Details : Inclisiran is a Oligonucleotide drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Homozygous Familial Hypercholesterolemia.

Product Name : Undisclosed

Product Type : Oligonucleotide

Upfront Cash : Inapplicable

September 19, 2024

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Details:

Inclisiran is a Oligonucleotide drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Heterozygous Familial Hypercholesterolemia.


Lead Product(s): Inclisiran,Inapplicable

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Oligonucleotide

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable September 19, 2024

blank

07

VMX
Not Confirmed
VMX
Not Confirmed

Details : Inclisiran is a Oligonucleotide drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Heterozygous Familial Hypercholesterolemia.

Product Name : Undisclosed

Product Type : Oligonucleotide

Upfront Cash : Inapplicable

September 19, 2024

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Details:

Leqvio (inclisiran), the first and only approved siRNA indicated in patients with low or moderate risk of developing atherosclerotic cardiovascular disease and not receiving lipid-lowering therapy.


Lead Product(s): Inclisiran,Inapplicable

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Leqvio

Study Phase: Approved FDFProduct Type: Oligonucleotide

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable August 28, 2024

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08

VMX
Not Confirmed
VMX
Not Confirmed

Details : Leqvio (inclisiran), the first and only approved siRNA indicated in patients with low or moderate risk of developing atherosclerotic cardiovascular disease and not receiving lipid-lowering therapy.

Product Name : Leqvio

Product Type : Oligonucleotide

Upfront Cash : Inapplicable

August 28, 2024

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Details:

Leqvio (inclisiran), approved in over 80 countries, is the first and only approved Small interfering RNA therapy with a successful synthesis of the antisense strand of this drug.


Lead Product(s): Inclisiran,Inapplicable

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Leqvio

Study Phase: Approved FDFProduct Type: Oligonucleotide

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable July 09, 2024

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09

VMX
Not Confirmed
VMX
Not Confirmed

Details : Leqvio (inclisiran), approved in over 80 countries, is the first and only approved Small interfering RNA therapy with a successful synthesis of the antisense strand of this drug.

Product Name : Leqvio

Product Type : Oligonucleotide

Upfront Cash : Inapplicable

July 09, 2024

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Details:

Inclisiran is a Oligonucleotide drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Hypercholesterolemia.


Lead Product(s): Inclisiran,Inapplicable

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed

Study Phase: Phase IVProduct Type: Oligonucleotide

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable April 26, 2024

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10

VMX
Not Confirmed
VMX
Not Confirmed

Details : Inclisiran is a Oligonucleotide drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Hypercholesterolemia.

Product Name : Undisclosed

Product Type : Oligonucleotide

Upfront Cash : Inapplicable

April 26, 2024

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Patents & EXCLUSIVITIES

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US Patents

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01

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Not Confirmed

NOVARTIS

Switzerland
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VMX
Not Confirmed

INCLISIRAN SODIUM

US Patent Number : 12460206

Drug Substance Claim : Y

Drug Product Claim : Y

Application Number : 214012

Patent Use Code :

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2034-08-18

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02

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VMX
Not Confirmed

NOVARTIS

Switzerland
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VMX
Not Confirmed

INCLISIRAN SODIUM

US Patent Number : 10131907

Drug Substance Claim : Y

Drug Product Claim : Y

Application Number : 214012

Patent Use Code : U-4249

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2028-08-24

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03

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VMX
Not Confirmed

NOVARTIS

Switzerland
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VMX
Not Confirmed

INCLISIRAN SODIUM

US Patent Number : 9370582

Drug Substance Claim : Y

Drug Product Claim : Y

Application Number : 214012

Patent Use Code : U-4249

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2028-12-04

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04

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VMX
Not Confirmed

NOVARTIS

Switzerland
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VMX
Not Confirmed

INCLISIRAN SODIUM

US Patent Number : 8828956

Drug Substance Claim : Y

Drug Product Claim : Y

Application Number : 214012

Patent Use Code : U-4249

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2028-12-04

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05

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VMX
Not Confirmed

NOVARTIS

Switzerland
arrow
VMX
Not Confirmed

INCLISIRAN SODIUM

US Patent Number : 8809292

Drug Substance Claim : Y

Drug Product Claim : Y

Application Number : 214012

Patent Use Code : U-4249

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2027-05-10

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06

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VMX
Not Confirmed

NOVARTIS

Switzerland
arrow
VMX
Not Confirmed

INCLISIRAN SODIUM

US Patent Number : 8222222

Drug Substance Claim :

Drug Product Claim :

Application Number : 214012

Patent Use Code : U-4249

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2027-12-29

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07

arrow
VMX
Not Confirmed

NOVARTIS

Switzerland
arrow
VMX
Not Confirmed

INCLISIRAN SODIUM

US Patent Number : 8106022

Drug Substance Claim : Y

Drug Product Claim : Y

Application Number : 214012

Patent Use Code : U-4249

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2029-12-12

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08

arrow
VMX
Not Confirmed

NOVARTIS

Switzerland
arrow
VMX
Not Confirmed

INCLISIRAN SODIUM

US Patent Number : 10125369

Drug Substance Claim : Y

Drug Product Claim : Y

Application Number : 214012

Patent Use Code : U-4249

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2034-08-18

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09

arrow
VMX
Not Confirmed

NOVARTIS

Switzerland
arrow
VMX
Not Confirmed

INCLISIRAN SODIUM

US Patent Number : 10806791

Drug Substance Claim : Y

Drug Product Claim :

Application Number : 214012

Patent Use Code :

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2028-12-04

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10

arrow
VMX
Not Confirmed

NOVARTIS

Switzerland
arrow
VMX
Not Confirmed

INCLISIRAN SODIUM

US Patent Number : 10851377

Drug Substance Claim :

Drug Product Claim :

Application Number : 214012

Patent Use Code : U-4249

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2036-08-25

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