Find Diamorphine Hydrochloride manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Diamorphine hydrochloride, Diacetylmorphine hydrochloride, 1502-95-0, Diacetylmorphine hcl, Heroine hydrochloride, (-)-heroin hydrochloride
Molecular Formula
C21H24ClNO5
Molecular Weight
405.9  g/mol
InChI Key
FZJYQGFGNHGSFX-PVQKIFDLSA-N
FDA UNII
8H672SHT8E

Diamorphine Hydrochloride
A narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed)
1 2D Structure

Diamorphine Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl] acetate;hydrochloride
2.1.2 InChI
InChI=1S/C21H23NO5.ClH/c1-11(23)25-16-6-4-13-10-15-14-5-7-17(26-12(2)24)20-21(14,8-9-22(15)3)18(13)19(16)27-20;/h4-7,14-15,17,20H,8-10H2,1-3H3;1H/t14-,15+,17-,20-,21-;/m0./s1
2.1.3 InChI Key
FZJYQGFGNHGSFX-PVQKIFDLSA-N
2.1.4 Canonical SMILES
CC(=O)OC1C=CC2C3CC4=C5C2(C1OC5=C(C=C4)OC(=O)C)CCN3C.Cl
2.1.5 Isomeric SMILES
CC(=O)O[C@H]1C=C[C@H]2[C@H]3CC4=C5[C@]2([C@H]1OC5=C(C=C4)OC(=O)C)CCN3C.Cl
2.2 Other Identifiers
2.2.1 UNII
8H672SHT8E
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Diacetylmorphine

2. Diacetylmorphine Hydrochloride

3. Diagesil

4. Diamorf

5. Diamorphine

6. Heroin

7. Hydrochloride, Diacetylmorphine

8. Hydrochloride, Heroin

9. Min I Jet Morphine Sulphate

10. Min-i-jet Morphine Sulphate

2.3.2 Depositor-Supplied Synonyms

1. Diamorphine Hydrochloride

2. Diacetylmorphine Hydrochloride

3. 1502-95-0

4. Diacetylmorphine Hcl

5. Heroine Hydrochloride

6. (-)-heroin Hydrochloride

7. Heroin Hydrochloride Solution

8. O,o'-diacetylmorphine Hydrochloride

9. Nsc-302357

10. 8h672sht8e

11. Diacetylmorphine Hydrochloride Ci

12. Morphine, Diacetate (ester), Hydrochloride

13. Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, Diacetate

14. Morphinan-3,6alpha-diol, 7,8-didehydro-4,5alpha-epoxy-17-methyl-,

15. Morphinan-3,6-alpha-diol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-, Diacetate (ester), Hydrochloride

16. Einecs 216-124-5

17. Nsc 302357

18. Unii-8h672sht8e

19. Diamorphine (tn)

20. Heroin, Hydrochloride

21. Diamorphine, Hydrochloride

22. Ncgc00247702-01

23. Dsstox_cid_28835

24. Dsstox_rid_83104

25. Dsstox_gsid_48909

26. Schembl116481

27. Chembl2106627

28. Dtxsid2048909

29. Diamorphine Hydrochloride Anhydrous

30. Baa50295

31. Tox21_112854

32. Diacetylmorphine Hydrochloride [usp]

33. Nsc302357

34. Diamorphine Hydrochloride [mart.]

35. Diamorphine Hydrochloride [who-dd]

36. Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5alpha,6alpha)-, Diacetate (ester), Hydrochloride

37. Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5alpha,6alpha)-,diacetate (ester), Hydrochloride

38. Morphinan-3,6alpha-diol, 7,8-didehydro-4,5alpha-epoxy-17-methyl-, Diacetate (ester), Hydrochloride

39. Cas-1502-95-0

40. D07810

41. Diacetylmorphine Hydrochloride Ci [usp-rs]

42. Q27270475

43. Morphinan-3, 7,8-didehydro-4,5.alpha.-epoxy-17-methyl-, Diacetate (ester) Hydrochloride

44. Morphinan-3, 7,8-didehydro-4,5.alpha.-epoxy-17-methyl-, Diacetate (ester), Hydrochloride

45. Wln: T B6566 B6/co 4abbc R Bx Ho Pn Du Ght&&ttj Fov1 Jov1 P1 &gh

46. (5.alpha.,6.alpha.)-7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol Diacetate (ester) Hydrochloride

47. [(4r,4ar,7s,7ar,12bs)-9-acetyloxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1h-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl] Acetate;hydrochloride

48. Heroin Hydrochloride Solution, 100 Mug/ml In Methanol, Analytical Standard, For Drug Analysis

49. Morphinan-3, 7,8-didehydro-4,5-epoxy-17-methyl- (5.alpha.,6.alpha.)-, Diacetate (ester), Hydrochloride

50. Morphinan-3, 7,8-didehydro-4,5-epoxy-17-methyl- (5.alpha.,6.alpha.)-,diacetate (ester), Hydrochloride

51. Morphinan-3, 7,8-didehydro-4,5-epoxy-17-methyl-, Diacetate (ester), Hydrochloride, (5.alpha.,6.alpha.)-

2.3.3 Other Synonyms

1. Heroin

2. Acetomorphine

3. Diamorphine

4. Acetomorfine

5. Diacetylmorfin

6. Aspron

7. Heroien

8. Morphacetin

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 405.9 g/mol
Molecular Formula C21H24ClNO5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass405.1343006 g/mol
Monoisotopic Mass405.1343006 g/mol
Topological Polar Surface Area65.1 Ų
Heavy Atom Count28
Formal Charge0
Complexity692
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Indication

Dependence to intravenous heroin use


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Analgesics, Opioid

Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)


Narcotics

Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS. (See all compounds classified as Narcotics.)


Listed Suppliers

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Veranova

U.S.A
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  • EDQM
  • WHO-GMP

Virtual BoothVeranova: A CDMO that manages complexity with confidence.

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Diamorphine Hydrochloride

About the Company : Veranova is a global leader in the development and manufacturing of specialist and complex APIs for pharma and biotech customers. We have over 50 years of experience navigating the...

Veranova is a global leader in the development and manufacturing of specialist and complex APIs for pharma and biotech customers. We have over 50 years of experience navigating the challenges of the global healthcare industry, and nurturing long-standing, trusted customer relationships. Operating within two divisions, Generics and Originators, we deliver a differentiated service offering to pharma and biotech customers for every stage in the drug development lifecycle. Macfarlan Smith Limited is trading as Veranova in the United Kingdom.
Veranova

02

Alcaliber

Spain
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Alcaliber

Spain
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Diamorphine Hydrochloride

About the Company : Alcaliber is a benchmark in the World Drug Industry both in terms of quality and innovation, integrity and commitment to our customers. We are a leading company: in 2014 we were th...

Alcaliber is a benchmark in the World Drug Industry both in terms of quality and innovation, integrity and commitment to our customers. We are a leading company: in 2014 we were the largest world producer of Morphine, accounting for 27% of global production, as well as 18% of Thebaine (INCB 2015 – International Narcotics Control Board – Production Data 2014).
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Cambridge Bioscience

United Kingdom
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Cambridge Bioscience

United Kingdom
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Diamorphine Hydrochloride

About the Company : Cambridge Bioscience, a member of the Nordic BioSite Group, is a UK-based distributor of life science research and diagnostic products. With over 30 years’ experience working wit...

Cambridge Bioscience, a member of the Nordic BioSite Group, is a UK-based distributor of life science research and diagnostic products. With over 30 years’ experience working with life science researchers, we know that you have important decisions to make when choosing products and services for your research. We are here to support you and help you make those decisions, so you can focus on your next discovery.
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NEWS #PharmaBuzz

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US unveils proposal to ease restrictions on marijuana
US unveils proposal to ease restrictions on marijuana

16 May 2024

// Sarah N. Lynch REUTERS

https://www.reuters.com/business/healthcare-pharmaceuticals/us-unveils-proposal-ease-restrictions-marijuana-2024-05-16/

Sarah N. Lynch REUTERS
16 May 2024

http://www.pmlive.com/pharma_news/the_nhs_is_facing_shortages_of_lifesaving_treatments,_says_internal_document_1317319

Lucy Parsons PM LIVE
18 Nov 2019
FDA Consults on Abuse-Deterrent CNS Stimulants
FDA Consults on Abuse-Deterrent CNS Stimulants

20 Sep 2019

// Michael Mezher RAPS

https://www.raps.org/news-and-articles/news-articles/2019/9/fda-consults-on-abuse-deterrent-cns-stimulants

Michael Mezher RAPS
20 Sep 2019

https://www.reuters.com/article/us-usa-congress-fentanyl/top-lawmaker-signals-support-to-classify-all-illicit-fentanyl-copycats-like-heroin-idUSKCN1T5159

Sarah N. Lynch REUTERS
05 Jun 2019

https://www.prnewswire.com/news-releases/opioid-overdose-crisis-is-from-illicit-fentanyl-according-to-the-journal-of-american-physicians-and-surgeons-300618255.html

PR NEWSWIRE
22 Mar 2018

https://www.cnbc.com/2018/03/21/alex-azar-opioid-addiction-isnt-moral-issue-but-a-medical-condition.html?__source=twitter%7Cmain

B. Lovelace CNBC
21 Mar 2018

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XYZ Pharma

Gabon
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XYZ Pharma

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Diacetylmorphine Hydrochloride CI (25 mg) (AS...

CAS Number : 1502-95-0

Quantity Per Vial : 25

Sale Unit : mg

Price : $325.00

Details : Material Origin- Plant; USMCA- No; KORUS- No;...

Monograph :

Storage :

Code/Batch No : Catalog #1183002 / J1G200

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Looking for 1502-95-0 / Diamorphine Hydrochloride API manufacturers, exporters & distributors?

Diamorphine Hydrochloride manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Diamorphine Hydrochloride API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Diamorphine Hydrochloride manufacturer or Diamorphine Hydrochloride supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Diamorphine Hydrochloride manufacturer or Diamorphine Hydrochloride supplier.

PharmaCompass also assists you with knowing the Diamorphine Hydrochloride API Price utilized in the formulation of products. Diamorphine Hydrochloride API Price is not always fixed or binding as the Diamorphine Hydrochloride Price is obtained through a variety of data sources. The Diamorphine Hydrochloride Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Diamorphine Hydrochloride

Synonyms

Diacetylmorphine hydrochloride, 1502-95-0, Diacetylmorphine hcl, Heroine hydrochloride, (-)-heroin hydrochloride, Heroin hydrochloride solution

Cas Number

1502-95-0

Unique Ingredient Identifier (UNII)

8H672SHT8E

About Diamorphine Hydrochloride

A narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed)

Heroin Hydrochloride Manufacturers

A Heroin Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Heroin Hydrochloride, including repackagers and relabelers. The FDA regulates Heroin Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Heroin Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Heroin Hydrochloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Heroin Hydrochloride Suppliers

A Heroin Hydrochloride supplier is an individual or a company that provides Heroin Hydrochloride active pharmaceutical ingredient (API) or Heroin Hydrochloride finished formulations upon request. The Heroin Hydrochloride suppliers may include Heroin Hydrochloride API manufacturers, exporters, distributors and traders.

click here to find a list of Heroin Hydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Heroin Hydrochloride USDMF

A Heroin Hydrochloride DMF (Drug Master File) is a document detailing the whole manufacturing process of Heroin Hydrochloride active pharmaceutical ingredient (API) in detail. Different forms of Heroin Hydrochloride DMFs exist exist since differing nations have different regulations, such as Heroin Hydrochloride USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Heroin Hydrochloride DMF submitted to regulatory agencies in the US is known as a USDMF. Heroin Hydrochloride USDMF includes data on Heroin Hydrochloride's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Heroin Hydrochloride USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Heroin Hydrochloride suppliers with USDMF on PharmaCompass.

Heroin Hydrochloride GMP

Heroin Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Heroin Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Heroin Hydrochloride GMP manufacturer or Heroin Hydrochloride GMP API supplier for your needs.

Heroin Hydrochloride CoA

A Heroin Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Heroin Hydrochloride's compliance with Heroin Hydrochloride specifications and serves as a tool for batch-level quality control.

Heroin Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Heroin Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Heroin Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Heroin Hydrochloride EP), Heroin Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Heroin Hydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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