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Chemistry

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Also known as: (2s,3s,4r,5r,6r)-6-{[(2s,3s,4s,5r,6s)-6-{[(2r,3s,4s,5r)-2-carboxy-4,6-dihydroxy-5-(sulfooxy)oxan-3-yl]oxy}-2-hydroxy-4-(sulfomethyl)-5-(sulfooxy)oxan-3-yl]oxy}-3-{[(2r,3r,4r,5s,6r)-3-acetamido-4,5-dihydroxy-6-[(sulfooxy)methyl]oxan-2-yl]oxy}-4,5-dihydroxyoxane-2-carboxylic acid, Hepflush, Chembl526514, Gtpl4214, S01xa14, Bdbm50480251
Molecular Formula
C26H41NO34S4
Molecular Weight
1039.9  g/mol
InChI Key
ZFGMDIBRIDKWMY-PASTXAENSA-N

Heparin Sodium
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.
1 2D Structure

Heparin Sodium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,3S,4R,5R,6R)-3-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(sulfooxymethyl)oxan-2-yl]oxy-6-[(2S,3S,4S,5R,6S)-6-[(2R,3S,4S,5R)-2-carboxy-4,6-dihydroxy-5-sulfooxyoxan-3-yl]oxy-2-hydroxy-4-(sulfomethyl)-5-sulfooxyoxan-3-yl]oxy-4,5-dihydroxyoxane-2-carboxylic acid
2.1.2 InChI
InChI=1S/C26H41NO34S4/c1-4(28)27-7-9(30)8(29)6(2-52-63(43,44)45)53-24(7)56-15-10(31)11(32)25(58-19(15)21(36)37)55-13-5(3-62(40,41)42)14(60-64(46,47)48)26(59-22(13)38)57-16-12(33)17(61-65(49,50)51)23(39)54-18(16)20(34)35/h5-19,22-26,29-33,38-39H,2-3H2,1H3,(H,27,28)(H,34,35)(H,36,37)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)/t5-,6+,7+,8+,9+,10+,11+,12-,13-,14+,15-,16-,17+,18+,19-,22-,23?,24+,25+,26-/m0/s1
2.1.3 InChI Key
ZFGMDIBRIDKWMY-PASTXAENSA-N
2.1.4 Canonical SMILES
CC(=O)NC1C(C(C(OC1OC2C(C(C(OC2C(=O)O)OC3C(C(C(OC3O)OC4C(C(C(OC4C(=O)O)O)OS(=O)(=O)O)O)OS(=O)(=O)O)CS(=O)(=O)O)O)O)COS(=O)(=O)O)O)O
2.1.5 Isomeric SMILES
CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O[C@H]2[C@@H]([C@H]([C@@H](O[C@@H]2C(=O)O)O[C@H]3[C@@H]([C@H]([C@H](O[C@@H]3O)O[C@H]4[C@@H]([C@H](C(O[C@H]4C(=O)O)O)OS(=O)(=O)O)O)OS(=O)(=O)O)CS(=O)(=O)O)O)O)COS(=O)(=O)O)O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Alpha Heparin

2. Alpha-heparin

3. Heparin

4. Heparin Sodium

5. Heparin, Sodium

6. Heparin, Unfractionated

7. Heparinic Acid

8. Liquaemin

9. Unfractionated Heparin

2.2.2 Depositor-Supplied Synonyms

1. (2s,3s,4r,5r,6r)-6-{[(2s,3s,4s,5r,6s)-6-{[(2r,3s,4s,5r)-2-carboxy-4,6-dihydroxy-5-(sulfooxy)oxan-3-yl]oxy}-2-hydroxy-4-(sulfomethyl)-5-(sulfooxy)oxan-3-yl]oxy}-3-{[(2r,3r,4r,5s,6r)-3-acetamido-4,5-dihydroxy-6-[(sulfooxy)methyl]oxan-2-yl]oxy}-4,5-dihydroxyoxane-2-carboxylic Acid

2. Hepflush

3. Chembl526514

4. Gtpl4214

5. S01xa14

6. Bdbm50480251

7. (2s,3s,4r,5r,6r)-3-[(2r,3r,4r,5s,6r)-3-acetamido-4,5-dihydroxy-6-(sulfooxymethyl)oxan-2-yl]oxy-6-[(2s,3s,4s,5r,6s)-6-[(2r,3s,4s,5r)-2-carboxy-4,6-dihydroxy-5-sulfooxyoxan-3-yl]oxy-2-hydroxy-4-(sulfomethyl)-5-sulfooxyoxan-3-yl]oxy-4,5-dihydroxyoxane-2-carboxylic Acid

2.2.3 Other Synonyms

1. 9005-49-6

2.3 Create Date
2007-12-05
3 Chemical and Physical Properties
Molecular Weight 1039.9 g/mol
Molecular Formula C26H41NO34S4
XLogP3-10.4
Hydrogen Bond Donor Count14
Hydrogen Bond Acceptor Count34
Rotatable Bond Count18
Exact Mass1039.0392821 g/mol
Monoisotopic Mass1039.0392821 g/mol
Topological Polar Surface Area589 Ų
Heavy Atom Count65
Formal Charge0
Complexity2140
Isotope Atom Count0
Defined Atom Stereocenter Count19
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameHeparin sodium
Drug LabelIntravenous solutions with heparin sodium (derived from porcine intestinal mucosa) are sterile, nonpyrogenic fluids for intravenous administration. They contain no bacteriostat or antimicrobial agent or added buffer. Edetate disodium, anhydrous is ad...
Active IngredientHeparin sodium
Dosage FormInjectable
RouteInjection
Strength5,000 units/ml; 10,000 units/ml; 20,000 units/ml; 1,000 units/ml
Market StatusPrescription
CompanyHospira; Shenzhen Techdow; Sandoz; Pfizer; Fresenius Kabi Usa; Hikma Maple; Sagent Pharms

2 of 2  
Drug NameHeparin sodium
Drug LabelIntravenous solutions with heparin sodium (derived from porcine intestinal mucosa) are sterile, nonpyrogenic fluids for intravenous administration. They contain no bacteriostat or antimicrobial agent or added buffer. Edetate disodium, anhydrous is ad...
Active IngredientHeparin sodium
Dosage FormInjectable
RouteInjection
Strength5,000 units/ml; 10,000 units/ml; 20,000 units/ml; 1,000 units/ml
Market StatusPrescription
CompanyHospira; Shenzhen Techdow; Sandoz; Pfizer; Fresenius Kabi Usa; Hikma Maple; Sagent Pharms

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Anticoagulants

Agents that prevent BLOOD CLOTTING. (See all compounds classified as Anticoagulants.)


Fibrinolytic Agents

Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN. (See all compounds classified as Fibrinolytic Agents.)


USDMF

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DMF Review : Complete

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DMF Number : 7944

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Pfizer Inc

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Virtual BoothSmithfield BioScience transforms bioproducts into trusted, life-saving therapies through safe, reliable U.S.-based manufacturing.

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Heparin Sodium

About the Company : Smithfield BioScience specializes in harvesting and repurposing porcine-derived biological materials for use in pharmaceuticals, medical devices, regenerative medicine, and nutrace...

Smithfield BioScience specializes in harvesting and repurposing porcine-derived biological materials for use in pharmaceuticals, medical devices, regenerative medicine, and nutraceuticals. Operating one of the only fully US-based supply chains for Heparin Sodium USP/EP, the company ensures the highest standards of safety and quality at its USDA-approved, FDA-registered facility in Cincinnati, Ohio. With a mission to advance human health, Smithfield BioScience invests in research and development, exploring new uses for bioproducts-from gelatin agents to tissue fabrication-delivering breakthrough solutions worldwide.
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Bioiberica

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About the Company : Bioiberica is a global Life Science company with more than 45 years' experience in the production and development of molecules of high biological and therapeutic value for the phar...

Bioiberica is a global Life Science company with more than 45 years' experience in the production and development of molecules of high biological and therapeutic value for the pharmaceutical and nutraceutical industries. This specialisation positions Bioiberica among the leading Heparin API manufacturers and as a world reference of other biologically-derived APIs and scientifically backed nutraceutical ingredients for mobility, digestive health and skin & beauty. Through its vertically integrated supply chain, Bioiberica ensures the highest quality, safety and full traceability of its products, which are produced in Europe.
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About the Company : Established in 1982, ChemWerth is a US-headquartered full-service generic active pharmaceutical ingredient (API) development and supply company. ChemWerth offers cGMP-quality APIs ...

Established in 1982, ChemWerth is a US-headquartered full-service generic active pharmaceutical ingredient (API) development and supply company. ChemWerth offers cGMP-quality APIs to regulated markets worldwide and has exclusive partnerships for new product development, compliance support and secure supply chain logistics. ChemWerth has access to over 500 APIs and more than 30 manufacturing facilities in the US, Europe, India and China. ChemWerth acts as a regulatory agent for over 25 FDA-approved facilities and sells more than 100 products. It has established its presence in 38 countries. In 2020, ChemWerth filed its 500th DMF with the FDA.
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About the Company : LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, ...

LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, analytical method development and testing, and commercial manufacturing. LGM Pharma offers custom API synthesis, analytical development, and regulatory services. With a network of over 300 accredited CGMP manufacturing partners, LGM provides unparalleled supply chain security. And, with over 100,000 square feet of FDA-inspected cGMP manufacturing and warehouse capacity, LGM Pharma provides a one-stop solution for solid dose, powder, semi-solid and liquid drugs.
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About the Company : Faran Shimi Pharmaceutical Company, established in 2001 and affiliated with Golrang Pharmaceutical Investment Co, manufactures high-quality Active Pharmaceutical Ingredients (APIs)...

Faran Shimi Pharmaceutical Company, established in 2001 and affiliated with Golrang Pharmaceutical Investment Co, manufactures high-quality Active Pharmaceutical Ingredients (APIs) and finished dosage forms. For the past three years, the company focused on extracting alkaloid opiates, controlled substances, and narcotics. The APIs are widely used by major pharmaceutical companies nationwide and exported to the Middle East. All production adheres to local GMP standards in an SOP-driven environment with modern systems and utilities, ensuring the highest quality and safety.
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About the Company : Pfizer CentreOne® is an altogether different global contract development and manufacturing organization (CDMO), and a leading supplier of specialty APIs and intermediates.
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Pfizer CentreOne® is an altogether different global contract development and manufacturing organization (CDMO), and a leading supplier of specialty APIs and intermediates. Backed by Pfizer resources, we’ve been delivering technical expertise, regulatory support and long-term supply for over 40 years. With 35+ sites across six continents, our expansive network allows us to securely and efficiently guide complex compounds from development through commercial manufacture. For more information, visit http://www.pfizercentreone.com
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About the Company : Shamrock Pharmachemi Pvt Ltd. is a globally recognized API leader with over 26 years of expertise in human and veterinary pharmaceuticals. Operating in 40+ countries, we own two st...

Shamrock Pharmachemi Pvt Ltd. is a globally recognized API leader with over 26 years of expertise in human and veterinary pharmaceuticals. Operating in 40+ countries, we own two state-of-the-art manufacturing facilities in Gujarat and collaborate with 16+ exclusive partner plants. Proudly holding the title of 'Largest Exporter for 12 Molecules Worldwide', we maintain the highest quality standards including USFDA, EU-GMP, WHO-GMP, and other stringent international certifications. Our robust regulatory compliance (DMF, CEP, ICH Q7) and customer-focused approach make us the preferred 'API Partner in India' for pharmaceutical companies worldwide
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HELM Portugal

Portugal
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HELM Portugal

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Heparin

About the Company : HELM Portugal is HELM’s Competence Centre for the marketing of Active Pharmaceutical Ingredients (API). The leading APIs distributed by Helm include Ascorbic Acid pharma Grade (C...

HELM Portugal is HELM’s Competence Centre for the marketing of Active Pharmaceutical Ingredients (API). The leading APIs distributed by Helm include Ascorbic Acid pharma Grade (CEP), Heparin Sodium (CEP holder), Dimetindene Maleate EP. Helm supply high-quality pharmaceuticals and provide a broad range of services on a global scale. Our services include: Logistics and distribution, Sourcing on Demand, Regulatory Affairs and Quality.
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About the Company : QINGDAO QINGMEI BIOTECH(hereinafter referred to as Qingmei) is a specialized pharmaceutical company founded by DAYON INTERNATIONAL HOLDING LIMITED, which is to expand international...

QINGDAO QINGMEI BIOTECH(hereinafter referred to as Qingmei) is a specialized pharmaceutical company founded by DAYON INTERNATIONAL HOLDING LIMITED, which is to expand international business and strategic cooperation with suppliers. The company is located in the beautiful coastal city of Qingdao, near City Hall and the May Fourth Square, and also close to the port, so that it has convenient traffic conditions for trade. The company's business focuses on the development and promotion of the pharmaceutical chemicals, animal health, food additives, plant extracts, cosmetic raw materials, intermediates and other fine chemicals.
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Heparin Sodium

About the Company : The company is a professional manufacturer of active biological extracts. We adhere to the market-oriented business philosophy. The international and domestic markets take advantag...

The company is a professional manufacturer of active biological extracts. We adhere to the market-oriented business philosophy. The international and domestic markets take advantage of China's abundant raw material resources to develop animal organ extracts. The company mainly produces trypsin and trypsin. , chymotrypsin, trypsin enzymes , pancreatic kallikrein, pepsin, elastase, sodium, cytochrome C, hemoglobin, bovine liver extract, chondroitin sulfate, and other products, marketing the United States, Germany, Japan, Korea, etc. Countries and regions have established good long-term partnerships with customers around the world.
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PRODUCT","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"KILITCH DRUGS INDIA LTD","customerCountry":"INDIA","quantity":"0.40","actualQuantity":"0.396","unit":"KGS","unitRateFc":"4617.4","totalValueFC":"1842.9","currency":"USD","unitRateINR":"403100.3","date":"24-Mar-2025","totalValueINR":"159627.7","totalValueInUsd":"1842.9","indian_port":"Bombay Air","hs_no":"29379090","bill_no":"9070418","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"S IMPORT &EXPORT CO.LTD.6-7\/F,310 N ORTH ZHONGSHAN ROAD,HANGZHOU,310003 SDNF CHINA","customerAddress":"3RD,FL,UJAGAR INDUSTRIAL ESTATE,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1744828200,"product":"HEPARIN SODIUM (1500 MIU HEPARIN SODIUM IP","address":"PLOT NO 54 AND 55 INDUSTRIAL AREA,","city":"CHANDIGARH,CHANDIGARH","supplier":"YINO PHARMA LTD","supplierCountry":"CHINA","foreign_port":"CHONGQING","customer":"SCOTT EDIL PHARMACIA LTD","customerCountry":"INDIA","quantity":"7.11","actualQuantity":"7.11","unit":"KGS","unitRateFc":"4019.7","totalValueFC":"28913","currency":"USD","unitRateINR":"348101.9","date":"17-Apr-2025","totalValueINR":"2475004.2","totalValueInUsd":"28913","indian_port":"Delhi Air","hs_no":"29419090","bill_no":"9557497","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"CHONGQING","supplierAddress":"2 CUIPING ERXIANG YUBEI DISTRICT CHONGQING 401120 SDNF CHINA","customerAddress":"PLOT NO 54 AND 55 INDUSTRIAL AREA,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1745260200,"product":"ENOXAPARIN SODIUM [LOW MOLECULAR WEIGHT HEPARIN] ENOXAPARIN SODIUM IP [LOW MOLECULAR WEIGHT HEPARIN]","address":"T-184, MIDC, BHOSARI,","city":"PUNE-MAHARASHTRA","supplier":"SHENZHEN TECHDOW PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"EMCURE PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"7.04","actualQuantity":"7.04","unit":"KGS","unitRateFc":"7300","totalValueFC":"51871.2","currency":"USD","unitRateINR":"630720","date":"22-Apr-2025","totalValueINR":"4440268.8","totalValueInUsd":"51871.2","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"9645068","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"NO. 19, GAOXINZHONGYI ROAD, NANSHAN DISTRICT, SHENZHEN 518057 CHINA Sh enzhen, , China China","customerAddress":"T-184, MIDC, BHOSARI,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1745260200,"product":"ENOXAPARIN SODIUM [LOW MOLECULAR WEIGHT HEPARIN] ENOXAPARIN SODIUM [LOW MOLECULAR WEIGHT HEPARIN]","address":"T-184, MIDC, BHOSARI,","city":"PUNE-MAHARASHTRA","supplier":"SHENZHEN TECHDOW PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"EMCURE PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"2.02","actualQuantity":"2.02","unit":"KGS","unitRateFc":"7300","totalValueFC":"14883.5","currency":"USD","unitRateINR":"630720","date":"22-Apr-2025","totalValueINR":"1274054.4","totalValueInUsd":"14883.5","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"9645068","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"NO. 19, GAOXINZHONGYI ROAD, NANSHAN DISTRICT, SHENZHEN 518057 CHINA Sh enzhen, , China China","customerAddress":"T-184, MIDC, BHOSARI,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1747765800,"product":"HEPARIN SODIUM BP (4.386 KGS) HEPARIN SODIUM BP (4.386 KGS)","address":"12\/12, SHAKTI NAGAR,","city":"DELHI","supplier":"JIANGXI ERYE PHARMACEUTICAL MARKETING COLTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"COOPER PHARMA LTD","customerCountry":"INDIA","quantity":"4.39","actualQuantity":"4.386","unit":"KGS","unitRateFc":"4674","totalValueFC":"20788.6","currency":"USD","unitRateINR":"403830.4","date":"21-May-2025","totalValueINR":"1771200","totalValueInUsd":"20788.6","indian_port":"Delhi Air","hs_no":"29371900","bill_no":"2198633","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"ROOM 301, BUILDING 1, HEALTH INDUST RIAL PARK, NO.18 CENTURY AVENUE, XI NXING INDUSTRIAL PARK, YUSHUI DISTR CN","customerAddress":"12\/12, SHAKTI NAGAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1748543400,"product":"HEPARIN SODIUM ( 2000 MEGA) HEPARIN SODIUM ( 2000 MEGA)","address":"101, SITARAM MANSION,","city":"KAROL BAGH, NEW DELHI","supplier":"DONGYING TIANDONG PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"JODAS EXPOIM PRIVATE LTD","customerCountry":"INDIA","quantity":"10.12","actualQuantity":"10.121","unit":"KGS","unitRateFc":"3754.6","totalValueFC":"38534.9","currency":"USD","unitRateINR":"324394.8","date":"30-May-2025","totalValueINR":"3283200","totalValueInUsd":"38534.9","indian_port":"Hyderabad Air","hs_no":"29349990","bill_no":"2375482","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"NO 1236 NAN-ER ROAD DONGYING SHANDO NG SDNF China","customerAddress":"101, SITARAM MANSION,"}]
15-Jan-2022
30-May-2025
KGS
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Quantity (KGS) & Unit rate (USD/KGS) over time

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INTERMEDIATE SUPPLIERS

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01

Suanfarma

Spain
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSuanfarma, at the Core of a Better Life.

CAS Number : 9041-08-1

End Use API : Heparin Sodium

About The Company : Suanfarma founded in 1993, is a B2B life science partner committed to health advancement by developing, manufacturing, & distributing high-quality APIs for the ...

Suanfarma

02

Suanfarma

Spain
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSuanfarma, at the Core of a Better Life.

CAS Number : 9041-08-1

End Use API : Heparin Sodium

About The Company : Suanfarma founded in 1993, is a B2B life science partner committed to health advancement by developing, manufacturing, & distributing high-quality APIs for the ...

Suanfarma
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Europe

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01

Drossapharm AG

Switzerland
Pharmex
Not Confirmed
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Drossapharm AG

Switzerland
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Pharmex
Not Confirmed

Heparinum natricum; Symphyti radicis recentis extractum ethanolicum liquidum

Brand Name : Keppur

Dosage Form : Gel

Dosage Strength :

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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02

FARMIGEA SpA

Italy
Pharmex
Not Confirmed
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FARMIGEA SpA

Italy
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Pharmex
Not Confirmed

Heparin

Brand Name : Heparin

Dosage Form :

Dosage Strength : Coll 25,000 Iu 5 Ml  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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03

Pharmex
Not Confirmed
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Pharmex
Not Confirmed

Heparin

Brand Name : Epsoclar 25000

Dosage Form : Heparin Sodium 25,000Iu 1 Unit Parenteral Use

Dosage Strength : 1 bottle EV 25,000 IU/5 ml 5 ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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04

Pharmex
Not Confirmed
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Pharmex
Not Confirmed

Heparin

Brand Name : Epsoclar

Dosage Form : Heparin Sodium 25,000Iu 10 Units Parenteral Use

Dosage Strength : 10 VIALS EV 25,000 IU 5 ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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05

Pharmex
Not Confirmed
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Pharmex
Not Confirmed

Heparin

Brand Name : Epsodilave

Dosage Form : Heparin Sodium 250Iu 10 Units Parenteral Use

Dosage Strength : 10 vials 250 IU 5 ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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06

Pharmex
Not Confirmed
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Pharmex
Not Confirmed

Heparin

Brand Name : Calciparina

Dosage Form : Calcium Heparin 12.500Iu 10 Units Parenteral Use

Dosage Strength : 10 SYRINGES SC 12,500 IU 0.5 ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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07

Orifarm AB

Denmark
Pharmex
Not Confirmed
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Orifarm AB

Denmark
arrow
Pharmex
Not Confirmed

heparin sodium

Brand Name : Heparin LEO

Dosage Form : SOLUTION FOR INJECTION

Dosage Strength : 5000 IU / ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

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08

Orifarm AB

Denmark
Pharmex
Not Confirmed
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Orifarm AB

Denmark
arrow
Pharmex
Not Confirmed

heparin sodium

Brand Name : Heparin LEO

Dosage Form : SOLUTION FOR INJECTION

Dosage Strength : 5000 IU / ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

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09

2care4 ApS

Country
Pharmex
Not Confirmed
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2care4 ApS

Country
arrow
Pharmex
Not Confirmed

heparin sodium

Brand Name : Heparin LEO

Dosage Form : SOLUTION FOR INJECTION

Dosage Strength : 5000 IU / ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

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10

S.F.GROUP Srl

Country
Pharmex
Not Confirmed
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S.F.GROUP Srl

Country
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Pharmex
Not Confirmed

Heparin

Brand Name : Reoflus

Dosage Form : Calcium Heparin 12.500Iu 10 Units Parenteral Use

Dosage Strength : 10 fialesiringhe SC 12,500 IU 0.5 ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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Listed Dossiers

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01

Biological E

India
EPS
Not Confirmed
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Biological E

India
arrow
EPS
Not Confirmed

Heparin Sodium

Brand Name :

Dosage Form : Vial

Dosage Strength : 5000IU/ML

Packaging : 10 ml

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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01

Biological E

India
EPS
Not Confirmed
arrow

Biological E

India
arrow
EPS
Not Confirmed

Heparin Sodium

Dosage : Vial

Dosage Strength : 5000IU/ML

Brand Name :

Approval Date :

Application Number :

Registration Country : India

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02

Biological E

India
EPS
Not Confirmed
arrow

Biological E

India
arrow
EPS
Not Confirmed

Heparin Sodium

Brand Name :

Dosage Form : Vial

Dosage Strength : 5000IU/ML

Packaging : 1 ml

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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02

Biological E

India
EPS
Not Confirmed
arrow

Biological E

India
arrow
EPS
Not Confirmed

Heparin Sodium

Dosage : Vial

Dosage Strength : 5000IU/ML

Brand Name :

Approval Date :

Application Number :

Registration Country : India

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03

Biological E

India
EPS
Not Confirmed
arrow

Biological E

India
arrow
EPS
Not Confirmed

Heparin Sodium

Brand Name :

Dosage Form : Vial

Dosage Strength : 20000IU/ML

Packaging : 1 ml

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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03

Biological E

India
EPS
Not Confirmed
arrow

Biological E

India
arrow
EPS
Not Confirmed

Heparin Sodium

Dosage : Vial

Dosage Strength : 20000IU/ML

Brand Name :

Approval Date :

Application Number :

Registration Country : India

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04

EPS
Not Confirmed
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EPS
Not Confirmed

Heparin

Brand Name :

Dosage Form : Injection

Dosage Strength : 5000IU/5ML

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : India

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04

EPS
Not Confirmed
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EPS
Not Confirmed

Heparin

Dosage : Injection

Dosage Strength : 5000IU/5ML

Brand Name :

Approval Date :

Application Number :

Registration Country : India

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05

EPS
Not Confirmed
arrow
arrow
EPS
Not Confirmed

Heparin Sodium

Brand Name :

Dosage Form : Injection

Dosage Strength : 5000IU

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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05

EPS
Not Confirmed
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arrow
EPS
Not Confirmed

Heparin Sodium

Dosage : Injection

Dosage Strength : 5000IU

Brand Name :

Approval Date :

Application Number :

Registration Country : India

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06

EPS
Not Confirmed
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arrow
EPS
Not Confirmed

Heparin Sodium

Brand Name : Heparin

Dosage Form : Liquid Injection

Dosage Strength : 25000IU/ML

Packaging : 5 ML

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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06

EPS
Not Confirmed
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arrow
EPS
Not Confirmed

Heparin Sodium

Dosage : Liquid Injection

Dosage Strength : 25000IU/ML

Brand Name : Heparin

Approval Date :

Application Number :

Registration Country : India

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07

EPS
Not Confirmed
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EPS
Not Confirmed

Heparin Sodium

Brand Name : Heparinum

Dosage Form : Solution for IV Inject...

Dosage Strength : 25000IU/5ML

Packaging : 1 vial&10 vials

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Turkey

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07

EPS
Not Confirmed
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arrow
EPS
Not Confirmed

Heparin Sodium

Dosage : Solution for IV Inject...

Dosage Strength : 25000IU/5ML

Brand Name : Heparinum

Approval Date :

Application Number :

Registration Country : Turkey

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08

Pluviaendo

Turkey
EPS
Not Confirmed
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Pluviaendo

Turkey
arrow
EPS
Not Confirmed

Heparin Sodium

Brand Name :

Dosage Form : Ampoule

Dosage Strength : 2000IU/2ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Turkey

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08

Pluviaendo

Turkey
EPS
Not Confirmed
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Pluviaendo

Turkey
arrow
EPS
Not Confirmed

Heparin Sodium

Dosage : Ampoule

Dosage Strength : 2000IU/2ML

Brand Name :

Approval Date :

Application Number :

Registration Country : Turkey

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09

EPS
Not Confirmed
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EPS
Not Confirmed

Heparin Sodium

Brand Name :

Dosage Form : Injection

Dosage Strength : 5000IU/5ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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09

EPS
Not Confirmed
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EPS
Not Confirmed

Heparin Sodium

Dosage : Injection

Dosage Strength : 5000IU/5ML

Brand Name :

Approval Date :

Application Number :

Registration Country : India

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10

EPS
Not Confirmed
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EPS
Not Confirmed

Heparin Sodium

Brand Name :

Dosage Form : Injection

Dosage Strength : 5000IU/5ML

Packaging : 7.5 ml

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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10

EPS
Not Confirmed
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EPS
Not Confirmed

Heparin Sodium

Dosage : Injection

Dosage Strength : 5000IU/5ML

Brand Name :

Approval Date :

Application Number :

Registration Country : India

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - INJECTABLE;INJECTION - 1,000 UNITS/M...DOSAGE - INJECTABLE;INJECTION - 1,000 UNITS/ML

USFDA APPLICATION NUMBER - 17029

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DOSAGE - INJECTABLE;INJECTION - 10,000 UNITS/...DOSAGE - INJECTABLE;INJECTION - 10,000 UNITS/ML

USFDA APPLICATION NUMBER - 17029

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DOSAGE - INJECTABLE;INJECTION - 100 UNITS/ML

USFDA APPLICATION NUMBER - 17029

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DOSAGE - INJECTABLE;INJECTION - 20,000 UNITS/...DOSAGE - INJECTABLE;INJECTION - 20,000 UNITS/ML

USFDA APPLICATION NUMBER - 17029

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DOSAGE - INJECTABLE;INJECTION - 40 UNITS/ML

USFDA APPLICATION NUMBER - 17029

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DOSAGE - INJECTABLE;INJECTION - 5,000 UNITS/M...DOSAGE - INJECTABLE;INJECTION - 5,000 UNITS/ML

USFDA APPLICATION NUMBER - 17029

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DOSAGE - INJECTABLE;INJECTION - 50 UNITS/ML

USFDA APPLICATION NUMBER - 17029

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DOSAGE - INJECTABLE;INJECTION - 1,000 UNITS/M...DOSAGE - INJECTABLE;INJECTION - 1,000 UNITS/ML

USFDA APPLICATION NUMBER - 201370

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DOSAGE - INJECTABLE;INJECTION - 10,000 UNITS/...DOSAGE - INJECTABLE;INJECTION - 10,000 UNITS/ML

USFDA APPLICATION NUMBER - 201370

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DOSAGE - INJECTABLE;INJECTION - 5,000 UNITS/M...DOSAGE - INJECTABLE;INJECTION - 5,000 UNITS/ML

USFDA APPLICATION NUMBER - 201370

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ABOUT THIS PAGE

Looking for / Heparin Sodium API manufacturers, exporters & distributors?

Heparin Sodium manufacturers, exporters & distributors 1

29

PharmaCompass offers a list of Heparin Sodium API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Heparin Sodium manufacturer or Heparin Sodium supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Heparin Sodium manufacturer or Heparin Sodium supplier.

PharmaCompass also assists you with knowing the Heparin Sodium API Price utilized in the formulation of products. Heparin Sodium API Price is not always fixed or binding as the Heparin Sodium Price is obtained through a variety of data sources. The Heparin Sodium Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Heparin Sodium

Synonyms

(2s,3s,4r,5r,6r)-6-{[(2s,3s,4s,5r,6s)-6-{[(2r,3s,4s,5r)-2-carboxy-4,6-dihydroxy-5-(sulfooxy)oxan-3-yl]oxy}-2-hydroxy-4-(sulfomethyl)-5-(sulfooxy)oxan-3-yl]oxy}-3-{[(2r,3r,4r,5s,6r)-3-acetamido-4,5-dihydroxy-6-[(sulfooxy)methyl]oxan-2-yl]oxy}-4,5-dihydroxyoxane-2-carboxylic acid, Hepflush, Chembl526514, Gtpl4214, S01xa14, Bdbm50480251

About Heparin Sodium

A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.

Heparin Sodium Manufacturers

A Heparin Sodium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Heparin Sodium, including repackagers and relabelers. The FDA regulates Heparin Sodium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Heparin Sodium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Heparin Sodium manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Heparin Sodium Suppliers

A Heparin Sodium supplier is an individual or a company that provides Heparin Sodium active pharmaceutical ingredient (API) or Heparin Sodium finished formulations upon request. The Heparin Sodium suppliers may include Heparin Sodium API manufacturers, exporters, distributors and traders.

click here to find a list of Heparin Sodium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Heparin Sodium USDMF

A Heparin Sodium DMF (Drug Master File) is a document detailing the whole manufacturing process of Heparin Sodium active pharmaceutical ingredient (API) in detail. Different forms of Heparin Sodium DMFs exist exist since differing nations have different regulations, such as Heparin Sodium USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Heparin Sodium DMF submitted to regulatory agencies in the US is known as a USDMF. Heparin Sodium USDMF includes data on Heparin Sodium's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Heparin Sodium USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Heparin Sodium suppliers with USDMF on PharmaCompass.

Heparin Sodium JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Heparin Sodium Drug Master File in Japan (Heparin Sodium JDMF) empowers Heparin Sodium API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Heparin Sodium JDMF during the approval evaluation for pharmaceutical products. At the time of Heparin Sodium JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Heparin Sodium suppliers with JDMF on PharmaCompass.

Heparin Sodium KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Heparin Sodium Drug Master File in Korea (Heparin Sodium KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Heparin Sodium. The MFDS reviews the Heparin Sodium KDMF as part of the drug registration process and uses the information provided in the Heparin Sodium KDMF to evaluate the safety and efficacy of the drug.

After submitting a Heparin Sodium KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Heparin Sodium API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Heparin Sodium suppliers with KDMF on PharmaCompass.

Heparin Sodium CEP

A Heparin Sodium CEP of the European Pharmacopoeia monograph is often referred to as a Heparin Sodium Certificate of Suitability (COS). The purpose of a Heparin Sodium CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Heparin Sodium EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Heparin Sodium to their clients by showing that a Heparin Sodium CEP has been issued for it. The manufacturer submits a Heparin Sodium CEP (COS) as part of the market authorization procedure, and it takes on the role of a Heparin Sodium CEP holder for the record. Additionally, the data presented in the Heparin Sodium CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Heparin Sodium DMF.

A Heparin Sodium CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Heparin Sodium CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Heparin Sodium suppliers with CEP (COS) on PharmaCompass.

Heparin Sodium NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Heparin Sodium as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Heparin Sodium API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Heparin Sodium as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Heparin Sodium and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Heparin Sodium NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Heparin Sodium suppliers with NDC on PharmaCompass.

Heparin Sodium GMP

Heparin Sodium Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Heparin Sodium GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Heparin Sodium GMP manufacturer or Heparin Sodium GMP API supplier for your needs.

Heparin Sodium CoA

A Heparin Sodium CoA (Certificate of Analysis) is a formal document that attests to Heparin Sodium's compliance with Heparin Sodium specifications and serves as a tool for batch-level quality control.

Heparin Sodium CoA mostly includes findings from lab analyses of a specific batch. For each Heparin Sodium CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Heparin Sodium may be tested according to a variety of international standards, such as European Pharmacopoeia (Heparin Sodium EP), Heparin Sodium JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Heparin Sodium USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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