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    Chemistry

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    Also known as: 79559-97-0, Sertraline hcl, Zoloft, Gladem, Lustral, Serad
    Molecular Formula
    C17H18Cl3N
    Molecular Weight
    342.7  g/mol
    InChI Key
    BLFQGGGGFNSJKA-XHXSRVRCSA-N
    FDA UNII
    UTI8907Y6X
    Sertraline Hydrochloride
    A selective serotonin uptake inhibitor that is used in the treatment of depression.
    1 2D Structure

    Sertraline Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride
    2.1.2 InChI
    InChI=1S/C17H17Cl2N.ClH/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11;/h2-6,8,10,12,17,20H,7,9H2,1H3;1H/t12-,17-;/m0./s1
    2.1.3 InChI Key
    BLFQGGGGFNSJKA-XHXSRVRCSA-N
    2.1.4 Canonical SMILES
    CNC1CCC(C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl.Cl
    2.1.5 Isomeric SMILES
    CN[C@H]1CC[C@H](C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    UTI8907Y6X
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Altruline

    2. Apo Sertraline

    3. Apo-sertraline

    4. Aremis

    5. Besitran

    6. Gen Sertraline

    7. Gen-sertraline

    8. Gladem

    9. Hydrochloride, Sertraline

    10. Lustral

    11. Novo Sertraline

    12. Novo-sertraline

    13. Ratio Sertraline

    14. Ratio-sertraline

    15. Rhoxal Sertraline

    16. Rhoxal-sertraline

    17. Sealdin

    18. Sertraline

    19. Sertraline Hydrochloride (1s-cis)-isomer

    20. Zoloft

    2.3.2 Depositor-Supplied Synonyms

    1. 79559-97-0

    2. Sertraline Hcl

    3. Zoloft

    4. Gladem

    5. Lustral

    6. Serad

    7. (1s,4s)-4-(3,4-dichlorophenyl)-n-methyl-1,2,3,4-tetrahydronaphthalen-1-amine Hydrochloride

    8. Rac-cis-sertraline Hydrochloride

    9. Sertraline.hcl

    10. Sertraline (hydrochloride)

    11. 79617-95-1

    12. Nsc-746308

    13. Nsc-758948

    14. (+)-sertraline Hydrochloride

    15. Sertraline (as Hydrochloride)

    16. Sertraline Hydrechloride

    17. (1s,4s)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-naphthalenamine Hydrochloride

    18. Chebi:9124

    19. Uti8907y6x

    20. Cp-51974-1

    21. (+/-)-sertraline Hydrochloride

    22. Cp 51,974-1

    23. (1s,4s)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-naphthylamine Hydrochloride

    24. Atruline

    25. Tresleen

    26. Cp-51,974-1

    27. Tatig

    28. Dsstox_cid_20243

    29. Dsstox_rid_79456

    30. Dsstox_gsid_40243

    31. 1-naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-, Hydrochloride, (1s-cis)-

    32. Adjuvin

    33. Aremis

    34. Mls001401398

    35. Mfcd00895772

    36. (+)-cis-(1s,4s)-1-methylamino-4-(3,4-dichlorophenyl)tetralin Hydrochloride

    37. (1s,4s)-4-(3,4-dichlorophenyl)-n-methyl-1,2,3,4-tetrahydronaphthalen-1-aminium Chloride

    38. (1s-cis)-4-(3,4-dichlorophenyl)-n-methyl-1,2,3,4-tetrahydronaphthalen-1-amine Hydrochloride

    39. Cis-n-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenaminehydrochloride

    40. Cas-79559-97-0

    41. Sertraline Hydrochloride [usan]

    42. Ncgc00092386-03

    43. Smr000466298

    44. C17h17cl2n.hcl

    45. Unii-uti8907y6x

    46. Serlift

    47. Sertraline, Hcl

    48. Sertraline Hydrochloride [usan:usp]

    49. Zoloft (tn)

    50. (1s,4s)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-4-(methylamino)naphthalene Hydrochloride

    51. Cpd000466298

    52. (1s,4s)-4-(3,4-dichlorophenyl)-n-methyl-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride

    53. Sertraline Impurity G Hcl

    54. Chembl1709

    55. Schembl23230

    56. Mls000758929

    57. Spectrum1505262

    58. Sertraline Hydrochloride- Bio-x

    59. Dtxsid1040243

    60. Hy-b0176a

    61. Sertraline For System Suitability

    62. (1r,4s)-sertraline Hcl

    63. Sertraline For Peak Identification

    64. Cp-51974-1 Hcl

    65. Hms1922p09

    66. Pharmakon1600-01505262

    67. (1r,4s)-sertraline Hydrochloride

    68. (1rs,4sr)-4-(3,4-dichlorophenyl)-n-methyl-1,2,3,4-tetrahydronaphthalen-1-amine Hydrochloride

    69. Sertraline Hydrochloride (jan/usp)

    70. Tox21_111199

    71. Tox21_500870

    72. Ac-740

    73. Ccg-39575

    74. Nsc746308

    75. Nsc758948

    76. Sertraline Hydrochloride [mi]

    77. Sertraline Hydrochloride [jan]

    78. Akos005267232

    79. Akos015846322

    80. Tox21_111199_1

    81. Cs-2052

    82. Ks-1111

    83. Lp00870

    84. Nc00198

    85. Nc00726

    86. Nsc 746308

    87. Nsc 758948

    88. (1s-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-naphthalenamine Hydrochloride

    89. Sertraline Hydrochloride [mart.]

    90. Sertraline Hydrochloride [vandf]

    91. Ncgc00092386-01

    92. Ncgc00092386-13

    93. Ncgc00261555-01

    94. Sertraline Hydrochloride [usp-rs]

    95. Sertraline Hydrochloride [who-dd]

    96. Bs164399

    97. Sertraline Hydrochloride Impurity Standard

    98. Sertraline Hydrochloride Related Compound A

    99. Sertraline Hydrochloride, >=98% (hplc)

    100. Cp-5197401

    101. Eu-0100870

    102. S4053

    103. Sertraline Hydrochloride [ep Impurity]

    104. Sertraline Hydrochloride [orange Book]

    105. D00825

    106. O12070

    107. Sertraline Hydrochloride [ep Monograph]

    108. Sertraline Hydrochloride [usp Monograph]

    109. 559s970

    110. A839713

    111. Q27108281

    112. Sertraline Hydrochloride 100 Microg/ml In Acetonitrile

    113. Sertraline Hydrochloride 1.0 Mg/ml In Methanol (as Free Base)

    114. Sertraline Hydrochloride, British Pharmacopoeia (bp) Reference Standard

    115. Sertraline Hydrochloride, European Pharmacopoeia (ep) Reference Standard

    116. (1s,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl(methyl)amine Hydrochloride

    117. (1s,4s)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-naphthalenaminehydrochloride

    118. (1s,4s)-4-(3,4-dichlorophenyl)-n-methyl-1,2,3,4-tetrahydronaphthalen-1-amine Hcl

    119. Sertraline For Peak Identification, European Pharmacopoeia (ep) Reference Standard

    120. Sertraline For System Suitability, European Pharmacopoeia (ep) Reference Standard

    121. Sertraline Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    122. (1 S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-naphathalenamine Hydrochloride

    123. (1s,4s)-4-(3,4-dichlorophenyl)-1,2, 3,4-tetrahydro-n-methyl-1-naphthalenamine Hydrochloride

    124. (1s-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-naphathalenamine Hydrochloride

    125. [(1s,4s)-4-(3,4-dichloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]-methyl-amine Hydrochloride

    126. 1-naphthalenamine,?4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-, (1s,4s)-, Hydrochloride?(1:1)

    127. Rac-sertraline Hydrochloride ((1rs,4rs)-4-(3,4-dichlorophenyl)-n-methyl-1,2,3,4-tetrahydronaphthalen-1-amine Hydrochloride)

    128. Sertraline Hydrochloride Racemic Mixture, United States Pharmacopeia (usp) Reference Standard

    129. Sertraline Hydrochloride Solution, 1.0 Mg/ml In Methanol (as Free Base), Ampule Of 1 Ml, Certified Reference Material

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 342.7 g/mol
    Molecular Formula C17H18Cl3N
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count1
    Rotatable Bond Count2
    Exact Mass341.050483 g/mol
    Monoisotopic Mass341.050483 g/mol
    Topological Polar Surface Area12 Ų
    Heavy Atom Count21
    Formal Charge0
    Complexity322
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 4  
    Drug NameSertraline hydrochloride
    PubMed HealthSertraline (By mouth)
    Drug ClassesAntidepressant, Central Nervous System Agent
    Drug LabelSertraline is a selective serotonin reuptake inhibitor (SSRI) for oral administration. It has a molecular weight of 342.7. Sertraline hydrochloride has the following chemical name: (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphtha...
    Active IngredientSertraline hydrochloride
    Dosage FormTablet; Concentrate
    Routeoral; Oral
    Strengtheq 100mg base; 200mg; eq 50mg base; 150mg; eq 150mg base; eq 200mg base; eq 20mg base/ml; eq 25mg base
    Market StatusTentative Approval; Prescription
    CompanyMylan Pharms; Wockhardt; Ranbaxy; Sun Pharm Inds (in); Teva; Apotex; Aurobindo Pharma; Torrent Pharms; Lupin; Prosam Labs; Invagen Pharms; Cipla; Hikma Pharms; Watson Labs; Austarpharma; Zydus Pharms Usa; Mylan

    2 of 4  
    Drug NameZoloft
    Drug LabelZOLOFT (sertraline hydrochloride) is a selective serotonin reuptake inhibitor (SSRI) for oral administration. It has a molecular weight of 342.7. Sertraline hydrochloride has the following chemical name: (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...
    Active IngredientSertraline hydrochloride
    Dosage FormTablet; Concentrate
    RouteOral
    Strengtheq 100mg base; eq 50mg base; eq 20mg base/ml; eq 25mg base
    Market StatusPrescription
    CompanyPfizer

    3 of 4  
    Drug NameSertraline hydrochloride
    PubMed HealthSertraline (By mouth)
    Drug ClassesAntidepressant, Central Nervous System Agent
    Drug LabelSertraline is a selective serotonin reuptake inhibitor (SSRI) for oral administration. It has a molecular weight of 342.7. Sertraline hydrochloride has the following chemical name: (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphtha...
    Active IngredientSertraline hydrochloride
    Dosage FormTablet; Concentrate
    Routeoral; Oral
    Strengtheq 100mg base; 200mg; eq 50mg base; 150mg; eq 150mg base; eq 200mg base; eq 20mg base/ml; eq 25mg base
    Market StatusTentative Approval; Prescription
    CompanyMylan Pharms; Wockhardt; Ranbaxy; Sun Pharm Inds (in); Teva; Apotex; Aurobindo Pharma; Torrent Pharms; Lupin; Prosam Labs; Invagen Pharms; Cipla; Hikma Pharms; Watson Labs; Austarpharma; Zydus Pharms Usa; Mylan

    4 of 4  
    Drug NameZoloft
    Drug LabelZOLOFT (sertraline hydrochloride) is a selective serotonin reuptake inhibitor (SSRI) for oral administration. It has a molecular weight of 342.7. Sertraline hydrochloride has the following chemical name: (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...
    Active IngredientSertraline hydrochloride
    Dosage FormTablet; Concentrate
    RouteOral
    Strengtheq 100mg base; eq 50mg base; eq 20mg base/ml; eq 25mg base
    Market StatusPrescription
    CompanyPfizer

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Selective Serotonin Reuptake Inhibitors

    Compounds that specifically inhibit the reuptake of serotonin in the brain. (See all compounds classified as Selective Serotonin Reuptake Inhibitors.)

    Antidepressive Agents

    Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Serotonin Reuptake Inhibitor [EPC]; Serotonin Uptake Inhibitors [MoA]; Cytochrome P450 2D6 Inhibitors [MoA]; Serotonin Reuptake Inhibitor [EPC]

    API Reference Price

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HDSERNF004,","address":"ACME PLAZA, ANDHERI KURLA ROAD,","city":"MUMBAI, MAHARASHTRA.","supplier":"ALKALOIDA CHEMICAL COMPANY ZRT","supplierCountry":"HUNGARY","foreign_port":"BUDAPEST","customer":"SUN PHARMACEUTICAL INDUSTRIES LIMITED SEZ UNIT-I","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"180","totalValueFC":"17587.8","currency":"USD","unitRateINR":"14472","date":"04-Oct-2022","totalValueINR":"1447200","totalValueInUsd":"17587.8","indian_port":"Ranbaxy SEZ\/Mohali","hs_no":"29214990","bill_no":"1000080","productDescription":"API","marketType":"REGULATED MARKET","country":"HUNGARY","selfForZScoreResived":"Pharma Grade","supplierPort":"BUDAPEST","supplierAddress":"N\/A","customerAddress":"ACME PLAZA, ANDHERI KURLA ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1666463400,"product":"SERTRALINE HYDROCHLORIDE (REJECTED GOODS VIDE SB NO-3581682DT-18-08-2022)","address":"PLOT NO.2, MAITRIVIHAR BEHIND MAITRIVANAM, AMEERPET","city":"HYDERABAD","supplier":"TOWA PHARMACEUTICAL COLTD","supplierCountry":"INDIA","foreign_port":"NA","customer":"AUROBINDO PHARMA LTD","customerCountry":"INDIA","quantity":"270.18","actualQuantity":"270.18","unit":"KGS","unitRateFc":"650","totalValueFC":"183815","currency":"USD","unitRateINR":"55981.5","date":"23-Oct-2022","totalValueINR":"15125075.92","totalValueInUsd":"183815","indian_port":"HYDERABAD AIR","hs_no":"29213090","bill_no":"3014716","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"PLOT NO.2, MAITRIVIHAR BEHIND MAITRIVANAM, AMEERPET"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1668969000,"product":"SERTRALINE HYDROCHLORIDE (REJECTED GOODS VIDE SB NO-3581642DT-18-08-2022)","address":"PLOT NO.2, MAITRIVIHAR BEHIND MAITRIVANAM, AMEERPET","city":"HYDERABAD","supplier":"AUROBINDO PHARMA JAPAN KK","supplierCountry":"INDIA","foreign_port":"NA","customer":"AUROBINDO PHARMA LTD","customerCountry":"INDIA","quantity":"278.92","actualQuantity":"278.92","unit":"KGS","unitRateFc":"37720","totalValueFC":"80530.5","currency":"JPY","unitRateINR":"23563.4","date":"21-Nov-2022","totalValueINR":"6572309.13","totalValueInUsd":"80530.5","indian_port":"HYDERABAD AIR","hs_no":"29213090","bill_no":"3403830","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"PLOT NO.2, MAITRIVIHAR BEHIND MAITRIVANAM, AMEERPET"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1671561000,"product":"SERTRALINE HYDROCHLORIDE, (BATCH NO: HDSERNF004","address":"ACME PLAZA, ANDHERI KURLA ROAD,","city":"MUMBAI, MAHARASHTRA.","supplier":"ALKALOIDA CHEMICAL COMPANY ZRT","supplierCountry":"HUNGARY","foreign_port":"BUDAPEST","customer":"SUN PHARMACEUTICAL INDUSTRIES LIMITED SEZ UNIT-I","customerCountry":"INDIA","quantity":"40.00","actualQuantity":"40","unit":"KGS","unitRateFc":"180","totalValueFC":"7299.9","currency":"USD","unitRateINR":"15039","date":"21-Dec-2022","totalValueINR":"601560","totalValueInUsd":"7299.9","indian_port":"Ranbaxy SEZ\/Mohali","hs_no":"29214990","bill_no":"1000093","productDescription":"API","marketType":"REGULATED MARKET","country":"HUNGARY","selfForZScoreResived":"Pharma Grade","supplierPort":"BUDAPEST","supplierAddress":"4440 TISZAVASVARI, KABAY JANOS U.29 ., Hungary Hungary","customerAddress":"ACME PLAZA, ANDHERI KURLA ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1733250600,"product":"REIMPORT OF SERTRALINE HYDROCHLORIDE USP (BATCH NO.SET401123CD-I)(FOC)","address":"1, SHANKAR BHAVAN, FRENCH BRIDGE,","city":"MUMBAI","supplier":"BUSICOM CO LTD","supplierCountry":"INDIA","foreign_port":"BANGKOK","customer":"INNOREX PHARMACEUTICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"225.00","actualQuantity":"225","unit":"KGS","unitRateFc":"105.5","totalValueFC":"24823.8","currency":"USD","unitRateINR":"9374.4","date":"04-Dec-2024","totalValueINR":"2109250.02","totalValueInUsd":"24823.8","indian_port":"Bombay Air","hs_no":"29214590","bill_no":"7043141","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"BANGKOK","supplierAddress":"23 SUKHUMVIT 62 YAEK 4 (SOI TAT PRING). SUKHUMVIT ROAD, PRAKANONG TAI, PRAKANONG,BANGKOK 10 THAILAND","customerAddress":"1, SHANKAR BHAVAN, FRENCH BRIDGE,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1741199400,"product":"SERTRALINE HYDROCHLORIDE (REJECTED AND RE-IMPORTED MATERIAL,EXPORTED VIDE SB NO -2762479 DT-27-JUL-2023,BATCH-SRH0170523SERTRALINE HYDEROCHLORIDE","address":"FLAT NO.404 TO 406,4TH FLOOR,VIJAY","city":"HYDERABAD.AP","supplier":"CHEMO AG VIENNA LUGANO BRANCH","supplierCountry":"SPAIN","foreign_port":"BARCELONA","customer":"NOSCH LABS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"299.41","actualQuantity":"299.409","unit":"KGS","unitRateFc":"133.7","totalValueFC":"40559.3","currency":"N\/A","unitRateINR":"11733.6","date":"06-Mar-2025","totalValueINR":"3513148.66","totalValueInUsd":"40559.3","indian_port":"Hyderabad ICD","hs_no":"29322090","bill_no":"8738857","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"BARCELONA","supplierAddress":"VIA F.PELLI, 17,P.O. BOX, LUGANO - 6901, , Switzerland SDNF Switzerland","customerAddress":"FLAT NO.404 TO 406,4TH FLOOR,VIJAY"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1744050600,"product":"SERTRALINE HYDROCHLORIDE PH.EUR","address":"7-2-A2, HETERO CORPORATE,","city":"HYDERABAD-A.P.","supplier":"HETERO DRUGS LTD UNIT IX","supplierCountry":"INDIA","foreign_port":"HIPL SEZ","customer":"HETERO DRUGS LIMITED","customerCountry":"INDIA","quantity":"505.67","actualQuantity":"505.67","unit":"KGS","unitRateFc":"100.5","totalValueFC":"51393","currency":"USD","unitRateINR":"8700","date":"08-Apr-2025","totalValueINR":"4399329","totalValueInUsd":"51393","indian_port":"Vizag-HIPL SEZ","hs_no":"29214990","bill_no":"9370491","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"HIPL SEZ","supplierAddress":"PLOT NO 1 HETERO INFRASTRUCTURE SEZ N.NARASAPURAM (V), NAKKAPALLY SDNF India","customerAddress":"7-2-A2, HETERO CORPORATE,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1744050600,"product":"SERTRALINE HYDROCHLORIDE PH.EUR","address":"7-2-A2, HETERO CORPORATE,","city":"HYDERABAD-A.P.","supplier":"HETERO DRUGS LTD UNIT IX","supplierCountry":"INDIA","foreign_port":"HIPL SEZ","customer":"HETERO DRUGS LIMITED","customerCountry":"INDIA","quantity":"1417.30","actualQuantity":"1417.3","unit":"KGS","unitRateFc":"100.5","totalValueFC":"144045","currency":"USD","unitRateINR":"8700","date":"08-Apr-2025","totalValueINR":"12330510","totalValueInUsd":"144045","indian_port":"Vizag-HIPL SEZ","hs_no":"29214990","bill_no":"9357839","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"HIPL SEZ","supplierAddress":"PLOT NO 1 HETERO INFRASTRUCTURE SEZ N.NARASAPURAM (V), NAKKAPALLY SDNF India","customerAddress":"7-2-A2, HETERO CORPORATE,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1745001000,"product":"SERTRALINE HYDROCHLORIDE (FORM-II), USP SERTRALINE HYDROCHLORIDE (FORM-II), USP","address":"MUMBAI CENTRAL,","city":"MUMBAI, MAHARASHTRA.","supplier":"INVAGEN PHARMACEUTICALS INC","supplierCountry":"UNITED STATES","foreign_port":"NEW YORK - JOHN F. K","customer":"CIPLA LIMITED","customerCountry":"INDIA","quantity":"5025.45","actualQuantity":"5025.453","unit":"KGS","unitRateFc":"126","totalValueFC":"639261.1","currency":"USD","unitRateINR":"10888.9","date":"19-Apr-2025","totalValueINR":"54721887.56","totalValueInUsd":"639261.1","indian_port":"Bombay Air","hs_no":"29214990","bill_no":"9586266","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NEW YORK - JOHN F. K","supplierAddress":"7 OSER AVE, HAUPPAUGE NY-11788 SDNF UNITED STATES","customerAddress":"MUMBAI CENTRAL,"}]
    04-Jan-2022
    30-Apr-2025
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    DRUG PRODUCT COMPOSITIONS

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    DOSAGE - TABLET;ORAL - EQ 100MG BASE

    USFDA APPLICATION NUMBER - 19839

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    DOSAGE - TABLET;ORAL - EQ 150MG BASE **Federa...DOSAGE - TABLET;ORAL - EQ 150MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 19839

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    DOSAGE - TABLET;ORAL - EQ 200MG BASE **Federa...DOSAGE - TABLET;ORAL - EQ 200MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 19839

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    DOSAGE - TABLET;ORAL - EQ 25MG BASE

    USFDA APPLICATION NUMBER - 19839

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    DOSAGE - TABLET;ORAL - EQ 50MG BASE

    USFDA APPLICATION NUMBER - 19839

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    ABOUT THIS PAGE

    Looking for 79559-97-0 / Sertraline Hydrochloride API manufacturers, exporters & distributors?

    Sertraline Hydrochloride manufacturers, exporters & distributors 1

    95

    PharmaCompass offers a list of Sertraline Hydrochloride API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Sertraline Hydrochloride manufacturer or Sertraline Hydrochloride supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Sertraline Hydrochloride manufacturer or Sertraline Hydrochloride supplier.

    PharmaCompass also assists you with knowing the Sertraline Hydrochloride API Price utilized in the formulation of products. Sertraline Hydrochloride API Price is not always fixed or binding as the Sertraline Hydrochloride Price is obtained through a variety of data sources. The Sertraline Hydrochloride Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Sertraline Hydrochloride

    Synonyms

    79559-97-0, Sertraline hcl, Zoloft, Gladem, Lustral, Serad

    Cas Number

    79559-97-0

    Unique Ingredient Identifier (UNII)

    UTI8907Y6X

    About Sertraline Hydrochloride

    A selective serotonin uptake inhibitor that is used in the treatment of depression.

    Gladem Manufacturers

    A Gladem manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Gladem, including repackagers and relabelers. The FDA regulates Gladem manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Gladem API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Gladem manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Gladem Suppliers

    A Gladem supplier is an individual or a company that provides Gladem active pharmaceutical ingredient (API) or Gladem finished formulations upon request. The Gladem suppliers may include Gladem API manufacturers, exporters, distributors and traders.

    click here to find a list of Gladem suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Gladem USDMF

    A Gladem DMF (Drug Master File) is a document detailing the whole manufacturing process of Gladem active pharmaceutical ingredient (API) in detail. Different forms of Gladem DMFs exist exist since differing nations have different regulations, such as Gladem USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Gladem DMF submitted to regulatory agencies in the US is known as a USDMF. Gladem USDMF includes data on Gladem's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Gladem USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Gladem suppliers with USDMF on PharmaCompass.

    Gladem JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Gladem Drug Master File in Japan (Gladem JDMF) empowers Gladem API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Gladem JDMF during the approval evaluation for pharmaceutical products. At the time of Gladem JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Gladem suppliers with JDMF on PharmaCompass.

    Gladem KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Gladem Drug Master File in Korea (Gladem KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Gladem. The MFDS reviews the Gladem KDMF as part of the drug registration process and uses the information provided in the Gladem KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Gladem KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Gladem API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Gladem suppliers with KDMF on PharmaCompass.

    Gladem CEP

    A Gladem CEP of the European Pharmacopoeia monograph is often referred to as a Gladem Certificate of Suitability (COS). The purpose of a Gladem CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Gladem EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Gladem to their clients by showing that a Gladem CEP has been issued for it. The manufacturer submits a Gladem CEP (COS) as part of the market authorization procedure, and it takes on the role of a Gladem CEP holder for the record. Additionally, the data presented in the Gladem CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Gladem DMF.

    A Gladem CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Gladem CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Gladem suppliers with CEP (COS) on PharmaCompass.

    Gladem WC

    A Gladem written confirmation (Gladem WC) is an official document issued by a regulatory agency to a Gladem manufacturer, verifying that the manufacturing facility of a Gladem active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Gladem APIs or Gladem finished pharmaceutical products to another nation, regulatory agencies frequently require a Gladem WC (written confirmation) as part of the regulatory process.

    click here to find a list of Gladem suppliers with Written Confirmation (WC) on PharmaCompass.

    Gladem NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Gladem as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Gladem API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Gladem as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Gladem and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Gladem NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Gladem suppliers with NDC on PharmaCompass.

    Gladem GMP

    Gladem Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Gladem GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Gladem GMP manufacturer or Gladem GMP API supplier for your needs.

    Gladem CoA

    A Gladem CoA (Certificate of Analysis) is a formal document that attests to Gladem's compliance with Gladem specifications and serves as a tool for batch-level quality control.

    Gladem CoA mostly includes findings from lab analyses of a specific batch. For each Gladem CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Gladem may be tested according to a variety of international standards, such as European Pharmacopoeia (Gladem EP), Gladem JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Gladem USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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