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Chemistry

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Also known as: 1416992-39-6, Gc376, Gc-376, H1nmj5xdg5, Sodium (2s)-2-((s)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate, (betas)-alpha-hydroxy-beta-[[(2s)-4-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]pentyl]amino]-2-oxo-3-pyrrolidinepropanesulfonic acid sodium salt
Molecular Formula
C21H30N3NaO8S
Molecular Weight
507.5  g/mol
InChI Key
BSPJDKCMFIPBAW-JPBGFCRCSA-M
FDA UNII
H1NMJ5XDG5

GC376
1 2D Structure

GC376

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;(2S)-1-hydroxy-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate
2.1.2 InChI
InChI=1S/C21H31N3O8S.Na/c1-13(2)10-16(24-21(28)32-12-14-6-4-3-5-7-14)19(26)23-17(20(27)33(29,30)31)11-15-8-9-22-18(15)25;/h3-7,13,15-17,20,27H,8-12H2,1-2H3,(H,22,25)(H,23,26)(H,24,28)(H,29,30,31);/q;+1/p-1/t15?,16-,17-,20?;/m0./s1
2.1.3 InChI Key
BSPJDKCMFIPBAW-JPBGFCRCSA-M
2.1.4 Canonical SMILES
CC(C)CC(C(=O)NC(CC1CCNC1=O)C(O)S(=O)(=O)[O-])NC(=O)OCC2=CC=CC=C2.[Na+]
2.1.5 Isomeric SMILES
CC(C)C[C@@H](C(=O)N[C@@H](CC1CCNC1=O)C(O)S(=O)(=O)[O-])NC(=O)OCC2=CC=CC=C2.[Na+]
2.2 Other Identifiers
2.2.1 UNII
H1NMJ5XDG5
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (beta S)-alpha-hydroxy-beta-(((2s)-4-methyl-1-oxo-2-(((phenylmethoxy)carbonyl)amino)pentyl)amino)-2-oxo-3-pyrrolidinepropanesulfonic Acid

2. (beta S)-alpha-hydroxy-beta-(((2s)-4-methyl-1-oxo-2-(((phenylmethoxy)carbonyl)amino)pentyl)amino)-2-oxo-3-pyrrolidinepropanesulfonic Acid (1:1) Sodium Salt

3. Gc 376

4. Gc-376

5. Gc-376 Free Acid

6. Gc376

7. Sodium (2s)-2-((s)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate

2.3.2 Depositor-Supplied Synonyms

1. 1416992-39-6

2. Gc376

3. Gc-376

4. H1nmj5xdg5

5. Sodium (2s)-2-((s)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate

6. (betas)-alpha-hydroxy-beta-[[(2s)-4-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]pentyl]amino]-2-oxo-3-pyrrolidinepropanesulfonic Acid Sodium Salt

7. Sodium;(2s)-1-hydroxy-2-[[(2s)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate

8. Unii-h1nmj5xdg5

9. Chembl2315036

10. Dtxsid001028041

11. At23091

12. Cs-6923

13. As-84675

14. Hy-100721

15. A937086

16. 3-pyrrolidinepropanesulfonic Acid, .alpha.-hydroxy-.beta.-(((2s)-4-methyl-1-oxo-2-(((phenylmethoxy)carbonyl)amino)pentyl)amino)-2-oxo-, Sodium Salt (1:1), (.beta.s)-

17. 3-pyrrolidinepropanesulfonic Acid, Alpha-hydroxy-beta-(((2s)-4-methyl-1-oxo-2-(((phenylmethoxy)carbonyl)amino)pentyl)amino)-2-oxo-, Sodium Salt (1:1), (betas)-

18. Sodium (2s)-1-hydroxy-2-[[(2s)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate

19. Sodium (2s)-2-[(2s)-2-{[(benzyloxy)carbonyl]amino}-4-methylpentanamido]-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate

2.4 Create Date
2013-06-10
3 Chemical and Physical Properties
Molecular Weight 507.5 g/mol
Molecular Formula C21H30N3NaO8S
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count8
Rotatable Bond Count12
Exact Mass507.16513038 g/mol
Monoisotopic Mass507.16513038 g/mol
Topological Polar Surface Area182 Ų
Heavy Atom Count34
Formal Charge0
Complexity783
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Protease Inhibitors

Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES). (See all compounds classified as Protease Inhibitors.)


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Looking for 1416992-39-6 / GC376 API manufacturers, exporters & distributors?

GC376 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of GC376 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right GC376 manufacturer or GC376 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred GC376 manufacturer or GC376 supplier.

PharmaCompass also assists you with knowing the GC376 API Price utilized in the formulation of products. GC376 API Price is not always fixed or binding as the GC376 Price is obtained through a variety of data sources. The GC376 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

GC376

Synonyms

1416992-39-6, Gc-376, H1nmj5xdg5, Sodium (2s)-2-((s)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate, (betas)-alpha-hydroxy-beta-[[(2s)-4-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]pentyl]amino]-2-oxo-3-pyrrolidinepropanesulfonic acid sodium salt, Sodium;(2s)-1-hydroxy-2-[[(2s)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate

Cas Number

1416992-39-6

Unique Ingredient Identifier (UNII)

H1NMJ5XDG5

GC376 Manufacturers

A GC376 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of GC376, including repackagers and relabelers. The FDA regulates GC376 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. GC376 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

GC376 Suppliers

A GC376 supplier is an individual or a company that provides GC376 active pharmaceutical ingredient (API) or GC376 finished formulations upon request. The GC376 suppliers may include GC376 API manufacturers, exporters, distributors and traders.

GC376 GMP

GC376 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of GC376 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right GC376 GMP manufacturer or GC376 GMP API supplier for your needs.

GC376 CoA

A GC376 CoA (Certificate of Analysis) is a formal document that attests to GC376's compliance with GC376 specifications and serves as a tool for batch-level quality control.

GC376 CoA mostly includes findings from lab analyses of a specific batch. For each GC376 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

GC376 may be tested according to a variety of international standards, such as European Pharmacopoeia (GC376 EP), GC376 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (GC376 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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