Find G207 manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Wf8nwa83re, G 207, G 207 [who-dd], G207, G-207, 80156-87-2
Molecular Formula
C25H28N4O
Molecular Weight
400.5  g/mol
InChI Key
ZUGKFNYCFBDWIO-UHFFFAOYSA-N
FDA UNII
WF8NWA83RE

G207
G207 is cancer-killing viruses, so-called oncolytic viruses, for the treatment of various forms of cancer developed by MediGene AG. These viruses are specific herpes simplex viruses, or HSVs, generally known as the cause of cold sores. MediGene uses these viruses, however, in a modified and "disarmed" form in order to make them utilizable as a therapeutic agent in humans.
1 2D Structure

G207

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(4-butylphenyl)-[4-[(4-propoxyphenyl)diazenyl]phenyl]diazene
2.1.2 InChI
InChI=1S/C25H28N4O/c1-3-5-6-20-7-9-21(10-8-20)26-27-22-11-13-23(14-12-22)28-29-24-15-17-25(18-16-24)30-19-4-2/h7-18H,3-6,19H2,1-2H3
2.1.3 InChI Key
ZUGKFNYCFBDWIO-UHFFFAOYSA-N
2.2 Other Identifiers
2.2.1 UNII
WF8NWA83RE
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Wf8nwa83re

2. G 207

3. G 207 [who-dd]

4. G207

5. G-207

6. 80156-87-2

7. 2136340-90-2

8. 162320-00-5

9. Unii-wf8nwa83re

10. Schembl12425118

11. Schembl24849964

12. Dtxsid70612659

13. Zugkfnycfbdwio-uhfffaoysa-n

14. (e)-1-(4-butylphenyl)-2-{4-[(e)-(4-propoxyphenyl)diazenyl]phenyl}diazene

2.4 Create Date
2007-12-05
3 Chemical and Physical Properties
Molecular Weight 400.5 g/mol
Molecular Formula C25H28N4O
XLogP38.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count10
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area58.7
Heavy Atom Count30
Formal Charge0
Complexity499
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Investigated for use/treatment in brain cancer.


5 Pharmacology and Biochemistry
5.1 Mechanism of Action

G207, Cancer killing viruses are modified to make them utilizable as a therapeutic agent in human by switching off certain genes that normally enable the virus to multiply in healthy cells, which would destroy these cells. As a result of this genetic modification, the HSVs are able to reproduce in tumor cells solely, since only this offer an environment that compensates for the loss of the removed viral genes. Consequently, the virus is able to replicate in the tumor cells, selectively destroying them without harming healthy tissue.


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Looking for 2136340-90-2 / G207 API manufacturers, exporters & distributors?

G207 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of G207 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right G207 manufacturer or G207 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred G207 manufacturer or G207 supplier.

PharmaCompass also assists you with knowing the G207 API Price utilized in the formulation of products. G207 API Price is not always fixed or binding as the G207 Price is obtained through a variety of data sources. The G207 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

G207

Synonyms

Wf8nwa83re, G 207, G 207 [who-dd], G-207, 80156-87-2, 2136340-90-2

Cas Number

2136340-90-2

Unique Ingredient Identifier (UNII)

WF8NWA83RE

About G207

G207 is cancer-killing viruses, so-called oncolytic viruses, for the treatment of various forms of cancer developed by MediGene AG. These viruses are specific herpes simplex viruses, or HSVs, generally known as the cause of cold sores. MediGene uses these viruses, however, in a modified and "disarmed" form in order to make them utilizable as a therapeutic agent in humans.

G207 Manufacturers

A G207 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of G207, including repackagers and relabelers. The FDA regulates G207 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. G207 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

G207 Suppliers

A G207 supplier is an individual or a company that provides G207 active pharmaceutical ingredient (API) or G207 finished formulations upon request. The G207 suppliers may include G207 API manufacturers, exporters, distributors and traders.

G207 GMP

G207 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of G207 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right G207 GMP manufacturer or G207 GMP API supplier for your needs.

G207 CoA

A G207 CoA (Certificate of Analysis) is a formal document that attests to G207's compliance with G207 specifications and serves as a tool for batch-level quality control.

G207 CoA mostly includes findings from lab analyses of a specific batch. For each G207 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

G207 may be tested according to a variety of international standards, such as European Pharmacopoeia (G207 EP), G207 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (G207 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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