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1. Evt 201
2. Evt-201
3. Evt201
1. Evt-201
2. 308239-86-3
3. 6j8af7cle4
4. Unii-6j8af7cle4
5. Evt201
6. Schembl3088188
7. Dtxsid301032055
8. Q19597232
9. 6h-imidazo(1,5-a)(1,4)benzodiazepin-6-one, 7-chloro-3-(5-((dimethylamino)methyl)-1,2,4-oxadiazol-3-yl)-4,5-dihydro-5-methyl-
10. 7-chloro-3-(5-dimethylaminomethyl-[1,2,4]oxadiazol-3-yl)-5-methyl-4,5-dihydro-imidazo[1,5-a][1,4]benzodiazepin-6-one
| Molecular Weight | 372.8 g/mol |
|---|---|
| Molecular Formula | C17H17ClN6O2 |
| XLogP3 | 1.2 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 3 |
| Exact Mass | 372.1101515 g/mol |
| Monoisotopic Mass | 372.1101515 g/mol |
| Topological Polar Surface Area | 80.3 Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 537 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Investigated for use/treatment in insomnia.
In two Phase I/II studies using the traffic noise model of insomnia in healthy male volunteers, EVT 201 significantly reduced "wake after sleep onset" (WASO) while significantly increasing "total sleep time" (TST) and quality of sleep with no subjective residual effects. The compound was well tolerated without significant adverse events.
EVT 201 is a partial positive allosteric modulator (pPAM) of the GABAA receptor complex and consequently works through a proven pathway in the treatment of insomnia. However, EVT 201s partial agonist activity gives it a differentiated pre-clinical profile and mechanism of action compared to many currently marketed sleep-promoting agents.
ABOUT THIS PAGE
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PharmaCompass offers a list of EVT-201 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right EVT-201 manufacturer or EVT-201 supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred EVT-201 manufacturer or EVT-201 supplier.
PharmaCompass also assists you with knowing the EVT-201 API Price utilized in the formulation of products. EVT-201 API Price is not always fixed or binding as the EVT-201 Price is obtained through a variety of data sources. The EVT-201 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A EVT 201 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of EVT 201, including repackagers and relabelers. The FDA regulates EVT 201 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. EVT 201 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A EVT 201 supplier is an individual or a company that provides EVT 201 active pharmaceutical ingredient (API) or EVT 201 finished formulations upon request. The EVT 201 suppliers may include EVT 201 API manufacturers, exporters, distributors and traders.
EVT 201 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of EVT 201 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right EVT 201 GMP manufacturer or EVT 201 GMP API supplier for your needs.
A EVT 201 CoA (Certificate of Analysis) is a formal document that attests to EVT 201's compliance with EVT 201 specifications and serves as a tool for batch-level quality control.
EVT 201 CoA mostly includes findings from lab analyses of a specific batch. For each EVT 201 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
EVT 201 may be tested according to a variety of international standards, such as European Pharmacopoeia (EVT 201 EP), EVT 201 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (EVT 201 USP).
