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Chemistry

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Also known as: Elismetrep [inn], Elismetrep [usan], Kib8v5ur7d, Mt-8554, 1400699-64-0, 4-(((4-cyclopropyl-3-isoquinolinyl)((4-(trifluoromethoxy)phenyl)methyl)amino)sulfonyl)benzoic acid
Molecular Formula
C27H21F3N2O5S
Molecular Weight
542.5  g/mol
InChI Key
CWEFDWIKLABKBX-UHFFFAOYSA-N
FDA UNII
KIB8V5UR7D

Elismetrep
Elismetrep is under investigation in clinical trial NCT02429102 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of MT-8554 in Healthy Subjects).
1 2D Structure

Elismetrep

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[(4-cyclopropylisoquinolin-3-yl)-[[4-(trifluoromethoxy)phenyl]methyl]sulfamoyl]benzoic acid
2.1.2 InChI
InChI=1S/C27H21F3N2O5S/c28-27(29,30)37-21-11-5-17(6-12-21)16-32(38(35,36)22-13-9-19(10-14-22)26(33)34)25-24(18-7-8-18)23-4-2-1-3-20(23)15-31-25/h1-6,9-15,18H,7-8,16H2,(H,33,34)
2.1.3 InChI Key
CWEFDWIKLABKBX-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CC1C2=C(N=CC3=CC=CC=C32)N(CC4=CC=C(C=C4)OC(F)(F)F)S(=O)(=O)C5=CC=C(C=C5)C(=O)O
2.2 Other Identifiers
2.2.1 UNII
KIB8V5UR7D
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Elismetrep [inn]

2. Elismetrep [usan]

3. Kib8v5ur7d

4. Mt-8554

5. 1400699-64-0

6. 4-(((4-cyclopropyl-3-isoquinolinyl)((4-(trifluoromethoxy)phenyl)methyl)amino)sulfonyl)benzoic Acid

7. Benzoic Acid, 4-(((4-cyclopropyl-3-isoquinolinyl)((4-(trifluoromethoxy)phenyl)methyl)amino)sulfonyl)-

8. Elismetrep (usan/inn)

9. Elismetrep [usan:inn]

10. Unii-kib8v5ur7d

11. Gtpl9774

12. Chembl3682589

13. Schembl12490163

14. Bdbm151677

15. Bcp30294

16. Who 10708

17. Db15287

18. Example 104 [wo2012124825]

19. D11448

20. Us8987445, 104

21. 4-((4-cyclopropylisoquinolin-3-yl) (4-(trifluoromethoxy) Benzyl) Sulfamoyl) Benzoic Acid

22. 4-[(4-cyclopropylisoquinolin-3-yl)-[[4-(trifluoromethoxy)phenyl]methyl]sulfamoyl]benzoic Acid

2.4 Create Date
2012-10-30
3 Chemical and Physical Properties
Molecular Weight 542.5 g/mol
Molecular Formula C27H21F3N2O5S
XLogP36.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count10
Rotatable Bond Count8
Exact Mass542.11232743 g/mol
Monoisotopic Mass542.11232743 g/mol
Topological Polar Surface Area105 Ų
Heavy Atom Count38
Formal Charge0
Complexity922
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 1400699-64-0 / Elismetrep API manufacturers, exporters & distributors?

Elismetrep manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Elismetrep API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Elismetrep manufacturer or Elismetrep supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Elismetrep manufacturer or Elismetrep supplier.

PharmaCompass also assists you with knowing the Elismetrep API Price utilized in the formulation of products. Elismetrep API Price is not always fixed or binding as the Elismetrep Price is obtained through a variety of data sources. The Elismetrep Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Elismetrep

Synonyms

Elismetrep [inn], Elismetrep [usan], Kib8v5ur7d, Mt-8554, 1400699-64-0, 4-(((4-cyclopropyl-3-isoquinolinyl)((4-(trifluoromethoxy)phenyl)methyl)amino)sulfonyl)benzoic acid

Cas Number

1400699-64-0

Unique Ingredient Identifier (UNII)

KIB8V5UR7D

About Elismetrep

Elismetrep is under investigation in clinical trial NCT02429102 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of MT-8554 in Healthy Subjects).

Elismetrep Manufacturers

A Elismetrep manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Elismetrep, including repackagers and relabelers. The FDA regulates Elismetrep manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Elismetrep API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Elismetrep Suppliers

A Elismetrep supplier is an individual or a company that provides Elismetrep active pharmaceutical ingredient (API) or Elismetrep finished formulations upon request. The Elismetrep suppliers may include Elismetrep API manufacturers, exporters, distributors and traders.

Elismetrep GMP

Elismetrep Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Elismetrep GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Elismetrep GMP manufacturer or Elismetrep GMP API supplier for your needs.

Elismetrep CoA

A Elismetrep CoA (Certificate of Analysis) is a formal document that attests to Elismetrep's compliance with Elismetrep specifications and serves as a tool for batch-level quality control.

Elismetrep CoA mostly includes findings from lab analyses of a specific batch. For each Elismetrep CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Elismetrep may be tested according to a variety of international standards, such as European Pharmacopoeia (Elismetrep EP), Elismetrep JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Elismetrep USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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