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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 2505078-08-8, Blu-263, 6fbm4cp6rk, Blu263, Exampl4 4 [wo2020210293a1], 1h-pyrazole-1-ethanol, 4-(4-(4-(5-((1s)-1-amino-1-(4-fluorophenyl)ethyl)-2-pyrimidinyl)-1-piperazinyl)pyrrolo(2,1-f)(1,2,4)triazin-6-yl)-
Molecular Formula
C27H29FN10O
Molecular Weight
528.6  g/mol
InChI Key
IPMARPMXSFFZFG-MHZLTWQESA-N
FDA UNII
6FBM4CP6RK

Elenestinib
ELENESTINIB is a small molecule drug with a maximum clinical trial phase of II (across all indications) and has 2 investigational indications.
1 2D Structure

Elenestinib

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[4-[4-[4-[5-[(1S)-1-amino-1-(4-fluorophenyl)ethyl]pyrimidin-2-yl]piperazin-1-yl]pyrrolo[2,1-f][1,2,4]triazin-6-yl]pyrazol-1-yl]ethanol
2.1.2 InChI
InChI=1S/C27H29FN10O/c1-27(29,21-2-4-23(28)5-3-21)22-14-30-26(31-15-22)36-8-6-35(7-9-36)25-24-12-19(17-38(24)34-18-32-25)20-13-33-37(16-20)10-11-39/h2-5,12-18,39H,6-11,29H2,1H3/t27-/m0/s1
2.1.3 InChI Key
IPMARPMXSFFZFG-MHZLTWQESA-N
2.2 Other Identifiers
2.2.1 UNII
6FBM4CP6RK
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 2505078-08-8

2. Blu-263

3. 6fbm4cp6rk

4. Blu263

5. Exampl4 4 [wo2020210293a1]

6. 1h-pyrazole-1-ethanol, 4-(4-(4-(5-((1s)-1-amino-1-(4-fluorophenyl)ethyl)-2-pyrimidinyl)-1-piperazinyl)pyrrolo(2,1-f)(1,2,4)triazin-6-yl)-

7. 2-[4-[4-[4-[5-[(1s)-1-amino-1-(4-fluorophenyl)ethyl]pyrimidin-2-yl]piperazin-1-yl]pyrrolo[2,1-f][1,2,4]triazin-6-yl]pyrazol-1-yl]ethanol

8. 1h-pyrazole-1-ethanol, 4-[4-[4-[5-[(1s)-1-amino-1-(4-fluorophenyl)ethyl]-2-pyrimidinyl]-1-piperazinyl]pyrrolo[2,1-f][1,2,4]triazin-6-yl]-

9. 4-[4-[4-[5-[(1s)-1-amino-1-(4-fluorophenyl)ethyl]-2-pyrimidinyl]-1-piperazinyl]pyrrolo[2,1-f][1,2,4]triazin-6-yl]-1h-pyrazole-1-ethanol

10. Exampl4 4 (wo2020210293a1)

11. 2-(4-(4-(4-(5-((1s)-1-amino-1-(4-fluorophenyl)ethyl)pyrimidin-2-yl)piperazin-1-yl)pyrrolo(2,1-f)(1,2,4)triazin-6-yl)-1h-pyrazol-1-yl)ethan-1-ol

12. 2-(4-(4-(4-(5-((1s)-1-amino-1-(4-fluorophenyl)ethyl)pyrimidin-2-yl)piperazin-1-yl)pyrrolo(2,1-f)(1,2,4)triazin-6-yl)pyrazol-1-yl)ethanol

13. 2-{4-[4-(4-{5-[(1s)-1-amino-1-(4-fluorophenyl)ethyl]pyrimidin-2-yl}piperazin-1-yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl]-1h-pyrazol-1-yl}ethan-1-ol

14. 4-(4-(4-(5-((1s)-1-amino-1-(4-fluorophenyl)ethyl)-2-pyrimidinyl)-1-piperazinyl)pyrrolo(2,1-f)(1,2,4)triazin-6-yl)-1h-pyrazole-1-ethanol

15. Refchem:136476

16. Blu 263

17. D816v-mutant Kit Inhibitor Blu-263

18. Kit D816v Mutant-selective Inhibitor Blu-263

19. Elenestinib [usan]

20. Unii-6fbm4cp6rk

21. Who 12608

22. Elenestinib (usan)

23. (s)-2-(4-(4-(4-(5-(1-amino-1-(4-fluorophenyl)ethyl)pyrimidin-2-yl)piperazin-1-yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-1h-pyrazol-1-yl)ethan-1-ol

24. (s)-2-(4-(4-(4-(5-(1-amino-1-(4-fluorophenyl)ethyl)pyrimidin-2-yl)piperazin-1-yl)pyrrolo(2,1-f)(1,2,4)triazin-6-yl)-1h-pyrazol-1-yl)ethan-1-ol

25. Elenestinib [inn]

26. Elenestinib(blu-263)

27. Orb1298206

28. Chembl5314552

29. Schembl22527434

30. Gtpl12357

31. Glxc-26842

32. Ex-a4620

33. At32812

34. Ac-37128

35. Da-73060

36. Ms-29783

37. Hy-152839

38. Cs-0641116

39. D12450

40. 2-{4-[4-(4-{5-[(1s)-1-amino-1-(4- Fluorophenyl)ethyl]pyrimidin-2-yl}piperazin-1- Yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl]-1h-pyrazol-1- Yl}ethan-1-ol

2.4 Create Date
2020-12-19
3 Chemical and Physical Properties
Molecular Weight 528.6 g/mol
Molecular Formula C27H29FN10O
XLogP31.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area127
Heavy Atom Count39
Formal Charge0
Complexity789
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 2505078-08-8 / Elenestinib API manufacturers, exporters & distributors?

Elenestinib manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Elenestinib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Elenestinib manufacturer or Elenestinib supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Elenestinib manufacturer or Elenestinib supplier.

API | Excipient name

Elenestinib

Synonyms

2505078-08-8, Blu-263, 6fbm4cp6rk, Blu263, Exampl4 4 [wo2020210293a1], 1h-pyrazole-1-ethanol, 4-(4-(4-(5-((1s)-1-amino-1-(4-fluorophenyl)ethyl)-2-pyrimidinyl)-1-piperazinyl)pyrrolo(2,1-f)(1,2,4)triazin-6-yl)-

Cas Number

2505078-08-8

Unique Ingredient Identifier (UNII)

6FBM4CP6RK

About Elenestinib

ELENESTINIB is a small molecule drug with a maximum clinical trial phase of II (across all indications) and has 2 investigational indications.

Elenestinib Manufacturers

A Elenestinib manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Elenestinib, including repackagers and relabelers. The FDA regulates Elenestinib manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Elenestinib API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Elenestinib Suppliers

A Elenestinib supplier is an individual or a company that provides Elenestinib active pharmaceutical ingredient (API) or Elenestinib finished formulations upon request. The Elenestinib suppliers may include Elenestinib API manufacturers, exporters, distributors and traders.

Elenestinib GMP

Elenestinib Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Elenestinib GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Elenestinib GMP manufacturer or Elenestinib GMP API supplier for your needs.

Elenestinib CoA

A Elenestinib CoA (Certificate of Analysis) is a formal document that attests to Elenestinib's compliance with Elenestinib specifications and serves as a tool for batch-level quality control.

Elenestinib CoA mostly includes findings from lab analyses of a specific batch. For each Elenestinib CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Elenestinib may be tested according to a variety of international standards, such as European Pharmacopoeia (Elenestinib EP), Elenestinib JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Elenestinib USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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