Elbasvir

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

4 API Suppliers, 1 KDMF, 1 NDC API, 4 Listed Suppliers

INTERMEDIATES

8 Suppliers

8 Suppliers

DOSSIERs // Finished Dosage Formulations

3 Dossiers, 1 FDA Orange Book, 1 Europe, 1 Listed Dossiers

RELATED EXCIPIENT COMPANIES

Suppliers, 19 Kerry, 13 SPI Pharma, 13 Roquette, 12 Microlex e.U, 10 Gangwal Healthcare, 10 Sigachi Industries, 9 BASF, 5 DFE Pharma, 5 Gangwal Chemicals, 5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 3 Prachin Chemical, 3 Vasa Pharmachem, 2 Actylis, 2 Ingredion Pharma Solutions, 1 Shijiazhuang Huaxu Pharmaceutical, 1 Boai NKY Pharmaceuticals Ltd, 1 Pharmatrans-Sanaq, 1 DKSH, 1 Huzhou Sunflower Pharmaceutical Co. Ltd, 1 Bioplus Life Sciences, 1 Seqens, 1 Ideal Cures Pvt Ltd, 1 PMC Isochem, 1 Jai Radhe Sales, 1 Pfanstiehl, 1 Alcedo Pharmachem, 1 Nanjing Well Pharmaceutical, 1 Rochem International Inc

EXCIPIENTS BY APPLICATIONS

61 Fillers, Diluents & Binders, 29 Direct Compression, 17 Granulation, 15 Disintegrants & Superdisintegrants, 14 Taste Masking, 13 Co-Processed Excipients, 12 Thickeners and Stabilizers, 12 Lubricants & Glidants, 11 Chewable & Orodispersible Aids, 8 Coating Systems & Additives, 8 Film Formers & Plasticizers, 6 Parenteral, 6 Controlled & Modified Release, 4 Emulsifying Agents, 3 Solubilizers, 2 API Stability Enhancers, 2 Topical, 2 Rheology Modifiers, 1 Surfactant & Foaming Agents

GLOBAL SALES INFORMATION

1 Finished Drug Prices

1 Finished Drug Prices

MARKET PLACE

3 APIs

3 APIs

PATENTS

2 US Patents, 1 US Exclusivities

DIGITAL CONTENT

2 Data Compilations & Company Tracker #PharmaFlow, 32 News

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

Annual Reports

455.00

FDF Market Place

EXCIPIENTS

129

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: Dtxsid10160043, Akos025401976, Ac-27741, Ac-28948

Molecular Formula

C₄₉H₅₅N₉O₇

Molecular Weight

882.0 g/mol

InChI Key

UXXFHLOGQYUBLD-JFOPJMDSSA-N

1 2D Structure

Elbasvir

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

methyl N-[(2S)-1-[(2S)-2-[4-[(6S)-3-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-4H-imidazol-4-yl]-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazin-10-yl]-2H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate

2.1.2 InChI

InChI=1S/C49H55N9O7/c1-27(2)41(54-48(61)63-5)45(59)56-20-10-14-37(56)43-50-25-34(52-43)30-17-19-36-32(22-30)23-39-33-18-16-31(24-40(33)65-47(58(36)39)29-12-8-7-9-13-29)35-26-51-44(53-35)38-15-11-21-57(38)46(60)42(28(3)4)55-49(62)64-6/h7-9,12-13,16-19,22-28,35,37-38,41-43,47H,10-11,14-15,20-21H2,1-6H3,(H,54,61)(H,55,62)/t35?,37-,38-,41-,42-,43?,47-/m0/s1

2.1.3 InChI Key

UXXFHLOGQYUBLD-JFOPJMDSSA-N

2.1.4 Canonical SMILES

CC(C)C(C(=O)N1CCCC1C2N=CC(=N2)C3=CC4=C(C=C3)N5C(OC6=C(C5=C4)C=CC(=C6)C7C=NC(=N7)C8CCCN8C(=O)C(C(C)C)NC(=O)OC)C9=CC=CC=C9)NC(=O)OC

2.1.5 Isomeric SMILES

CC(C)[C@@H](C(=O)N1CCC[C@H]1C2N=CC(=N2)C3=CC4=C(C=C3)N5[C@@H](OC6=C(C5=C4)C=CC(=C6)C7C=NC(=N7)[C@@H]8CCCN8C(=O)[C@H](C(C)C)NC(=O)OC)C9=CC=CC=C9)NC(=O)OC

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. Dtxsid10160043

2. Akos025401976

3. Ac-27741

4. Ac-28948

2.3 Create Date

2013-09-21

3 Chemical and Physical Properties

Molecular Formula	C₄₉H₅₅N₉O₇
Molecular Weight	882.0 g/mol
XLogP3	5.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	13
Exact Mass	881.42244513 g/mol
Monoisotopic Mass	881.42244513 g/mol
Topological Polar Surface Area	181 Å²
Heavy Atom Count	65
Formal Charge	0
Complexity	1900
Isotope Atom Count	0
Defined Atom Stereocenter Count	5
Undefined Atom Stereocenter Count	2
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

Find Elbasvir manufacturers, exporters & distributors on PharmaCompass

Elbasvir

Elbasvir

Synopsis

Chemistry

APIs // Active Pharmaceutical Ingredients

4 API Suppliers

1 KDMF

1 NDC API

4 Listed Suppliers

INTERMEDIATES

8 Suppliers

DOSSIERs // Finished Dosage Formulations

3 Dossiers

1 FDA Orange Book

1 Europe

1 Listed Dossiers

RELATED EXCIPIENT COMPANIES

Suppliers

19 Kerry

13 SPI Pharma

13 Roquette

12 Microlex e.U

10 Gangwal Healthcare

10 Sigachi Industries

9 BASF

5 DFE Pharma

5 Gangwal Chemicals

5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

3 Prachin Chemical

3 Vasa Pharmachem

2 Actylis

2 Ingredion Pharma Solutions

1 Shijiazhuang Huaxu Pharmaceutical

1 Boai NKY Pharmaceuticals Ltd

1 Pharmatrans-Sanaq

1 DKSH

1 Huzhou Sunflower Pharmaceutical Co. Ltd

1 Bioplus Life Sciences

1 Seqens

1 Ideal Cures Pvt Ltd

1 PMC Isochem

1 Jai Radhe Sales

1 Pfanstiehl

1 Alcedo Pharmachem

1 Nanjing Well Pharmaceutical

1 Rochem International Inc

EXCIPIENTS BY APPLICATIONS

61 Fillers, Diluents & Binders

29 Direct Compression

17 Granulation

15 Disintegrants & Superdisintegrants

14 Taste Masking

13 Co-Processed Excipients

12 Thickeners and Stabilizers

12 Lubricants & Glidants

11 Chewable & Orodispersible Aids

8 Coating Systems & Additives

8 Film Formers & Plasticizers

6 Parenteral

6 Controlled & Modified Release

4 Emulsifying Agents

3 Solubilizers

2 API Stability Enhancers

2 Topical

2 Rheology Modifiers

1 Surfactant & Foaming Agents

GLOBAL SALES INFORMATION

1 Finished Drug Prices

MARKET PLACE

3 APIs

PATENTS

2 US Patents

1 US Exclusivities

DIGITAL CONTENT

2 Data Compilations & Company Tracker #PharmaFlow

32 News

API SUPPLIERS

API REF. PRICE (USD / KG)