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Chemistry

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Also known as: 910462-43-0, 4sc-202, (e)-n-(2-aminophenyl)-3-(1-((4-(1-methyl-1h-pyrazol-4-yl)phenyl)sulfonyl)-1h-pyrrol-3-yl)acrylamide, 264arm7uxx, Hdac inhibitor 4sc-202, 2-propenamide, n-(2-aminophenyl)-3-(1-((4-(1-methyl-1h-pyrazol-4-yl)phenyl)sulfonyl)-1h-pyrrol-3-yl)-, (2e)-
Molecular Formula
C23H21N5O3S
Molecular Weight
447.5  g/mol
InChI Key
PRXXYMVLYKJITB-IZZDOVSWSA-N
FDA UNII
264ARM7UXX

Domatinostat
inhibitor of human class I histone deacetylases
1 2D Structure

Domatinostat

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(E)-N-(2-aminophenyl)-3-[1-[4-(1-methylpyrazol-4-yl)phenyl]sulfonylpyrrol-3-yl]prop-2-enamide
2.1.2 InChI
InChI=1S/C23H21N5O3S/c1-27-16-19(14-25-27)18-7-9-20(10-8-18)32(30,31)28-13-12-17(15-28)6-11-23(29)26-22-5-3-2-4-21(22)24/h2-16H,24H2,1H3,(H,26,29)/b11-6+
2.1.3 InChI Key
PRXXYMVLYKJITB-IZZDOVSWSA-N
2.2 Other Identifiers
2.2.1 UNII
264ARM7UXX
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4sc-202

2.3.2 Depositor-Supplied Synonyms

1. 910462-43-0

2. 4sc-202

3. (e)-n-(2-aminophenyl)-3-(1-((4-(1-methyl-1h-pyrazol-4-yl)phenyl)sulfonyl)-1h-pyrrol-3-yl)acrylamide

4. 264arm7uxx

5. Hdac Inhibitor 4sc-202

6. 2-propenamide, N-(2-aminophenyl)-3-(1-((4-(1-methyl-1h-pyrazol-4-yl)phenyl)sulfonyl)-1h-pyrrol-3-yl)-, (2e)-

7. Domatinostatum

8. Refchem:920610

9. (2e)-n-(2-aminophenyl)-3-(1-(4-(1-methyl-1h-pyrazol-4-yl)benzenesulfonyl)-1h-pyrrol-3-yl)prop-2-enamide

10. 4sc-202 (free Base)

11. (e)-n-(2-aminophenyl)-3-[1-[4-(1-methylpyrazol-4-yl)phenyl]sulfonylpyrrol-3-yl]prop-2-enamide

12. Mfcd28155264

13. Unii-264arm7uxx

14. 4sc202

15. Domatinostat [inn]

16. Domatinostat (4sc-202)

17. Domatinostat [who-dd]

18. Orb1300834

19. Schembl1613939

20. Chembl4283683

21. Schembl30477018

22. Prxxymvlykjitb-izzdovswsa-n

23. Glxc-10802

24. Bcp18522

25. Bdbm50470579

26. Hy-16012a

27. S7555

28. Akos030526982

29. Ccg-269205

30. Cs-3275

31. Db13101

32. Ncgc00384199-04

33. 4sc-202?

34. As-77606

35. Bp-40062

36. Ns00072115

37. Brd-k11773281-001-01-2

38. Brd-k11773281-075-01-6

39. Brd-k11773281-075-02-4

40. Q27254045

41. (e)-n-(2-amino-phenyl)-3-{1-[4-(1-methyl-1h-pyrazol-4-yl)-benzene Sulfonyl]-1h-pyrrol-3-yl}-acrylamide

42. (e)-n-(2-amino-phenyl)-3-{1-[4-(1-methyl-1h-pyrazol-4-yl)-benzenesulfonyl]-1h-pyrrol-3-yl}-acrylamide

2.4 Create Date
2007-03-27
3 Chemical and Physical Properties
Molecular Weight 447.5 g/mol
Molecular Formula C23H21N5O3S
XLogP32.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area120
Heavy Atom Count32
Formal Charge0
Complexity775
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 910462-43-0 / Domatinostat API manufacturers, exporters & distributors?

Domatinostat manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Domatinostat API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Domatinostat manufacturer or Domatinostat supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Domatinostat manufacturer or Domatinostat supplier.

API | Excipient name

Domatinostat

Synonyms

910462-43-0, 4sc-202, (e)-n-(2-aminophenyl)-3-(1-((4-(1-methyl-1h-pyrazol-4-yl)phenyl)sulfonyl)-1h-pyrrol-3-yl)acrylamide, 264arm7uxx, Hdac inhibitor 4sc-202, 2-propenamide, n-(2-aminophenyl)-3-(1-((4-(1-methyl-1h-pyrazol-4-yl)phenyl)sulfonyl)-1h-pyrrol-3-yl)-, (2e)-

Cas Number

910462-43-0

Unique Ingredient Identifier (UNII)

264ARM7UXX

About Domatinostat

inhibitor of human class I histone deacetylases

Domatinostat Manufacturers

A Domatinostat manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Domatinostat, including repackagers and relabelers. The FDA regulates Domatinostat manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Domatinostat API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Domatinostat Suppliers

A Domatinostat supplier is an individual or a company that provides Domatinostat active pharmaceutical ingredient (API) or Domatinostat finished formulations upon request. The Domatinostat suppliers may include Domatinostat API manufacturers, exporters, distributors and traders.

Domatinostat GMP

Domatinostat Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Domatinostat GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Domatinostat GMP manufacturer or Domatinostat GMP API supplier for your needs.

Domatinostat CoA

A Domatinostat CoA (Certificate of Analysis) is a formal document that attests to Domatinostat's compliance with Domatinostat specifications and serves as a tool for batch-level quality control.

Domatinostat CoA mostly includes findings from lab analyses of a specific batch. For each Domatinostat CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Domatinostat may be tested according to a variety of international standards, such as European Pharmacopoeia (Domatinostat EP), Domatinostat JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Domatinostat USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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