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    Also known as: Dicloxacillin sodium, 13412-64-1, Dicloxacillin sodium salt monohydrate, Dicloxacillin sodium hydrate, Dynapen, Pathocil
    Molecular Formula
    C19H18Cl2N3NaO6S
    Molecular Weight
    510.3  g/mol
    InChI Key
    SIGZQNJITOWQEF-VICXVTCVSA-M
    FDA UNII
    4HZT2V9KX0
    Sodium Dicloxacillin
    One of the PENICILLINS which is resistant to PENICILLINASE.
    1 2D Structure

    Sodium Dicloxacillin

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;(2S,5R,6R)-6-[[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;hydrate
    2.1.2 InChI
    InChI=1S/C19H17Cl2N3O5S.Na.H2O/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1
    2.1.3 InChI Key
    SIGZQNJITOWQEF-VICXVTCVSA-M
    2.1.4 Canonical SMILES
    CC1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].O.[Na+]
    2.1.5 Isomeric SMILES
    CC1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)[O-].O.[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    4HZT2V9KX0
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Cilpen

    2. Dichloroxacillin

    3. Diclocil

    4. Dicloxaciclin

    5. Dicloxacillin

    6. Dicloxacillin Sodium

    7. Dicloxacillin, Monosodium Salt, Anhydrous

    8. Dicloxacillin, Monosodium Salt, Mono-hydrate

    9. Dicloxacycline

    10. Dicloxsig

    11. Distaph

    12. Ditterolina

    13. Dycill

    14. Dynapen

    15. Infectostaph

    16. Pathocil

    17. Posipen

    18. Sodium, Dicloxacillin

    2.3.2 Depositor-Supplied Synonyms

    1. Dicloxacillin Sodium

    2. 13412-64-1

    3. Dicloxacillin Sodium Salt Monohydrate

    4. Dicloxacillin Sodium Hydrate

    5. Dynapen

    6. Pathocil

    7. Dycill

    8. Dicloxacillin Sodium Salt Hydrate

    9. Diclocil

    10. Sodium Dicloxacillin Monohydrate

    11. Dicloxacillin (sodium Hydrate)

    12. Chebi:52019

    13. P-1011

    14. 4hzt2v9kx0

    15. Brispen

    16. Nsc-756726

    17. Monosodium (2s,5r,6r)-6-(3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate Monohydrate

    18. Digloxilline

    19. Biocloxin

    20. Constaphyl

    21. Novapen

    22. Noxaben

    23. Stampen

    24. Ciclex

    25. Clocil

    26. Diflor

    27. P 1011

    28. Pen-sint

    29. Dsstox_cid_28928

    30. Dsstox_rid_83194

    31. Dsstox_gsid_49002

    32. Staphcillin A Banyu

    33. Sodium Dicloxacillin Hydrate

    34. Dichlorstapenor Sodium

    35. Mdi-pc

    36. Bayer 5488

    37. Blp-1011

    38. Smr000875239

    39. Sodium (2s,5r,6r)-6-(3-(2,6-dichlorophenyl)-5-methylisoxazole-4-carboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Hydrate

    40. R 13423

    41. Ncgc00178782-02

    42. 343-55-5

    43. Sodium;(2s,5r,6r)-6-[[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;hydrate

    44. Unii-4hzt2v9kx0

    45. Dycill (tn)

    46. Mfcd00056865

    47. Dicloxacillinum Natricum

    48. Dicloxacillin Sodium [usan:usp:ban:jan]

    49. 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl Penicillin Sodium Monohydrate

    50. Dicloxacillin Sodium (usp)

    51. Cas-13412-64-1

    52. Schembl41515

    53. Mls001332403

    54. Mls001332404

    55. Mls002153818

    56. Chembl1200701

    57. Dtxsid2049002

    58. Hms2096i22

    59. Hms2234c13

    60. Hms3713i22

    61. Dicloxacillin Sodium [usan]

    62. Bcp28581

    63. Hy-b0977

    64. Dicloxacillin Sodium [vandf]

    65. Tox21_113495

    66. Bdbm50005106

    67. Dicloxacillin Sodium [mart.]

    68. Dicloxacillin Sodium Hydrate (jp17)

    69. S4111

    70. Dicloxacillin Sodium [usp-rs]

    71. Dicloxacillin Sodium [who-ip]

    72. Akos015962897

    73. Tox21_113495_1

    74. Ccg-220450

    75. Ccg-269777

    76. Cs-4467

    77. Nsc 756726

    78. Ncgc00178782-04

    79. Ncgc00180956-01

    80. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-(((3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, Monosodium Salt, Monohydrate, (2s,5r,6r)-

    81. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-(((3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, Monosodium Salt, Monohydrate, (2s-(2alpha,5alpha,6beta))-

    82. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-(3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-, Monosodium Salt, Monohydrate

    83. Ac-18976

    84. Dicloxacillin Sodium [orange Book]

    85. Dicloxacillin Sodium Hydrate [jan]

    86. Dicloxacillin Sodium [ep Monograph]

    87. Dicloxacillin Sodium [usp Impurity]

    88. Dicloxacillin Sodium [usp Monograph]

    89. D02137

    90. D81863

    91. Dicloxacillinum Natricum [who-ip Latin]

    92. Dicloxacillin Sodium Monohydrate [who-dd]

    93. Dicloxacillin Sodium Salt Monohydrate [mi]

    94. Dicloxacillin Sodium Monohydrate [green Book]

    95. Q27887689

    96. Dicloxacillin Sodium, European Pharmacopoeia (ep) Reference Standard

    97. Dicloxacillin Sodium Salt Hydrate, Vetranal(tm), Analytical Standard

    98. Dicloxacillin Sodium, United States Pharmacopeia (usp) Reference Standard

    99. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-(((3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, Monosodium Salt, Monohydrate, (2s-(2.alpha.,5.alpha.,6.beta.))-

    100. Sodium (2s,5r,6r)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Hydrate

    101. Sodium 6beta-{[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carboxamido}-2,2-dimethylpenam-3alpha-carboxylate--water (1/1)

    2.4 Create Date
    2008-02-05
    3 Chemical and Physical Properties
    Molecular Weight 510.3 g/mol
    Molecular Formula C19H18Cl2N3NaO6S
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count4
    Exact Mass509.0191061 g/mol
    Monoisotopic Mass509.0191061 g/mol
    Topological Polar Surface Area142 Ų
    Heavy Atom Count32
    Formal Charge0
    Complexity752
    Isotope Atom Count0
    Defined Atom Stereocenter Count3
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameDicloxacillin sodium
    Drug LabelDicloxacillin sodium is a semisynthetic antibiotic substance which resists destruction by the enzyme penicillinase(beta - lactamase). It is monosodium (2S,5R,6R)-6-[3-(2,6-dichlorophenyl)- 5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-4-thia-1-...
    Active IngredientDicloxacillin sodium
    Dosage FormCapsule
    RouteOral
    Strengtheq 500mg base; eq 125mg base; eq 250mg base
    Market StatusPrescription
    CompanyTeva; Sandoz

    2 of 2  
    Drug NameDicloxacillin sodium
    Drug LabelDicloxacillin sodium is a semisynthetic antibiotic substance which resists destruction by the enzyme penicillinase(beta - lactamase). It is monosodium (2S,5R,6R)-6-[3-(2,6-dichlorophenyl)- 5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-4-thia-1-...
    Active IngredientDicloxacillin sodium
    Dosage FormCapsule
    RouteOral
    Strengtheq 500mg base; eq 125mg base; eq 250mg base
    Market StatusPrescription
    CompanyTeva; Sandoz

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Penicillins [CS]; Penicillin-class Antibacterial [EPC]

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    08-Feb-2022
    11-Apr-2025
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    ABOUT THIS PAGE

    Looking for 13412-64-1 / Sodium Dicloxacillin API manufacturers, exporters & distributors?

    Sodium Dicloxacillin manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Sodium Dicloxacillin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Sodium Dicloxacillin manufacturer or Sodium Dicloxacillin supplier for your needs.

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    PharmaCompass also assists you with knowing the Sodium Dicloxacillin API Price utilized in the formulation of products. Sodium Dicloxacillin API Price is not always fixed or binding as the Sodium Dicloxacillin Price is obtained through a variety of data sources. The Sodium Dicloxacillin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Sodium Dicloxacillin

    Synonyms

    Dicloxacillin sodium, 13412-64-1, Dicloxacillin sodium salt monohydrate, Dicloxacillin sodium hydrate, Dynapen, Pathocil

    Cas Number

    13412-64-1

    Unique Ingredient Identifier (UNII)

    4HZT2V9KX0

    About Sodium Dicloxacillin

    One of the PENICILLINS which is resistant to PENICILLINASE.

    Dicloxacillin Sodium Manufacturers

    A Dicloxacillin Sodium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Dicloxacillin Sodium, including repackagers and relabelers. The FDA regulates Dicloxacillin Sodium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Dicloxacillin Sodium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Dicloxacillin Sodium manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Dicloxacillin Sodium Suppliers

    A Dicloxacillin Sodium supplier is an individual or a company that provides Dicloxacillin Sodium active pharmaceutical ingredient (API) or Dicloxacillin Sodium finished formulations upon request. The Dicloxacillin Sodium suppliers may include Dicloxacillin Sodium API manufacturers, exporters, distributors and traders.

    click here to find a list of Dicloxacillin Sodium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Dicloxacillin Sodium USDMF

    A Dicloxacillin Sodium DMF (Drug Master File) is a document detailing the whole manufacturing process of Dicloxacillin Sodium active pharmaceutical ingredient (API) in detail. Different forms of Dicloxacillin Sodium DMFs exist exist since differing nations have different regulations, such as Dicloxacillin Sodium USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Dicloxacillin Sodium DMF submitted to regulatory agencies in the US is known as a USDMF. Dicloxacillin Sodium USDMF includes data on Dicloxacillin Sodium's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Dicloxacillin Sodium USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Dicloxacillin Sodium suppliers with USDMF on PharmaCompass.

    Dicloxacillin Sodium CEP

    A Dicloxacillin Sodium CEP of the European Pharmacopoeia monograph is often referred to as a Dicloxacillin Sodium Certificate of Suitability (COS). The purpose of a Dicloxacillin Sodium CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Dicloxacillin Sodium EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Dicloxacillin Sodium to their clients by showing that a Dicloxacillin Sodium CEP has been issued for it. The manufacturer submits a Dicloxacillin Sodium CEP (COS) as part of the market authorization procedure, and it takes on the role of a Dicloxacillin Sodium CEP holder for the record. Additionally, the data presented in the Dicloxacillin Sodium CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Dicloxacillin Sodium DMF.

    A Dicloxacillin Sodium CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Dicloxacillin Sodium CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Dicloxacillin Sodium suppliers with CEP (COS) on PharmaCompass.

    Dicloxacillin Sodium WC

    A Dicloxacillin Sodium written confirmation (Dicloxacillin Sodium WC) is an official document issued by a regulatory agency to a Dicloxacillin Sodium manufacturer, verifying that the manufacturing facility of a Dicloxacillin Sodium active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Dicloxacillin Sodium APIs or Dicloxacillin Sodium finished pharmaceutical products to another nation, regulatory agencies frequently require a Dicloxacillin Sodium WC (written confirmation) as part of the regulatory process.

    click here to find a list of Dicloxacillin Sodium suppliers with Written Confirmation (WC) on PharmaCompass.

    Dicloxacillin Sodium NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Dicloxacillin Sodium as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Dicloxacillin Sodium API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Dicloxacillin Sodium as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Dicloxacillin Sodium and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Dicloxacillin Sodium NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Dicloxacillin Sodium suppliers with NDC on PharmaCompass.

    Dicloxacillin Sodium GMP

    Dicloxacillin Sodium Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Dicloxacillin Sodium GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Dicloxacillin Sodium GMP manufacturer or Dicloxacillin Sodium GMP API supplier for your needs.

    Dicloxacillin Sodium CoA

    A Dicloxacillin Sodium CoA (Certificate of Analysis) is a formal document that attests to Dicloxacillin Sodium's compliance with Dicloxacillin Sodium specifications and serves as a tool for batch-level quality control.

    Dicloxacillin Sodium CoA mostly includes findings from lab analyses of a specific batch. For each Dicloxacillin Sodium CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Dicloxacillin Sodium may be tested according to a variety of international standards, such as European Pharmacopoeia (Dicloxacillin Sodium EP), Dicloxacillin Sodium JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Dicloxacillin Sodium USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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