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Chemistry

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Also known as: 169590-41-4, Deramaxx, 4-(3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1h-pyrazol-1-yl)benzenesulfonamide, Sc 46, Sc 046, Sc 59046
Molecular Formula
C17H14F3N3O3S
Molecular Weight
397.4  g/mol
InChI Key
WAZQAZKAZLXFMK-UHFFFAOYSA-N
FDA UNII
VX29JB5XWV

Deracoxib
Deracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. It is sold in tablets, which have added beefy flavour to increase palatability. Deramaxx received FDA approval in August 2002 for "the control of post operative pain and inflammation associated with orthopedic surgery in dogs.
1 2D Structure

Deracoxib

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)pyrazol-1-yl]benzenesulfonamide
2.1.2 InChI
InChI=1S/C17H14F3N3O3S/c1-26-16-7-2-10(8-13(16)18)15-9-14(17(19)20)22-23(15)11-3-5-12(6-4-11)27(21,24)25/h2-9,17H,1H3,(H2,21,24,25)
2.1.3 InChI Key
WAZQAZKAZLXFMK-UHFFFAOYSA-N
2.1.4 Canonical SMILES
COC1=C(C=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F)F
2.2 Other Identifiers
2.2.1 UNII
VX29JB5XWV
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-(3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1h-pyrazol-1-yl)benzenesulfonamide

2. Deramaxx

3. Nsc 758935

2.3.2 Depositor-Supplied Synonyms

1. 169590-41-4

2. Deramaxx

3. 4-(3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1h-pyrazol-1-yl)benzenesulfonamide

4. Sc 46

5. Sc 046

6. Sc 59046

7. Sc-59046

8. Deracoxib [usan]

9. 4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1h-pyrazol-1-yl]benzenesulfonamide

10. Vx29jb5xwv

11. Nsc-758935

12. 4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)pyrazol-1-yl]benzenesulfonamide

13. Chembl28636

14. Chebi:73032

15. Deracoxib (usan)

16. Ncgc00095312-01

17. Dsstox_cid_25975

18. Dsstox_rid_81266

19. Dsstox_gsid_45975

20. Deram

21. Cas-169590-41-4

22. Deracoxib [usan:inn]

23. Unii-vx29jb5xwv

24. Deracoxibum

25. Deracoxib-[d4]

26. Deracoxib [inn]

27. Deracoxib [mi]

28. Spectrum2_000521

29. Spectrum3_001677

30. Spectrum4_001227

31. Spectrum5_001644

32. Deracoxib [who-dd]

33. Schembl24645

34. Bspbio_003493

35. Kbiogr_001694

36. Spbio_000501

37. Deracoxib [green Book]

38. Dtxsid4045975

39. Kbio3_002713

40. Ex-a887

41. Hms2093m12

42. Hms3886o18

43. Pharmakon1600-01505222

44. Zinc607803

45. Amy31402

46. Bcp04295

47. Tox21_111503

48. Bdbm50057583

49. Ccg-39562

50. Mfcd09837763

51. Nsc758935

52. S5711

53. Sc-046

54. Akos016009604

55. Tox21_111503_1

56. Bcp9000598

57. Db11395

58. Nsc 758935

59. 4-[5-(3-fluoro-4-methoxyphenyl)-3-(difluoromethyl)-1h-pyrazol-1-yl]benzenesulfonamide

60. Ncgc00095312-02

61. Ncgc00095312-04

62. 1-propanol, 2,2-dimethyl-, 1-benzoate

63. Ac-33031

64. As-19558

65. Hy-17509

66. Bcp0726000080

67. Sbi-0206729.p001

68. Ft-0665858

69. D03689

70. Ab01563051_01

71. Sr-05000001985

72. J-010565

73. Q5261287

74. Sr-05000001985-1

75. Brd-k68558722-001-02-4

76. 4-[3-difluoromethyl-5-(3-fluoro-4-methoxy-phenyl)-pyrazol-1-yl]-benzenesulfonamide

77. Benzenesulfonamide, 4-(3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1h-pyrazol-1-yl)-

2.4 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 397.4 g/mol
Molecular Formula C17H14F3N3O3S
XLogP32.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass397.07079698 g/mol
Monoisotopic Mass397.07079698 g/mol
Topological Polar Surface Area95.6 Ų
Heavy Atom Count27
Formal Charge0
Complexity596
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Cyclooxygenase Inhibitors

Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (See all compounds classified as Cyclooxygenase Inhibitors.)


API SUPPLIERS

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Fareva

Luxembourg

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

EPS
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Fareva

Luxembourg

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Excella GmbH

Germany

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

EPS
Not Confirmed
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Excella GmbH

Germany

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Fareva

Luxembourg

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

EPS
Not Confirmed
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Fareva

Luxembourg

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Alivira Animal Health

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

EPS
Not Confirmed
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Alivira Animal Health

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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NDC API

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DERACOXIB

NDC Package Code : 86055-0017

Start Marketing Date : 2019-11-23

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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EPS
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DERACOXIB

NDC Package Code : 46014-1170

Start Marketing Date : 2020-02-05

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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EPS
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DERACOXIB

NDC Package Code : 46014-1082

Start Marketing Date : 2012-08-03

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT FOR HUMAN P...

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Listed Suppliers

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Deracoxib

About the Company : Alivira Animal Health Limited has emerged as India's largest and 1st Global integrated animal health company specialising in manufacturing of Active Pharmaceutical Ingredients (API...

Alivira Animal Health Limited has emerged as India's largest and 1st Global integrated animal health company specialising in manufacturing of Active Pharmaceutical Ingredients (API) and Finished Dosage Formulations (FDF).Our logotype is inspired by nature and its different forms and shapes. From a microscopic view to the skin texture, footprint of a chosen animal. The circular shape evokes the idea of protection and control. It’s a closed and perfect shape that is naturally balanced, reminiscing the brand idea “Animals source of health.
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Fareva

Luxembourg
EPS
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Fareva

Luxembourg
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Deracoxib

About the Company : Fareva’s API division has special technologies for high potent APIs (HPAPIs) down to the OEB-6 level, aseptic crystallization (sterile APIs), Spray Drying etc, with volumes rangi...

Fareva’s API division has special technologies for high potent APIs (HPAPIs) down to the OEB-6 level, aseptic crystallization (sterile APIs), Spray Drying etc, with volumes ranging from a few kgs to multi tons production. Fareva’s Drug Product division offers different technologies: injectables (lyophilized, solution, suspension, vial, ampoules, pre-filled syringes), unidoses and multidoses BFS, solids (tablets, hard capsules, powders), semi-solids (cream, gel suppositories) and liquids (oral and external, sprays, aerosols).
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Canada

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DERACOXIB

Brand Name : DERAMAXX FLAVOR TABS

Dosage Form : TABLET

Dosage Strength : 25MG

Packaging : 7/30/90

Approval Date :

Application Number : 2265761

Regulatory Info :

Registration Country : Canada

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DERACOXIB

Brand Name : DERAMAXX FLAVOR TABS

Dosage Form : TABLET

Dosage Strength : 100MG

Packaging : 7/30/90

Approval Date :

Application Number : 2265788

Regulatory Info :

Registration Country : Canada

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EPS
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DERACOXIB

Brand Name : DERAMAXX FLAVOR TABS

Dosage Form : TABLET

Dosage Strength : 75MG

Packaging : 7/30/90

Approval Date :

Application Number : 2328720

Regulatory Info :

Registration Country : Canada

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ABOUT THIS PAGE

Looking for 169590-41-4 / Deracoxib API manufacturers, exporters & distributors?

Deracoxib manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Deracoxib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Deracoxib manufacturer or Deracoxib supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Deracoxib manufacturer or Deracoxib supplier.

PharmaCompass also assists you with knowing the Deracoxib API Price utilized in the formulation of products. Deracoxib API Price is not always fixed or binding as the Deracoxib Price is obtained through a variety of data sources. The Deracoxib Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Deracoxib

Synonyms

169590-41-4, Deramaxx, 4-(3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1h-pyrazol-1-yl)benzenesulfonamide, Sc 46, Sc 046, Sc 59046

Cas Number

169590-41-4

Unique Ingredient Identifier (UNII)

VX29JB5XWV

About Deracoxib

Deracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. It is sold in tablets, which have added beefy flavour to increase palatability. Deramaxx received FDA approval in August 2002 for "the control of post operative pain and inflammation associated with orthopedic surgery in dogs.

Deracoxib Manufacturers

A Deracoxib manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Deracoxib, including repackagers and relabelers. The FDA regulates Deracoxib manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Deracoxib API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Deracoxib manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Deracoxib Suppliers

A Deracoxib supplier is an individual or a company that provides Deracoxib active pharmaceutical ingredient (API) or Deracoxib finished formulations upon request. The Deracoxib suppliers may include Deracoxib API manufacturers, exporters, distributors and traders.

click here to find a list of Deracoxib suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Deracoxib NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Deracoxib as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Deracoxib API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Deracoxib as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Deracoxib and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Deracoxib NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Deracoxib suppliers with NDC on PharmaCompass.

Deracoxib GMP

Deracoxib Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Deracoxib GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Deracoxib GMP manufacturer or Deracoxib GMP API supplier for your needs.

Deracoxib CoA

A Deracoxib CoA (Certificate of Analysis) is a formal document that attests to Deracoxib's compliance with Deracoxib specifications and serves as a tool for batch-level quality control.

Deracoxib CoA mostly includes findings from lab analyses of a specific batch. For each Deracoxib CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Deracoxib may be tested according to a variety of international standards, such as European Pharmacopoeia (Deracoxib EP), Deracoxib JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Deracoxib USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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