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Chemistry

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Also known as: 1219707-39-7, Lcb01-0371, Lcb-01-0371, Lcb-010371, 43ep6xv33e, (5r)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one
Molecular Formula
C14H17FN4O3
Molecular Weight
308.31  g/mol
InChI Key
QLUWQAFDTNAYPN-LLVKDONJSA-N
FDA UNII
43EP6XV33E

Delpazolid
Lcb01 0371 is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).
1 2D Structure

Delpazolid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(5R)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one
2.1.2 InChI
InChI=1S/C14H17FN4O3/c1-17-4-5-18(9-16-17)13-3-2-10(6-12(13)15)19-7-11(8-20)22-14(19)21/h2-3,6,9,11,20H,4-5,7-8H2,1H3/t11-/m1/s1
2.1.3 InChI Key
QLUWQAFDTNAYPN-LLVKDONJSA-N
2.1.4 Canonical SMILES
CN1CCN(C=N1)C2=C(C=C(C=C2)N3CC(OC3=O)CO)F
2.1.5 Isomeric SMILES
CN1CCN(C=N1)C2=C(C=C(C=C2)N3C[C@@H](OC3=O)CO)F
2.2 Other Identifiers
2.2.1 UNII
43EP6XV33E
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Lcb01-0371

2.3.2 Depositor-Supplied Synonyms

1. 1219707-39-7

2. Lcb01-0371

3. Lcb-01-0371

4. Lcb-010371

5. 43ep6xv33e

6. (5r)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one

7. (5r)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1h)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one

8. (5r)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one

9. (r)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1h)-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one

10. 2-oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1h)-yl)-3-fluorophenyl)-5-(hydroxymethyl)-, (5r)-

11. Unii-43ep6xv33e

12. (5r)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1h)-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one

13. (5r)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)oxazolidin-2-one

14. Delpazolid [inn]

15. Delpazolid [who-dd]

16. Delpazolid (lcb01-0371)

17. Chembl1673408

18. Schembl11969210

19. Gtpl10999

20. Bcp25650

21. Ex-a1715

22. Db13077

23. Lcb-01,0371

24. Ac-33876

25. Hy-100180

26. Cs-0018175

27. Q27258646

2.4 Create Date
2009-09-28
3 Chemical and Physical Properties
Molecular Weight 308.31 g/mol
Molecular Formula C14H17FN4O3
XLogP30.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass308.12846858 g/mol
Monoisotopic Mass308.12846858 g/mol
Topological Polar Surface Area68.6 Ų
Heavy Atom Count22
Formal Charge0
Complexity450
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


Protein Synthesis Inhibitors

Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins. (See all compounds classified as Protein Synthesis Inhibitors.)


ABOUT THIS PAGE

Looking for 1219707-39-7 / Delpazolid API manufacturers, exporters & distributors?

Delpazolid manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Delpazolid API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Delpazolid manufacturer or Delpazolid supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Delpazolid manufacturer or Delpazolid supplier.

PharmaCompass also assists you with knowing the Delpazolid API Price utilized in the formulation of products. Delpazolid API Price is not always fixed or binding as the Delpazolid Price is obtained through a variety of data sources. The Delpazolid Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Delpazolid

Synonyms

1219707-39-7, Lcb01-0371, Lcb-01-0371, Lcb-010371, 43ep6xv33e, (5r)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one

Cas Number

1219707-39-7

Unique Ingredient Identifier (UNII)

43EP6XV33E

About Delpazolid

Lcb01 0371 is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).

Delpazolid Manufacturers

A Delpazolid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Delpazolid, including repackagers and relabelers. The FDA regulates Delpazolid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Delpazolid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Delpazolid Suppliers

A Delpazolid supplier is an individual or a company that provides Delpazolid active pharmaceutical ingredient (API) or Delpazolid finished formulations upon request. The Delpazolid suppliers may include Delpazolid API manufacturers, exporters, distributors and traders.

Delpazolid GMP

Delpazolid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Delpazolid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Delpazolid GMP manufacturer or Delpazolid GMP API supplier for your needs.

Delpazolid CoA

A Delpazolid CoA (Certificate of Analysis) is a formal document that attests to Delpazolid's compliance with Delpazolid specifications and serves as a tool for batch-level quality control.

Delpazolid CoA mostly includes findings from lab analyses of a specific batch. For each Delpazolid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Delpazolid may be tested according to a variety of international standards, such as European Pharmacopoeia (Delpazolid EP), Delpazolid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Delpazolid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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