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    Chemistry

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    Also known as: 1140909-48-3, Cabozantinib malate, Cabozantinib (s)-malate, Cabometyx, Cabozantinib malate (xl184), Xl184
    Molecular Formula
    C32H30FN3O10
    Molecular Weight
    635.6  g/mol
    InChI Key
    HFCFMRYTXDINDK-WNQIDUERSA-N
    FDA UNII
    DR7ST46X58
    Cabozantinib
    Cabozantinib S-malate is the s-malate salt form of cabozantinib, an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Cabozantinib strongly binds to and inhibits several RTKs, which are often overexpressed in a variety of cancer cell types, including hepatocyte growth factor receptor (MET), RET (rearranged during transfection), vascular endothelial growth factor receptor types 1 (VEGFR-1), 2 (VEGFR-2), and 3 (VEGFR-3), mast/stem cell growth factor (KIT), FMS-like tyrosine kinase 3 (FLT-3), TIE-2 (TEK tyrosine kinase, endothelial), tropomyosin-related kinase B (TRKB) and AXL. This may result in an inhibition of both tumor growth and angiogenesis, and eventually lead to tumor regression.
    1 2D Structure

    Cabozantinib

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2S)-2-hydroxybutanedioic acid
    2.1.2 InChI
    InChI=1S/C28H24FN3O5.C4H6O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18;5-2(4(8)9)1-3(6)7/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34);2,5H,1H2,(H,6,7)(H,8,9)/t;2-/m.0/s1
    2.1.3 InChI Key
    HFCFMRYTXDINDK-WNQIDUERSA-N
    2.1.4 Canonical SMILES
    COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F.C(C(C(=O)O)O)C(=O)O
    2.1.5 Isomeric SMILES
    COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F.C([C@@H](C(=O)O)O)C(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    DR7ST46X58
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Bms 907351

    2. Bms-907351

    3. Bms907351

    4. Cabozantinib

    5. Cometriq

    6. Xl 184

    7. Xl-184

    8. Xl184 Cpd

    2.3.2 Depositor-Supplied Synonyms

    1. 1140909-48-3

    2. Cabozantinib Malate

    3. Cabozantinib (s)-malate

    4. Cabometyx

    5. Cabozantinib Malate (xl184)

    6. Xl184

    7. Cabozantinib (s-malate)

    8. Cometriq

    9. Cabozantinib S-malate [usan]

    10. Dr7st46x58

    11. Bms907351

    12. Chebi:72319

    13. N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-n-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (s)-2-hydroxysuccinate

    14. Cabometyx (tn)

    15. Cometriq (tn)

    16. Cabozantinib Malate (jan)

    17. 1-n-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2s)-2-hydroxybutanedioic Acid

    18. Cabozantinib S-malate (usan)

    19. Cabozantinib Malate [jan]

    20. Unii-dr7st46x58

    21. Butanedioic Acid, 2-hydroxy-, (2s)-, Compd. With N-(4-((6,7-dimethoxy-4-quinolinyl)oxy)phenyl)-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1)

    22. Butanedioic Acid, 2-hydroxy-, (2s)-, Compd. With N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1)

    23. Xl184 Malate

    24. Cabozantinib L-malate

    25. Bms907351 Malate

    26. Xl184(cabozantinib Malate)

    27. Mls006010951

    28. Chembl2103868

    29. Dtxsid60915949

    30. Ex-a2819

    31. Mfcd20923480

    32. S4001

    33. 1140909-48-3 (malate)

    34. Akos025401945

    35. Cabozantinib S-malate [who-dd]

    36. Ccg-270301

    37. Cs-0201

    38. (2s)-2-hydroxybutanedioic Acid Compd. With N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n'-(4-fluor

    39. (2s)-2-hydroxybutanedioic Acid Compd. With N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1)

    40. Ac-27471

    41. As-75255

    42. Hy-12044

    43. Smr004702755

    44. Cabozantinib S-malate [orange Book]

    45. Sw218093-2

    46. D10095

    47. Q27139901

    48. (2s)-2-hydroxybutanedioic Acid Compd. With N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide

    49. (2s)-2-hydroxybutanedioic Acid Compd. With N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1)

    50. (2s)-2-hydroxybutanedioic Acid; N'1-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-n1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

    51. 1,1-cyclopropanedicarboxamide, N'-(4-((6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n-(4- Fluorophenyl)- Mono((2s)-2-hydroxybutanedioate)

    52. Cyclopropane-1,1-dicarboxylic Acid [4-(6,7-dimethoxy-quinoline-4-yloxy)-phenyl]-amide(4-fluoro-phenyl)-amide, (s) Malate Salt

    53. N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide Mono((2s)-2-hydroxybutanedioate)

    54. N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-n-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (s)-2-hydroxysuccinate

    55. N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (2s)-2-hydroxybutanedioate

    2.4 Create Date
    2008-12-22
    3 Chemical and Physical Properties
    Molecular Weight 635.6 g/mol
    Molecular Formula C32H30FN3O10
    Hydrogen Bond Donor Count5
    Hydrogen Bond Acceptor Count12
    Rotatable Bond Count11
    Exact Mass635.19152232 g/mol
    Monoisotopic Mass635.19152232 g/mol
    Topological Polar Surface Area194 Ų
    Heavy Atom Count46
    Formal Charge0
    Complexity924
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Indication

    * Renal Cell Carcinoma (RCC):

    Cabometyx is indicated as monotherapy for the treatment of advanced renal cell carcinoma (RCC):

    - in treatment-nave adults with intermediate or poor risk,

    - in adults following prior vascular endothelial growth factor (VEGF)-targeted therapy.

    Cabometyx, in combination with nivolumab, is indicated for the first-line treatment of advanced renal cell carcinoma in adults.

    * Hepatocellular Carcinoma (HCC):

    Cabometyx is indicated as monotherapy for the treatment of hepatocellular carcinoma (HCC) in adults who have previously been treated with sorafenib.

    5 Pharmacology and Biochemistry
    5.1 ATC Code

    L01EX07

    API Reference Price

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    4-Chloro-6,7-dimethoxyquinoline

    CAS Number : 35654-56-9

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    1-((4-Fluoro phenyl) Carbamoyl) Cyclopropane Carbo...

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    4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline

    CAS Number : 190728-25-7

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    Cyclopropane-1,1-dicarboxylic acid methyl ester

    CAS Number : 113020-21-6

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    1,1-Cyclopropanedicarboxylic acid

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    4-CHLORO-6,7-DIMETHOXYQUINOLINE

    CAS Number : 35654-56-9

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    CYCLOPROPANE-1,1-DICARBOXYLIC ACID

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    1-((4-FLUOROPHENYL)CARBAMOYL)CYCLOPROPANE-1- CARBO...

    CAS Number : 849217-48-7

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    4-((6,7-DIMETHOXY-QUINOLIN-4-YL)OXY)ANILINE

    CAS Number : 190728-25-7

    End Use API : Cabozantinib

    About The Company : Founded with a mission to transform strategic capital into specialty chemicals, Ami Group focuses on Agrochemicals, Cosmetics, and Polymers. Ami Organics Ltd. i...

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    4-chloro-6,7-dimethoxyquinoline

    CAS Number : 35654-56-9

    End Use API : Cabozantinib

    About The Company : We are into manufacturing of bulk drug Intermediates and Active Pharmaceutical Ingredients (API). Our core competence is contract manufacturing for our clients ...

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    DOSAGE - CAPSULE;ORAL - EQ 20MG BASE

    USFDA APPLICATION NUMBER - 203756

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    DOSAGE - CAPSULE;ORAL - EQ 80MG BASE

    USFDA APPLICATION NUMBER - 203756

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    01

    Brand Name : Cabometyx

    Cabozantinib

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    Cabozantinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2020 Revenue in Millions : 349

    2019 Revenue in Millions : 293

    Growth (%) : 19

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    Cabozantinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2021 Revenue in Millions : 390

    2020 Revenue in Millions : 349

    Growth (%) : 23

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    Cabozantinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2022 Revenue in Millions : 481

    2021 Revenue in Millions : 390

    Growth (%) : 23

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    Takeda

    Cabozantinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2022 Revenue in Millions : 59

    2021 Revenue in Millions : 54

    Growth (%) : 10

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    Cabozantinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2023 Revenue in Millions : 577

    2022 Revenue in Millions : 481

    Growth (%) : 19

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    Takeda

    Cabozantinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2023 Revenue in Millions : 56

    2022 Revenue in Millions : 60

    Growth (%) : 5

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    Cabozantinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2024 Revenue in Millions : 617

    2023 Revenue in Millions : 577

    Growth (%) : 7

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    Takeda

    Cabozantinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2024 Revenue in Millions : 58

    2023 Revenue in Millions : 56

    Growth (%) : 4

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    Cabozantinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2016 Revenue in Millions : 7

    2015 Revenue in Millions : Not Reported

    Growth (%) : New Launch

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    Cabozantinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2017 Revenue in Millions : 64

    2016 Revenue in Millions : 9

    Growth (%) : 618

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    Cabozantinib S-Malate (1 kg) API needed in India [ENA21473]
    A company that focuses on the research, development and manufacturing of OSDs, injectables, liquids & semi-solids is looking for suppliers of Cabozantinib S-Malate (1 kg) API for development purposes. The suppliers must support this enquiry with CoA.
    19 Dec 2024

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    19 Dec 2024

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    19 Dec 2024

    Belarus.png
    Various APIs needed in Belarus [ENA17152]
    A company that focuses on the manufacturing of tablets, capsules, liquids and injectables is looking for suppliers of Various APIs for both development & commercial purposes. The suppliers must support this enquiry with DMF & CoA. 1. Docetaxel (10 kg/ annum) API 2. Cabazitaxel (200 g/ annum) API 3. Oxaliplatin (30 kg/ annum) API 4. Gemcitabine (100 kg/ annum) API 5. Eribulin (200 g/ annum) API 6. Paclitaxel (40 kg/ annum) API 7. Carfilzomib (1 kg/ annum) API 8. Pemetrexed (5 kg/ annum) API 9. Irinotecan (20 kg/ annum) API 10. Carboplatin (90 kg/ annum) API 11. Axitinib (2 kg/ annum) API 12. Cabozantinib (11 kg/ annum) API 13. Vemurafenib (150 kg/ annum) API 14. Cobimetinib (3 kg/ annum) API 15. Tofacitinib (20 kg/ annum) API
    24 May 2023

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    24 May 2023

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    24 May 2023

    Latvia.png
    Cabozantinib API needed in Latvia [ENA16749]
    A leading company that focuses on manufacturing a wide range of FDFs including neurology, cardiology, infectology and allergology is looking for suppliers of Micronized Cabozantinib API. The required quantity is 1 kg for development & 10 kg - 50 kg for commercial purposes. The suppliers must support this enquiry with CoA.
    29 Mar 2023

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    29 Mar 2023

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    29 Mar 2023

    japan.png
    Various APIs needed in Japan [ENA13594]
    A pharmaceutical company that specializes in the manufacturing of pharmaceuticals products & functioning foods is looking for suppliers of Various APIs for development purpose. The required quantity is 80 kg - 100 kg/ annum. 1. JP Grade Dapagliflozin Propylene Glycolate Hydrate (Amorphous form) API 2. JP Grade Cabozantinib API
    10 May 2022

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    10 May 2022

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    10 May 2022

    korearepublicofnew.png
    Cabozantinib API needed in Korea [ENA13199]
    A company that specializes in R&D, manufacturing & marketing of various pharmaceutical products is looking for suppliers of Cabozantinib (S form) API for commercial purpose.
    04 Apr 2022

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    04 Apr 2022

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    04 Apr 2022

    Germany.png
    USP and Ph. Eur Grade Cabozantinib S-malate API needed in Germany [ENA07223]
    A nanotechnology-based drug development company focused on reformulations and reinventions of established drugs is looking for suppliers of USP and Ph. Eur Grade Cabozantinib S-malate API. The suppliers must support this enquiry with USDMF, GMP and EP/ASMF/EDMF. The final market is Europe & the US.
    05 May 2020

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    05 May 2020

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    05 May 2020

    Bangladesh.png
    Apalutamide, Cabozantinib malate and other APIs needed in Bangladesh [ENA02773]
    M.R Trading Corporation, Bangladesh is looking for suppliers of following APIs: 1. Apalutamide 2. Cabozantinib malate 3. Ruxolitinib Phosphate 4. Trabectedin INN 5. Venetoclax 6. Aflibercept Interested suppliers can contact Masud via Mob: +880 01725219963 or Email: info@mrtcbd.com.
    28 Nov 2018

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    28 Nov 2018

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    28 Nov 2018

    Market Place
    Enquiry// Various Active Pharmaceutical Ingredients needed in Bangladesh [ENA01104]
    Rainbow Pacific Ltd, a distribution company in Bangladesh is looking for suppliers of following APIs for their client: 1. Alectinib HCl INN (Micronized) 50 kg 2. Olaparib 14.5 kg 3. Apixaban 500 g 4. Cabozantinib Malate 4 kg 5. Neratinib Maleate 5 kg 6. Brigatinib 4.5 kg 7. Ponatinib HCl 2.5 kg Interested suppliers should contact Ms Mallika via Email: rainpac1@gmail.com or Tel: 88028033857.
    17 Jul 2018

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    17 Jul 2018

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    17 Jul 2018

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    Patents & EXCLUSIVITIES

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    ABOUT THIS PAGE

    Looking for 1140909-48-3 / Cabozantinib API manufacturers, exporters & distributors?

    Cabozantinib manufacturers, exporters & distributors 1

    82

    PharmaCompass offers a list of Cabozantinib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Cabozantinib manufacturer or Cabozantinib supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Cabozantinib manufacturer or Cabozantinib supplier.

    PharmaCompass also assists you with knowing the Cabozantinib API Price utilized in the formulation of products. Cabozantinib API Price is not always fixed or binding as the Cabozantinib Price is obtained through a variety of data sources. The Cabozantinib Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Cabozantinib

    Synonyms

    1140909-48-3, Cabozantinib malate, Cabozantinib (s)-malate, Cabometyx, Cabozantinib malate (xl184), Xl184

    Cas Number

    1140909-48-3

    Unique Ingredient Identifier (UNII)

    DR7ST46X58

    About Cabozantinib

    Cabozantinib S-malate is the s-malate salt form of cabozantinib, an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Cabozantinib strongly binds to and inhibits several RTKs, which are often overexpressed in a variety of cancer cell types, including hepatocyte growth factor receptor (MET), RET (rearranged during transfection), vascular endothelial growth factor receptor types 1 (VEGFR-1), 2 (VEGFR-2), and 3 (VEGFR-3), mast/stem cell growth factor (KIT), FMS-like tyrosine kinase 3 (FLT-3), TIE-2 (TEK tyrosine kinase, endothelial), tropomyosin-related kinase B (TRKB) and AXL. This may result in an inhibition of both tumor growth and angiogenesis, and eventually lead to tumor regression.

    Cometriq Manufacturers

    A Cometriq manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cometriq, including repackagers and relabelers. The FDA regulates Cometriq manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cometriq API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Cometriq manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Cometriq Suppliers

    A Cometriq supplier is an individual or a company that provides Cometriq active pharmaceutical ingredient (API) or Cometriq finished formulations upon request. The Cometriq suppliers may include Cometriq API manufacturers, exporters, distributors and traders.

    click here to find a list of Cometriq suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Cometriq USDMF

    A Cometriq DMF (Drug Master File) is a document detailing the whole manufacturing process of Cometriq active pharmaceutical ingredient (API) in detail. Different forms of Cometriq DMFs exist exist since differing nations have different regulations, such as Cometriq USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Cometriq DMF submitted to regulatory agencies in the US is known as a USDMF. Cometriq USDMF includes data on Cometriq's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Cometriq USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Cometriq suppliers with USDMF on PharmaCompass.

    Cometriq KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Cometriq Drug Master File in Korea (Cometriq KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Cometriq. The MFDS reviews the Cometriq KDMF as part of the drug registration process and uses the information provided in the Cometriq KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Cometriq KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Cometriq API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Cometriq suppliers with KDMF on PharmaCompass.

    Cometriq WC

    A Cometriq written confirmation (Cometriq WC) is an official document issued by a regulatory agency to a Cometriq manufacturer, verifying that the manufacturing facility of a Cometriq active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Cometriq APIs or Cometriq finished pharmaceutical products to another nation, regulatory agencies frequently require a Cometriq WC (written confirmation) as part of the regulatory process.

    click here to find a list of Cometriq suppliers with Written Confirmation (WC) on PharmaCompass.

    Cometriq NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Cometriq as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Cometriq API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Cometriq as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Cometriq and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Cometriq NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Cometriq suppliers with NDC on PharmaCompass.

    Cometriq GMP

    Cometriq Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Cometriq GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cometriq GMP manufacturer or Cometriq GMP API supplier for your needs.

    Cometriq CoA

    A Cometriq CoA (Certificate of Analysis) is a formal document that attests to Cometriq's compliance with Cometriq specifications and serves as a tool for batch-level quality control.

    Cometriq CoA mostly includes findings from lab analyses of a specific batch. For each Cometriq CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Cometriq may be tested according to a variety of international standards, such as European Pharmacopoeia (Cometriq EP), Cometriq JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cometriq USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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