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Chemistry

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Also known as: 1193314-23-6, Nitd609, Nitd 609, Nitd-609, Kae609, Cipargamin [inn]
Molecular Formula
C19H14Cl2FN3O
Molecular Weight
390.2  g/mol
InChI Key
CKLPLPZSUQEDRT-WPCRTTGESA-N
FDA UNII
Z7Q4FWA04P

Cipargamin
Cipargamin has been used in trials studying the treatment of Malaria, Cure Rate, and Plasmodium Falciparum Malaria.
1 2D Structure

Cipargamin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(3R,3'S)-5,7'-dichloro-6'-fluoro-3'-methylspiro[1H-indole-3,1'-2,3,4,9-tetrahydropyrido[3,4-b]indole]-2-one
2.1.2 InChI
InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1
2.1.3 InChI Key
CKLPLPZSUQEDRT-WPCRTTGESA-N
2.1.4 Canonical SMILES
CC1CC2=C(C3(N1)C4=C(C=CC(=C4)Cl)NC3=O)NC5=CC(=C(C=C25)F)Cl
2.1.5 Isomeric SMILES
C[C@H]1CC2=C([C@]3(N1)C4=C(C=CC(=C4)Cl)NC3=O)NC5=CC(=C(C=C25)F)Cl
2.2 Other Identifiers
2.2.1 UNII
Z7Q4FWA04P
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Kae609

2. Nitd 609

3. Nitd-609

4. Nitd609

2.3.2 Depositor-Supplied Synonyms

1. 1193314-23-6

2. Nitd609

3. Nitd 609

4. Nitd-609

5. Kae609

6. Cipargamin [inn]

7. 1252008-89-1

8. Spiro[3h-indole-3,1'-[1h]pyrido[3,4-b]indol]-2(1h)-one, 5,7'-dichloro-6'-fluoro-2',3',4',9'-tetrahydro-3'-methyl-, (1'r,3's)-

9. Z7q4fwa04p

10. (3r,3's)-5,7'-dichloro-6'-fluoro-3'-methylspiro[1h-indole-3,1'-2,3,4,9-tetrahydropyrido[3,4-b]indole]-2-one

11. Chembl1082723

12. Kae-609

13. (1'r,3's)-5,7'-dichloro-6'-fluoro-3'-methyl-2',3',4',9'-tetrahydrospiro[indoline-3,1'-pyrido[3,4-b]indol]-2-one

14. Rel-(1'r,3's)-5,7'-dichloro-6'-fluoro-3'-methyl-2',3',4',9'-tetrahydrospiro[indoline-3,1'-pyrido[3,4-b]indol]-2-one

15. Unii-z7q4fwa04p

16. Spiro(3h-indole-3,1'-(1h)pyrido(3,4-b)indol)-2(1h)-one, 5,7'-dichloro-6'-fluoro-2',3',4',9'-tetrahydro-3'-methyl-, (1'r,3's)-

17. Cipargamin [who-dd]

18. Gtpl9721

19. Schembl1306342

20. Dtxsid70152424

21. Bdbm50318666

22. Mfcd25976667

23. Zinc49037032

24. Cs-7486

25. Db12306

26. Nitd-609, (+)-

27. Ncgc00263785-01

28. As-51977

29. Hy-14430

30. P14044

31. Q6954404

32. (1'r,3's)-5,7'-dichloro-6'-fluoro-2',3',4',9'-tetrahydro-3'-methyl-spiro[3h-indole-3,1'-[1h]pyrido[3,4-b]indol]-2(1h)-one

33. (1'r,3's)-5,7'-dichloro-6'-fluoro-2',3',4',9'-tetrahydro-3'-methylspiro[3h-indole-3,1'-[1h]pyrido[3,4-b]indol]-2(1h)-one

34. (1r,3s)-5'',7-dichloro-6-fluoro-3-methyl-2,3,4,9-tetrahydrospiro-[beta-carboline-1,3''-indol]-2''(1''h)-one

35. (1r,3s)-5',7-dichloro-6-fluoro-3-methyl-spiro[2,3,4,9-tetrahydropyrido[3,4-b]indole-1,3'-indoline]-2'-one

36. (1r,3s)-5,7-dichloro-6-fluoro-3-methyl-2,3,4,9-tetrahydrospiro[indoline-3,1-pyrido[3,4-b]indol]-2-one

2.4 Create Date
2009-11-30
3 Chemical and Physical Properties
Molecular Weight 390.2 g/mol
Molecular Formula C19H14Cl2FN3O
XLogP33.9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass389.0497956 g/mol
Monoisotopic Mass389.0497956 g/mol
Topological Polar Surface Area56.9 Ų
Heavy Atom Count26
Formal Charge0
Complexity609
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 1193314-23-6 / Cipargamin API manufacturers, exporters & distributors?

Cipargamin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Cipargamin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Cipargamin manufacturer or Cipargamin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Cipargamin manufacturer or Cipargamin supplier.

PharmaCompass also assists you with knowing the Cipargamin API Price utilized in the formulation of products. Cipargamin API Price is not always fixed or binding as the Cipargamin Price is obtained through a variety of data sources. The Cipargamin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Cipargamin

Synonyms

1193314-23-6, Nitd609, Nitd 609, Nitd-609, Kae609, Cipargamin [inn]

Cas Number

1193314-23-6

Unique Ingredient Identifier (UNII)

Z7Q4FWA04P

About Cipargamin

Cipargamin has been used in trials studying the treatment of Malaria, Cure Rate, and Plasmodium Falciparum Malaria.

Cipargamin Manufacturers

A Cipargamin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cipargamin, including repackagers and relabelers. The FDA regulates Cipargamin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cipargamin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Cipargamin Suppliers

A Cipargamin supplier is an individual or a company that provides Cipargamin active pharmaceutical ingredient (API) or Cipargamin finished formulations upon request. The Cipargamin suppliers may include Cipargamin API manufacturers, exporters, distributors and traders.

Cipargamin GMP

Cipargamin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Cipargamin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cipargamin GMP manufacturer or Cipargamin GMP API supplier for your needs.

Cipargamin CoA

A Cipargamin CoA (Certificate of Analysis) is a formal document that attests to Cipargamin's compliance with Cipargamin specifications and serves as a tool for batch-level quality control.

Cipargamin CoA mostly includes findings from lab analyses of a specific batch. For each Cipargamin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Cipargamin may be tested according to a variety of international standards, such as European Pharmacopoeia (Cipargamin EP), Cipargamin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cipargamin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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