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Chemistry

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Also known as: 66592-87-8, Duricef, Cefadroxil hydrate, Bidocel, Cefadroxil 1-wasser, Duracef
Molecular Formula
C16H19N3O6S
Molecular Weight
381.4  g/mol
InChI Key
NBFNMSULHIODTC-CYJZLJNKSA-N
FDA UNII
280111G160

Cefadroxil Monohydrate
Long-acting, broad-spectrum, water-soluble, CEPHALEXIN derivative.
1 2D Structure

Cefadroxil Monohydrate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate
2.1.2 InChI
InChI=1S/C16H17N3O5S.H2O/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8;/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24);1H2/t10-,11-,15-;/m1./s1
2.1.3 InChI Key
NBFNMSULHIODTC-CYJZLJNKSA-N
2.1.4 Canonical SMILES
CC1=C(N2C(C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)SC1)C(=O)O.O
2.1.5 Isomeric SMILES
CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)SC1)C(=O)O.O
2.2 Other Identifiers
2.2.1 UNII
280111G160
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4 Hydroxycephalexin

2. 4-hydroxycephalexin

3. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, (6r-(6alpha,7beta(r*)))-

4. Bidocef

5. Bl S 578

6. Bl S578

7. Bl-s 578

8. Bl-s578

9. Bls 578

10. Bls578

11. Cefadroxil

12. Cefadroxil Anhydrous

13. Cephadroxyl

14. Duricef

15. S 578

16. S-578

17. S578

18. Ultracef

2.3.2 Depositor-Supplied Synonyms

1. 66592-87-8

2. Duricef

3. Cefadroxil Hydrate

4. Bidocel

5. Cefadroxil 1-wasser

6. Duracef

7. Mjf 11567-3

8. Bl-s578

9. Cefadroxil (hydrate)

10. (6r,7r)-7-((r)-2-amino-2-(p-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid Monohydrate

11. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2r)-amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, Monohydrate, (6r,7r)-

12. 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid,7-[[(2r)-amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-,monohydrate, (6r,7r)-

13. Ultracef

14. Moxacef Kapseln

15. Baxan Kapseln

16. Cefos Granulat

17. Kefroxil Kapseln

18. Omnidrox Kapseln

19. Mjf-11567-3

20. 280111g160

21. Cefadroxil (as Monohydrate)

22. (6r,7r)-7-((r)-2-amino-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Hydrate

23. (6r,7r)-7-[[(2r)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid;hydrate

24. Cefadroxil (usp)

25. Duricef (tn)

26. Unii-280111g160

27. Cefadroxil [usan:usp:inn:ban:jan]

28. (6r,7r)-7-[[(2r)-2-azaniumyl-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

29. Cefadroxil [usan]

30. Cefadroxil [vandf]

31. Cefadroxil [usp-rs]

32. Schembl33620

33. Cefadroxil [green Book]

34. Chebi:53667

35. Hy-b1190a

36. Dtxsid80904597

37. Cefadroxil [usp Monograph]

38. Cefadroxil Monohydrate [mi]

39. S3636

40. Cefadroxil Monohydrate [vandf]

41. Akos015896360

42. Ccg-268421

43. Cefadroxil Monohydrate [who-dd]

44. Nsc 756664

45. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, Monohydrate, (6r-(6alpha,7beta(r*)))-

46. As-75209

47. Cefadroxil Monohydrate [ep Monograph]

48. Cs-0014294

49. D02353

50. D95152

51. Q27124149

52. (6r,7r)-7-((r)-2-amino-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacidhydrate

53. (6r,7r)-7-[(2r)-2-amino-2-(4-hydroxyphenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Hydrate

54. (6r,7r)-7-{[(2r)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid--water (1/1)

55. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, Monohydrate, (6r-(6.alpha.,7.beta.(r*)))

56. 7beta-{[(2r)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,4-didehydrocepham-4-carboxylic Acid--water (1/1)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 381.4 g/mol
Molecular Formula C16H19N3O6S
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count8
Rotatable Bond Count4
Exact Mass381.09945651 g/mol
Monoisotopic Mass381.09945651 g/mol
Topological Polar Surface Area159 Ų
Heavy Atom Count26
Formal Charge0
Complexity629
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


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Looking for 66592-87-8 / Cefadroxil Monohydrate API manufacturers, exporters & distributors?

Cefadroxil Monohydrate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Cefadroxil Monohydrate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Cefadroxil Monohydrate manufacturer or Cefadroxil Monohydrate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Cefadroxil Monohydrate manufacturer or Cefadroxil Monohydrate supplier.

PharmaCompass also assists you with knowing the Cefadroxil Monohydrate API Price utilized in the formulation of products. Cefadroxil Monohydrate API Price is not always fixed or binding as the Cefadroxil Monohydrate Price is obtained through a variety of data sources. The Cefadroxil Monohydrate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Cefadroxil Monohydrate

Synonyms

66592-87-8, Duricef, Cefadroxil hydrate, Bidocel, Cefadroxil 1-wasser, Duracef

Cas Number

66592-87-8

Unique Ingredient Identifier (UNII)

280111G160

About Cefadroxil Monohydrate

Long-acting, broad-spectrum, water-soluble, CEPHALEXIN derivative.

Cefos Granulat Manufacturers

A Cefos Granulat manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cefos Granulat, including repackagers and relabelers. The FDA regulates Cefos Granulat manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cefos Granulat API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Cefos Granulat Suppliers

A Cefos Granulat supplier is an individual or a company that provides Cefos Granulat active pharmaceutical ingredient (API) or Cefos Granulat finished formulations upon request. The Cefos Granulat suppliers may include Cefos Granulat API manufacturers, exporters, distributors and traders.

Cefos Granulat GMP

Cefos Granulat Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Cefos Granulat GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cefos Granulat GMP manufacturer or Cefos Granulat GMP API supplier for your needs.

Cefos Granulat CoA

A Cefos Granulat CoA (Certificate of Analysis) is a formal document that attests to Cefos Granulat's compliance with Cefos Granulat specifications and serves as a tool for batch-level quality control.

Cefos Granulat CoA mostly includes findings from lab analyses of a specific batch. For each Cefos Granulat CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Cefos Granulat may be tested according to a variety of international standards, such as European Pharmacopoeia (Cefos Granulat EP), Cefos Granulat JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cefos Granulat USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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