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Find Drugs in Development News & Deals for Cannabidiolic Acid

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Details:

Cannabinoid oral solution has received approval for the treatment of several neurological disorders. It functions by stimulating two receptors, cannabinoid receptor type 1 and type 2, within the endocannabinoid system, maintaining body's homeostatis.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 15, 2023

Biophore CB

EMWA 2024

Not Confirmed

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Details:

Under the terms of the agreement, Vectura will undertake formulation screening studies, manufacturing process optimisation studies and stability assessments, as well as manufacturing a laboratory-scale batch of IHL-216A (Cannabidiol) to support toxicological studies.


Lead Product(s): Cannabidiol,Isoflurane

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: IHL-216A

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Incannex Healthcare

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement June 22, 2021

Skyepharma Company Banner

EMWA 2024

Not Confirmed

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Details:

Cannabis stimulates two receptors, cannabinoid receptor type 1 (CB1) and type 2 (CB2), within the endocannabinoid system. It is being investigated for multiple indications like post-surgical pain, depressive disorders, chronic headaches, alzheimer's agitation disorder, etc.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 01, 2023

Medipharm CB

EMWA 2024

Not Confirmed

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Details:

MediPharmto design, manufacture and supply a liquid oral cannabis study drug for the Phase 2 Life’s end Benefits of cannabidiol and tetrahydrocannabinol (LiBBY) study, to be conducted in the U.S., across 20 sites, to treat hospice-eligible patients diagnosed with dementia and agitation.


Lead Product(s): Cannabidiol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: T2:C100

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: National Institutes of Health

Deal Size: $16.0 million Upfront Cash: Undisclosed

Deal Type: Funding August 09, 2022

Medipharm CB

EMWA 2024

Not Confirmed

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Details:

New CBG products include Advanced Formula, which is a CBG:CBD 1:2 oil, and Northbound, which is a high CBG vape cartridge with CBD inspired by The White and Appalachia strains.


Lead Product(s): Cannabigerol,Cannabidiol

Therapeutic Area: Neurology Product Name: CBG:CBD

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 05, 2022

Medipharm CB

EMWA 2024

Not Confirmed

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Details:

Naturally derived oil and inhalable cannabigerol (cannabinoid) products added to MediPharm's wellness portfolio – the benefits of CBG without the effects of THC.


Lead Product(s): Cannabidiol,Cannabigerol

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 05, 2022

Medipharm CB

EMWA 2024

Not Confirmed

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Details:

McMaster University researchers using MediPharm Labs’ CBD50 formula and CBD:THC 10:2 formulation, which has the same as MediPharm Labs’ CBD25, have received a No Objection Letter from Health Canada to begin recruiting human subjects for a placebo-controlled trial.


Lead Product(s): Cannabidiol

Therapeutic Area: Sleep Product Name: CBD50

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: McMaster University

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 31, 2021

Medipharm CB

EMWA 2024

Not Confirmed

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Details:

Three initial proposed clinical trials will evaluate the effectiveness of proprietary THC and CBD (cannabidiol) drug candidates for multiple indications including Pain, Insomnia associated with Major Depression, and Uremic Pruritus.


Lead Product(s): Cannabidiol,Tetrahydrocannabinol

Therapeutic Area: Sleep Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: McMaster University

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement June 21, 2021

Medipharm CB

EMWA 2024

Not Confirmed

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Details:

Patients in Germany are now able to access GMP-certified quality medical cannabis from STADA through local pharmacies under the brand – CannabiSTADA, distributed through STADAPHARM, a direct subsidiary of STADA.


Lead Product(s): Tetrahydrocannabinol,Cannabidiol

Therapeutic Area: Neurology Product Name: CannabiSTADA

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: European Pharmaceutical

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement April 01, 2021

Medipharm CB

EMWA 2024

Not Confirmed

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Details:

As a result of agreement, patients in Germany are now able to access GMP-certified quality medical cannabis from STADA through local pharmacies under the brand – CannabiSTADA (cannabidiol), distributed through STADAPHARM, a direct subsidiary of STADA.


Lead Product(s): Cannabidiol,Tetrahydrocannabinol

Therapeutic Area: Gastroenterology Product Name: CannabiStada

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: STADA Arzneimittel

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement April 01, 2021

Medipharm CB

EMWA 2024

Not Confirmed

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Details:

LPT CBD (cannabinoid) is a loaded liposome platform facilitating exact dosing and the prolonged and controlled release of CBD into the blood stream. It is being evaluated for the treatment for chronic pain management.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: LPT-CBD

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 22, 2024

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The company will use the proceeds for developing its proprietary formulations and pharmaceutical pipeline including, RHO Phyto having diverse range of proprietary formulations including oral, sublingual, topical, and transdermal deliveries with varying ratios of cannabinoids.


Lead Product(s): Cannabidiol

Therapeutic Area: Musculoskeletal Product Name: RHO Phyto

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $2.1 million Upfront Cash: Undisclosed

Deal Type: Private Placement April 18, 2024

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RHO Phyto Micro Drop 100, a 10% CBD (THC free) is a proprietary oral formulation of cannabidiol, which is a CB1 receptor negative allosteric modulator. It is indicated for the treatment of seizures related to Lennox-Gastaut Syndrome and Dravet Syndrome.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: RHO Phyto

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 27, 2024

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The agreement facilitates Innocan to initiate the FDA approval process for its liposome CBD platform (LPT-CBD), facilitating prolonged and controlled release of CBD into the blood stream. It is being evaluated for the treatment of epilepsy and for pain management.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: LPT-CBD

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Hebrew University

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement March 25, 2024

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Under the agreement, GenBio will license potentially new, next generation of anti-inflammatory cannabinoids to be included in Strainsforpains CBD branded products.


Lead Product(s): Cannabidiol

Therapeutic Area: Immunology Product Name: Undisclosed

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: Strainsforpains

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement March 14, 2024

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The acquisition expands Branded Legacy's portfolio ranging from gummies to compression sleeves and pain-relieving topical creams, including Relief Gummy, which contains a balanced ratio of CBD to Nano Delta-9-THC.


Lead Product(s): Cannabidiol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: Relief Gummy

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Branded Legacy, Inc

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition March 12, 2024

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EmpowerCBD (cannabidiol oral solution) is a CB1 receptor negative allosteric modulator. It is being evaluated for the treatment of social anxiety disorder.


Lead Product(s): Cannabidiol

Therapeutic Area: Psychiatry/Psychology Product Name: EmpowerCBD

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 11, 2024

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SCI-210 a combination of cannabidiol (CBD) and CannAmide™ (SciSparc’s Palmitoylethanolamide), which is being evaluated for the treatment of Autism Spectrum Disorder in children between 5 and 18 years.


Lead Product(s): Cannabidiol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-210

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 08, 2024

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LPT-CBD (cannabidiol) is a CB1 receptor negative allosteric modulator, which is being evaluated for the treatment of patients suffering from neurological diseases.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: LPT-CBD

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 05, 2024

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DehydraTECH-CBD (cannabidiol) is a DehydraTECH-processed CB1 receptor negative allosteric modulator, which is being evaluated for the treatment of diabetes and weight loss.


Lead Product(s): Cannabidiol

Therapeutic Area: Nutrition and Weight Loss Product Name: DehydraTECH-CBD

Highest Development Status: DiscoveryProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 05, 2024

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SCI- 210 consisits of cannabidiol (CBD), a non-psychoactive cannabinoid, and PEA (palmitoylethanolamide). It is being developed for the treatment of Autism Spectrum Disorder.


Lead Product(s): Palmitoylethanolamide,Cannabidiol

Therapeutic Area: Neurology Product Name: SCI-210

Highest Development Status: Phase I/ Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 29, 2024

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  • Development Update

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ProZ-001 (cannabidiol) is a CB1 receptor negative allosteric modulator, which is approved for the treatment of patients with dravet syndrome and lennox-gastaut syndrome.


Lead Product(s): Cannabidiol

Therapeutic Area: Psychiatry/Psychology Product Name: ProZ-001

Highest Development Status: Phase II/ Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 27, 2024

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LPT CBD (cannabinoid) is a loaded liposome platform facilitating exact dosing and the prolonged and controlled release of CBD into the blood stream. It is being evaluated for the treatment of epilepsy and for pain management.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: LPT-CBD

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 26, 2024

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Lipid-CBD (cannabidiol) is a CB1 receptor negative allosteric modulator, which is being evaluated for the treatment of patients suffering from neurological diseases.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: Lipid-CBD

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 22, 2024

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Trunerox (cannabidiol) is a CB1 receptor negative allosteric modulator, which is approved for the treatment of patients with dravet syndrome and lennox-gastaut syndrome.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: Trunerox

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 20, 2024

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The exclusive supply agreement is for the Company’s proprietary topical products that have been commercialized in the Canadian market under the RHO Phyto brand, including AVCN-583601, Ultra-CBD cream, a CBD localized cream developed to target dermatology conditions.


Lead Product(s): Cannabidiol

Therapeutic Area: Rare Diseases and Disorders Product Name: AVCN-583601

Highest Development Status: Phase II/ Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement February 05, 2024

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SCI-210 (cannabidiol) is a combination of cannabidiol (CBD) and CannAmide™ (SciSparc’s Palmitoylethanolamide), which is being evaluated in clinical trials for the treatment of autism spectrum disorder.


Lead Product(s): Cannabidiol,Cannamide

Therapeutic Area: Neurology Product Name: SCI-210

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 29, 2024

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Under the agreement, Sipp Industries will manufacture SinuSave® CBD Nasal Spray products. SinuSave® CBD is proven to be bacteriostatic and bactericidal.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: SinuSave

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: SinuSave

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement January 23, 2024

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The company is aiming to concentrate on the clinical advancement of THC:CBD (Tetrahydrocannabinol), a partial agonist of the CB1 receptor with Cannabidiol. Both controlled substances will undergo evaluation for the treatment of chemotherapy-induced neuropathic pain.


Lead Product(s): Tetrahydrocannabinol,Cannabidiol

Therapeutic Area: Neurology Product Name: THC:CBD

Highest Development Status: UndisclosedProduct Type: Small molecule

Partner/Sponsor/Collaborator: German Pain Association

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration January 23, 2024

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Clasepi (cannabidiol) is an oral CB1 receptor negative allosteric modulator. It has been launched in India for the treatment of patients with Epilepsy.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: Clasepi

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 12, 2024

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Clasepi is a prescription cannabidiol (CBD) specifically formulated to address seizures linked with Lennox-Gastaut Syndrome (LGS), Dravet Syndrome, or Tuberous Sclerosis Complex (TSC) in patients aged 1 year and older. It is now approved for Epilepsy in India.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: Clasepi

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 10, 2024

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SAP021 (cannabidiol) is an oral CB1 receptor negative allosteric modulator. It is being evaluated in phase 1 clinical trials for the treatment of neurological diseases.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: SAP021

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 19, 2023

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SAP021 is an orally administered cannabinoid. It is under phase 1 clinical development for the treatment of neurological diseases.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: SAP021

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 19, 2023

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The company will use the proceeds for developing its proprietary formulations and pharmaceutical pipeline including, RHO Phyto having diverse range of proprietary formulations including oral, sublingual, topical, and transdermal deliveries with varying ratios of cannabinoids.


Lead Product(s): Cannabidiol,Cannabigerol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: RHO Phyto

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $0.8 million Upfront Cash: Undisclosed

Deal Type: Private Placement December 04, 2023

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Epidiolex (cannabidiol) is an oral CB receptor CB1 receptor negative allosteric modulator. It is now approved for the treatment of seizures associated with Lennox-Gastaut syndrome & Dravet syndrome in patients 2 years of age and older.


Lead Product(s): Cannabidiol

Therapeutic Area: Rare Diseases and Disorders Product Name: Epidiolex

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 23, 2023

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SAP021 (cannabidiol) is an oral CB1 receptor negative allosteric modulator. It is being evaluated in phase 1 clinical trials for the treatment of neurological diseases.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: SAP021

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 21, 2023

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Trichomylin softgels, a first-in-class drug product candidate formulated with a proprietary fixed-dose cannabinoid combination, has been specifically designed for the management of chronic pain.


Lead Product(s): Cannabidiol,Cannabichromene,Tetrahydrocannabinol

Therapeutic Area: Musculoskeletal Product Name: Trichomylin

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 21, 2023

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Cannabidiol is a CB1 receptor negative allosteric modulator (NAM), which is being evaluated in preclinical studies for the treatment of Pain.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 23, 2023

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The Company intends to use the net proceeds to fund the Company's pre-investigational new drug meeting regarding the human application of the Company's products, including Cannabidiol.


Lead Product(s): Cannabidiol

Therapeutic Area: Immunology Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Research Capital Corporation

Deal Size: $1.6 million Upfront Cash: Undisclosed

Deal Type: Private Placement October 20, 2023

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The Company intends to use the net proceeds from the Offering to fund the Company's pre-investigational new drug meeting with the United States FDA regarding the human application and expansion of the Company's derma-cosmetic product distribution.


Lead Product(s): Cannabidiol,Menthol,Camphor

Therapeutic Area: Neurology Product Name: Relief & Go

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Research Capital Corporation

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Private Placement October 12, 2023

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Through the acquisition, Harmony gets the opportunity to advance the development of a treatment for the symptoms of Fragile X syndrome and other rare neuropsychiatric disorders including, Zygel, the first and only pharmaceutically manufactured, synthetic cannabidiol.


Lead Product(s): Cannabidiol

Therapeutic Area: Genetic Disease Product Name: Zygel

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Harmony Biosciences

Deal Size: $200.0 million Upfront Cash: $200.0 million

Deal Type: Acquisition October 11, 2023

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SCI-210 is a proprietary combination of cannabidiol (CBD), a non-psychoactive cannabinoid, and PEA, clinical trial will investigate SCI-210 in comparison to CBD monotherapy in treating ASD.


Lead Product(s): Cannabidiol,Cannamide

Therapeutic Area: Neurology Product Name: SCI-210

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 29, 2023

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Endosane is focused on preclinical studies to evaluate the brain delivery characteristics of sol-gel technology and whether pharmacologically relevant concentrations of Cannabidiol can be achieved with this technology.


Lead Product(s): Cannabidiol

Therapeutic Area: Psychiatry/Psychology Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Endosane Pharmaceuticals

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 18, 2023

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  • Development Update

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Cannabidiol, a chemical compound from the cannabis plant, that help improvement in social and motor problems, a reduction in epilepsy and an increase in life expectancy in Leigh syndrome mouse models.


Lead Product(s): Cannabidiol

Therapeutic Area: Rare Diseases and Disorders Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 14, 2023

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Cannabidiol is a topical CB1 receptor negative allosteric modulator (NAM), which is being evaluated in phase 1 clinical studies for the treatment of Diabetic Foot.


Lead Product(s): Cannabidiol

Therapeutic Area: Podiatry Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 15, 2023

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Through the acquisition, Harmony gets the opportunity to advance the development of a treatment for the symptoms of Fragile X syndrome and other rare neuropsychiatric disorders including, Zygel, the first and only pharmaceutically manufactured, synthetic cannabidiol.


Lead Product(s): Cannabidiol

Therapeutic Area: Genetic Disease Product Name: Zygel

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Harmony Biosciences

Deal Size: $200.0 million Upfront Cash: $200.0 million

Deal Type: Acquisition August 14, 2023

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The agreement aims to perform a clinical pharmacology study of the uptake of cannabidiol (CBD) in a formulation which can be delivered as a pill orally.


Lead Product(s): Cannabidiol

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Hebrew University

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement August 07, 2023

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Details:

The company expects to use the net proceeds to advance its clinical development programs, including MIRA1a (synthetic tetrahydrocannabinol analog), being developed as the first prescription drug to target the CB1 and CB2 receptors for chronic pain and anxiety.


Lead Product(s): Tetrahydrocannabinol Analog,Cannabidiol

Therapeutic Area: Psychiatry/Psychology Product Name: MIRA1A

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: Kingswood Investments

Deal Size: $8.9 million Upfront Cash: Undisclosed

Deal Type: Public Offering August 07, 2023

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Details:

The company will use the proceeds for developing its proprietary formulations and pharmaceutical pipeline including, RHO Phyto having diverse range of proprietary formulations including oral, sublingual, topical, and transdermal deliveries with varying ratios of cannabinoids.


Lead Product(s): Cannabidiol,Cannabigerol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: RHO Phyto

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $1.4 million Upfront Cash: Undisclosed

Deal Type: Private Placement August 02, 2023

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Details:

The proceeds will be used for production, raw material and laboratory costs associated with production of GMP cannabinoid medicines CannEpil, a high-CBD, low-THC formulation delivered by an oral mucosal solution and CogniCann, an oral spray that combines THC and CBD.


Lead Product(s): Cannabidiol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: CannEpil

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Oberon Capital

Deal Size: $2.6 million Upfront Cash: Undisclosed

Deal Type: Financing August 01, 2023

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