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1. 5-(2-(tert-butylamino)-1-hydroxyethyl)-3-phenylene Bis(dimethylcarbamate)
2. Bambuterol Hydrochloride
1. 81732-65-2
2. Bambec
3. Bambuterolum
4. Bambuterol (inn)
5. Chebi:553827
6. [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,n-dimethylcarbamate
7. Y1850g1ovc
8. (+/-)-bambuterol;kwd-2183
9. (+-)-5-(2-(tert-butylamino)-1-hydroxyethyl)-m-phenylene Bis(dimethylcarbamate)
10. Bambuterolum [latin]
11. Oxeol
12. Bambuterol [inn]
13. Kwd-2183
14. 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diyl Bis(dimethylcarbamate)
15. (+/-)-5-(2-(tert-butylamino)-1-hydroxyethyl)-m-phenylene Bis(dimethylcarbamate)
16. Terbutaline Bisdimethylcarbamate
17. Bambuterol [inn:ban]
18. Unii-y1850g1ovc
19. Terbutaline Bis(dimethylcarbamate)
20. Bambuterol [mi]
21. Prestwick0_000361
22. Prestwick1_000361
23. Prestwick2_000361
24. Prestwick3_000361
25. Schembl4431
26. Bambuterol [who-dd]
27. Bspbio_000481
28. Mls002153785
29. Spbio_002402
30. Bpbio1_000531
31. Chembl521589
32. Gtpl6601
33. Dtxsid5048550
34. Glxc-25236
35. Hms2089j18
36. Hms2230o15
37. Hms3373n13
38. Bcp21793
39. Bdbm50235800
40. Stk643808
41. Akos005574764
42. Cs-3157
43. Db01408
44. ( Inverted Exclamation Marka)-bambutero
45. ( Inverted Exclamation Marka)-bambuterol
46. Ncgc00179546-01
47. Ncgc00179546-02
48. Ac-35438
49. Hy-17501
50. Smr001233168
51. Sbi-0207028.p001
52. Ft-0602901
53. D07377
54. 732b652
55. A840189
56. L004435
57. Q3633651
58. Sr-05000001470-1
59. Brd-a17462676-003-03-3
60. Brd-a17462676-003-06-6
61. (rs)-5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diyl Bis(dimethylcarbamate)
62. 5-(2-(tert-butylamino)-1-hydroxyethyl)-1,3-phenylene Bis(dimethylcarbamate)
63. [3-[2-(tert-butylamino)-1-oxidanyl-ethyl]-5-(dimethylcarbamoyloxy)phenyl] N,n-dimethylcarbamate
64. N,n-dimethylcarbamic Acid [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-[dimethylamino(oxo)methoxy]phenyl] Ester
| Molecular Weight | 367.4 g/mol |
|---|---|
| Molecular Formula | C18H29N3O5 |
| XLogP3 | 1.2 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 8 |
| Exact Mass | 367.21072103 g/mol |
| Monoisotopic Mass | 367.21072103 g/mol |
| Topological Polar Surface Area | 91.3 Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 446 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
For the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.
Bambuterol is a long acting beta2-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline. Bambuterol causes smooth muscle relaxation, resulting in dilation of bronchial passages.
Bronchodilator Agents
Agents that cause an increase in the expansion of a bronchus or bronchial tubes. (See all compounds classified as Bronchodilator Agents.)
R - Respiratory system
R03 - Drugs for obstructive airway diseases
R03C - Adrenergics for systemic use
R03CC - Selective beta-2-adrenoreceptor agonists
R03CC12 - Bambuterol
Absorption
Bioavailability is 20% following oral administration.
Hepatic, extensive. Further metabolized to terbutaline by plasma cholinesterase.
13 hours for bambuterol and 21 hours for the primary active metabolite terbutaline.
The pharmacologic effects of bambuterol are at least in part attributable to stimulation through beta-adrenergic receptors (beta 2 receptors) of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.
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PharmaCompass offers a list of Bambuterol Hydrochloride API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Bambuterol Hydrochloride manufacturer or Bambuterol Hydrochloride supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Bambuterol Hydrochloride manufacturer or Bambuterol Hydrochloride supplier.
PharmaCompass also assists you with knowing the Bambuterol Hydrochloride API Price utilized in the formulation of products. Bambuterol Hydrochloride API Price is not always fixed or binding as the Bambuterol Hydrochloride Price is obtained through a variety of data sources. The Bambuterol Hydrochloride Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Bambec manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Bambec, including repackagers and relabelers. The FDA regulates Bambec manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Bambec API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Bambec manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Bambec supplier is an individual or a company that provides Bambec active pharmaceutical ingredient (API) or Bambec finished formulations upon request. The Bambec suppliers may include Bambec API manufacturers, exporters, distributors and traders.
click here to find a list of Bambec suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.
Pharmaceutical companies submit a Bambec Drug Master File in Korea (Bambec KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Bambec. The MFDS reviews the Bambec KDMF as part of the drug registration process and uses the information provided in the Bambec KDMF to evaluate the safety and efficacy of the drug.
After submitting a Bambec KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Bambec API can apply through the Korea Drug Master File (KDMF).
click here to find a list of Bambec suppliers with KDMF on PharmaCompass.
A Bambec written confirmation (Bambec WC) is an official document issued by a regulatory agency to a Bambec manufacturer, verifying that the manufacturing facility of a Bambec active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Bambec APIs or Bambec finished pharmaceutical products to another nation, regulatory agencies frequently require a Bambec WC (written confirmation) as part of the regulatory process.
click here to find a list of Bambec suppliers with Written Confirmation (WC) on PharmaCompass.
Bambec Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Bambec GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Bambec GMP manufacturer or Bambec GMP API supplier for your needs.
A Bambec CoA (Certificate of Analysis) is a formal document that attests to Bambec's compliance with Bambec specifications and serves as a tool for batch-level quality control.
Bambec CoA mostly includes findings from lab analyses of a specific batch. For each Bambec CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Bambec may be tested according to a variety of international standards, such as European Pharmacopoeia (Bambec EP), Bambec JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Bambec USP).
