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Details:

Rexulti (brexpiprazole) is an partial agonist activity at serotonin 5-HT1A, which is being investigated in combination therapy with sertraline for the treatment of post-traumatic stress disorder (PTSD).


Lead Product(s): Brexpiprazole,Sertraline Hydrochloride

Therapeutic Area: Psychiatry/Psychology Product Name: Rexulti

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: H. Lundbeck AS

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 09, 2024

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Details:

Rexulti (brexpiprazole) is an partial agonist activity at serotonin 5-HT1A, which is investigated in combination therapy with sertraline for the treatment of post-traumatic stress disorder (PTSD).


Lead Product(s): Brexpiprazole,Sertraline Hydrochloride

Therapeutic Area: Psychiatry/Psychology Product Name: Rexulti

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: H. Lundbeck AS

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 07, 2023

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Sertraline hydrochloride potentiates serotonergic activity in the central nervous system through inhibition of neuronal reuptake of serotonin (5-HT). It is indicated for the treatment of MDD, PTSD, PMDD, panic disorder, and social anxiety disorder.


Lead Product(s): Sertraline Hydrochloride

Therapeutic Area: Psychiatry/Psychology Product Name: Sertraline Hydrochloride-Generic

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 12, 2021

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It showed 60 milligrams of SLS-002 to be safe and well tolerated as a monotherapy or with an oral antidepressant.


Lead Product(s): Ketamine Hydrochloride,Venlafaxine,Sertraline Hydrochloride

Therapeutic Area: Psychiatry/Psychology Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 10, 2020

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