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Chemistry

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Also known as: Amiprilose hydrochloride, 56824-20-5, (r)-1-((3ar,5r,6s,6ar)-6-(3-(dimethylamino)propoxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol hydrochloride
Molecular Formula
C14H28ClNO6
Molecular Weight
341.83  g/mol
InChI Key
RJNRORZRFGUAKL-QQIJRPFSSA-N

56824-20-5
1 2D Structure

56824-20-5

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1R)-1-[(3aR,5S,6S,6aR)-6-[3-(dimethylamino)propoxy]-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol;hydrochloride
2.1.2 InChI
InChI=1S/C14H27NO6.ClH/c1-14(2)20-12-11(18-7-5-6-15(3)4)10(9(17)8-16)19-13(12)21-14;/h9-13,16-17H,5-8H2,1-4H3;1H/t9-,10+,11+,12-,13-;/m1./s1
2.1.3 InChI Key
RJNRORZRFGUAKL-QQIJRPFSSA-N
2.1.4 Canonical SMILES
CC1(OC2C(C(OC2O1)C(CO)O)OCCCN(C)C)C.Cl
2.1.5 Isomeric SMILES
CC1(O[C@@H]2[C@H]([C@@H](O[C@@H]2O1)[C@@H](CO)O)OCCCN(C)C)C.Cl
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 1,2-o-isopropylidene-3-o-3'-(n',n'-dimethylamino-n-propyl)-d-glucofuranose

2. 3-o-(3-(dimethylamino)propyl)-1,2-o-(1-methylethylidene)- Alpha-d-glucofuranose

3. Amiprilose

4. Amiprilose Hydrochloride

5. Amprilose

6. Sm 1213

7. Sm-1213

8. Therafectin

2.2.2 Depositor-Supplied Synonyms

1. Amiprilose Hydrochloride

2. 56824-20-5

3. (r)-1-((3ar,5r,6s,6ar)-6-(3-(dimethylamino)propoxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol Hydrochloride

2.3 Create Date
2015-09-21
3 Chemical and Physical Properties
Molecular Weight 341.83 g/mol
Molecular Formula C14H28ClNO6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count7
Exact Mass341.1605153 g/mol
Monoisotopic Mass341.1605153 g/mol
Topological Polar Surface Area80.6 Ų
Heavy Atom Count22
Formal Charge0
Complexity337
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Adjuvants, Immunologic

Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. (See all compounds classified as Adjuvants, Immunologic.)


Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


Antiviral Agents

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)


ABOUT THIS PAGE

Looking for 56824-20-5 / 56824-20-5 API manufacturers, exporters & distributors?

56824-20-5 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of 56824-20-5 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right 56824-20-5 manufacturer or 56824-20-5 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred 56824-20-5 manufacturer or 56824-20-5 supplier.

PharmaCompass also assists you with knowing the 56824-20-5 API Price utilized in the formulation of products. 56824-20-5 API Price is not always fixed or binding as the 56824-20-5 Price is obtained through a variety of data sources. The 56824-20-5 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

56824-20-5

Synonyms

Amiprilose hydrochloride, (r)-1-((3ar,5r,6s,6ar)-6-(3-(dimethylamino)propoxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol hydrochloride

Cas Number

56824-20-5

56824-20-5 Manufacturers

A 56824-20-5 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of 56824-20-5, including repackagers and relabelers. The FDA regulates 56824-20-5 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. 56824-20-5 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

56824-20-5 Suppliers

A 56824-20-5 supplier is an individual or a company that provides 56824-20-5 active pharmaceutical ingredient (API) or 56824-20-5 finished formulations upon request. The 56824-20-5 suppliers may include 56824-20-5 API manufacturers, exporters, distributors and traders.

56824-20-5 GMP

56824-20-5 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of 56824-20-5 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right 56824-20-5 GMP manufacturer or 56824-20-5 GMP API supplier for your needs.

56824-20-5 CoA

A 56824-20-5 CoA (Certificate of Analysis) is a formal document that attests to 56824-20-5's compliance with 56824-20-5 specifications and serves as a tool for batch-level quality control.

56824-20-5 CoA mostly includes findings from lab analyses of a specific batch. For each 56824-20-5 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

56824-20-5 may be tested according to a variety of international standards, such as European Pharmacopoeia (56824-20-5 EP), 56824-20-5 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (56824-20-5 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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