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    Zavegepant HCl

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    Moehs Iberica Sl

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    Virtual BoothMoehs Group, a reference company in the production of pharmaceutical active ingredients.

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    DMF Number : 41470

    Submission : 2025-03-11

    Status : Active

    Type : II

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    Looking for 1337918-83-8 / Vazegepant API manufacturers, exporters & distributors?

    Vazegepant manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Vazegepant API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Vazegepant manufacturer or Vazegepant supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Vazegepant manufacturer or Vazegepant supplier.

    PharmaCompass also assists you with knowing the Vazegepant API Price utilized in the formulation of products. Vazegepant API Price is not always fixed or binding as the Vazegepant Price is obtained through a variety of data sources. The Vazegepant Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Vazegepant

    Synonyms

    Bms-742413, Bhv-3500, Zavegepant [usan], Odu3zaz94j, Bms-742413-01, 1337918-83-8

    Cas Number

    1337918-83-8

    Unique Ingredient Identifier (UNII)

    ODU3ZAZ94J

    About Vazegepant

    Zavegepant is a highly soluble small molecule calcitonin gene related peptide (CGRP) receptor antagonist, with potential analgesic and immunomodulating activities. Upon administration, zavegepant targets, binds to and inhibits the activity of CGRP receptors located on mast cells in the brain. This may inhibit neurogenic inflammation caused by trigeminal nerve release of CGRP. In addition, by blocking the CGRP receptors located in smooth muscle cells within vessel walls, zavegepant inhibits the pathologic dilation of intracranial arteries. Zavegepant, by blocking the CGRP receptors, also suppresses the transmission of pain by inhibiting the central relay of pain signals from the trigeminal nerve to the caudal trigeminal nucleus. Altogether, this may relieve migraine. As CGRP receptors induce the release of pro-inflammatory mediators, such as interleukin-6 (IL-6), from inflammatory cells, zavegepant may prevent an IL-6-mediated inflammatory response. Zavegepant may also inhibit the CGRP-mediated induction of eosinophil migration and the stimulation of beta-integrin-mediated T cell adhesion to fibronectin at the site of inflammation, and may abrogate the CGRP-mediated polarization of the T cell response towards the pro-inflammatory state characterized by Th17 and IL-17. This may improve lung inflammation and oxygenation, prevent edema, and further lung injury. CGRP, a 37 amino-acid peptide expressed in and released from a subset of polymodal primary sensory neurons of the trigeminal ganglion and nerve fibers projecting to the airways and by pulmonary neuroendocrine cells, plays an important role in pain transmission, inflammation, and neurogenic vasodilatation. It is released upon acute lung injury and upregulation of transient receptor potential (TRP) channels.

    Zavegepant HCl Manufacturers

    A Zavegepant HCl manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Zavegepant HCl, including repackagers and relabelers. The FDA regulates Zavegepant HCl manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Zavegepant HCl API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Zavegepant HCl manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Zavegepant HCl Suppliers

    A Zavegepant HCl supplier is an individual or a company that provides Zavegepant HCl active pharmaceutical ingredient (API) or Zavegepant HCl finished formulations upon request. The Zavegepant HCl suppliers may include Zavegepant HCl API manufacturers, exporters, distributors and traders.

    click here to find a list of Zavegepant HCl suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Zavegepant HCl USDMF

    A Zavegepant HCl DMF (Drug Master File) is a document detailing the whole manufacturing process of Zavegepant HCl active pharmaceutical ingredient (API) in detail. Different forms of Zavegepant HCl DMFs exist exist since differing nations have different regulations, such as Zavegepant HCl USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Zavegepant HCl DMF submitted to regulatory agencies in the US is known as a USDMF. Zavegepant HCl USDMF includes data on Zavegepant HCl's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Zavegepant HCl USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Zavegepant HCl suppliers with USDMF on PharmaCompass.

    Zavegepant HCl Manufacturers | Traders | Suppliers

    Zavegepant HCl Manufacturers, Traders, Suppliers 1
    89

    We have 1 companies offering Zavegepant HCl

    Get in contact with the supplier of your choice:

    1. Moehs Iberica
    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.