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Chemistry

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Also known as: 865759-25-7, Syr-472, Trelagliptin(syr-472), Trelagliptin [usan], Q836owg55h, Chembl1650443
Molecular Formula
C18H20FN5O2
Molecular Weight
357.4  g/mol
InChI Key
IWYJYHUNXVAVAA-OAHLLOKOSA-N
FDA UNII
Q836OWG55H

Trelagliptin
Trelagliptin is under investigation in clinical trial NCT03555591 (Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Patients With Type 2 Diabetes Mellitus").
1 2D Structure

Trelagliptin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]-4-fluorobenzonitrile
2.1.2 InChI
InChI=1S/C18H20FN5O2/c1-22-17(25)8-16(23-6-2-3-15(21)11-23)24(18(22)26)10-13-7-14(19)5-4-12(13)9-20/h4-5,7-8,15H,2-3,6,10-11,21H2,1H3/t15-/m1/s1
2.1.3 InChI Key
IWYJYHUNXVAVAA-OAHLLOKOSA-N
2.1.4 Canonical SMILES
CN1C(=O)C=C(N(C1=O)CC2=C(C=CC(=C2)F)C#N)N3CCCC(C3)N
2.1.5 Isomeric SMILES
CN1C(=O)C=C(N(C1=O)CC2=C(C=CC(=C2)F)C#N)N3CCC[C@H](C3)N
2.2 Other Identifiers
2.2.1 UNII
Q836OWG55H
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Syr-472

2. Trelagliptin Succinate

2.3.2 Depositor-Supplied Synonyms

1. 865759-25-7

2. Syr-472

3. Trelagliptin(syr-472)

4. Trelagliptin [usan]

5. Q836owg55h

6. Chembl1650443

7. 865759-25-7 (free Base)

8. (r)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)methyl)-4-fluorobenzonitrile

9. Trelagliptin (usan)

10. (r)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)methyl)-4-fluorobenzonitrile.

11. 2-[[6-[(3r)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]-4-fluorobenzonitrile

12. Trelagliptin [usan:inn]

13. Unii-q836owg55h

14. Trelagliptin(syr472)

15. Trelagliptin [mi]

16. Trelagliptin [inn]

17. Schembl175726

18. Trelagliptin [who-dd]

19. Dtxsid00235678

20. Ex-a470

21. Chebi:134715

22. Bdbm50335784

23. Mfcd22572746

24. Nsc802901

25. S7513

26. Zinc34505198

27. Akos026674097

28. Ccg-268122

29. Cs-1041

30. Db15323

31. Nsc-802901

32. Ncgc00378845-01

33. Ac-30279

34. As-75009

35. Hy-15408

36. A3889

37. D10178

38. A855303

39. Q27287099

40. 2-((6-((3r)-3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)- Yl)methyl)-4-fluorobenzonitrile

41. 2-((6-((3r)-3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)methyl)-4-fluorobenzonitrile

42. 2-({6-[(3r)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}methyl)-4-fluorobenzonitrile

43. 2-[[6-[(3~{r})-3-azanylpiperidin-1-yl]-3-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]methyl]-4-fluoranyl-benzenecarboni

44. 2-[[6-[(3~{r})-3-azanylpiperidin-1-yl]-3-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]methyl]-4-fluoranyl-benzenecarbonitrile

45. 2-[6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2h-pyrimidin-1-ylmethyl]-4-fluorobenzonitrile

46. 6rl

47. Benzonitrile, 2-((6-((3r)-3-amino-1-piperidinyl)-3,4-dihydro-3-methyl-2,4-dioxo-1(2h)- Pyrimidinyl)methyl)-4-fluoro-

48. Benzonitrile, 2-((6-((3r)-3-amino-1-piperidinyl)-3,4-dihydro-3-methyl-2,4-dioxo-1(2h)-pyrimidinyl)methyl)-4-fluoro-

2.4 Create Date
2007-03-27
3 Chemical and Physical Properties
Molecular Weight 357.4 g/mol
Molecular Formula C18H20FN5O2
XLogP30.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass357.16010306 g/mol
Monoisotopic Mass357.16010306 g/mol
Topological Polar Surface Area93.7 Ų
Heavy Atom Count26
Formal Charge0
Complexity657
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API SUPPLIERS

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01

Beijing Lunarsun Pharmaceutical Co...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Wuhan Monad Pharmaceutical Technol...

China

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Waterstone Pharmaceuticals Inc.

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Waterstone Pharmaceuticals Inc.

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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TRELAGLIPTIN

About the Company : Beijing Lunarsun pharma is a professional manufacturer of API and intermediates. The factory is approved by US FDA. According to EU and US FDA's requirement, we supply following AP...

Beijing Lunarsun pharma is a professional manufacturer of API and intermediates. The factory is approved by US FDA. According to EU and US FDA's requirement, we supply following APIs and their intermediates with good quality and competitive price: Aztreonam,Doripenem, Dronedarone Hcl ,Erlotinib HCL, Febuxostat,Gemcitabine HCL, Ivabradine, Imatinib mesylate, Mecobalamin,Moxifloxacin, Nelarabine,Pemetrexed disodium, Posaconazole, Temozolomide, Voriconazole, Tebipenem pivoxil.NOTE: Products covered by valid patents in any country are not offered or supplied to these countries for commercial purpose.
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TRELAGLIPTIN

About the Company : Waterstone is an international pharmaceutical company with its main operations in China. The company is focused in discovery, development and commercialization of innovative drug...

Waterstone is an international pharmaceutical company with its main operations in China. The company is focused in discovery, development and commercialization of innovative drugs for the treatment of liver and gastrointestinal diseases. With venture capital investments from internationally well-known firms such as BAR Capital, CID Group, Orbimed, and Acorn Camps, the company has established fully integrated capabilities from R&D, API & Finished Drug Product manufacturing to sales/marketing. The company has a strong management team with cross-border experience and advisors with expertise in drug discovery, regulatory, and GMP manufacturing. On top of the forty marked drugs in China, the company has also built a rich pipeline including Drug Master Files with U.S. FDA , candidates in phase II/III clinical tries with cFDA, and several novel preclinical stage antiviral and oncology candidates
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Trelagliptin

About the Company : Wuhan Monad Medicine Tech Co.,LTD has a registered capital of 1 million yuan and is one of the most dynamic foreign trade companies in the Chinese market. We have a pharmaceutical ...

Wuhan Monad Medicine Tech Co.,LTD has a registered capital of 1 million yuan and is one of the most dynamic foreign trade companies in the Chinese market. We have a pharmaceutical raw material production plant and a reagent R&D center. We now have the most complete product line. In addition, we have developed and produced tens of thousands of reagents. We also have the business of custom synthesis of various organic compounds as a supplement. We can synthesize almost all chemicals. Our goal is to survive by quality and develop by credit.
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06-Jan-2022
07-Jan-2025
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INTERMEDIATE SUPPLIERS

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CAS Number : 334618-23-4

End Use API : Trelagliptin

About The Company : We are into manufacturing of bulk drug Intermediates and Active Pharmaceutical Ingredients (API). Our core competence is contract manufacturing for our clients ...

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CAS Number : 309956-78-3

End Use API : Trelagliptin

About The Company : We are into manufacturing of bulk drug Intermediates and Active Pharmaceutical Ingredients (API). Our core competence is contract manufacturing for our clients ...

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CAS Number : 109113-72-6

End Use API : Trelagliptin

About The Company : We are into manufacturing of bulk drug Intermediates and Active Pharmaceutical Ingredients (API). Our core competence is contract manufacturing for our clients ...

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CAS Number : 666816-98-4

End Use API : Trelagliptin

About The Company : We are into manufacturing of bulk drug Intermediates and Active Pharmaceutical Ingredients (API). Our core competence is contract manufacturing for our clients ...

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05

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CAS Number : 865759-24-6

End Use API : Trelagliptin

About The Company : Bulat Pharmaceutical is a fast growing pharmaceutical company, founded in the year 2017, Bulat Pharmaceutical is engaged in the manufacturing and sales of high ...

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CAS Number : 421552-12-7

End Use API : Trelagliptin

About The Company : Bulat Pharmaceutical is a fast growing pharmaceutical company, founded in the year 2017, Bulat Pharmaceutical is engaged in the manufacturing and sales of high ...

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CAS Number : 865759-24-6

End Use API : Trelagliptin

About The Company : Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-...

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CAS Number : 334618-23-4

End Use API : Trelagliptin

About The Company : Based on the excellent enzymatic technology platform, Enzymaster Chemical applies innovative technology to realize its commercial production of chiral compounds...

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CAS Number : 4318-56-3

End Use API : Trelagliptin

About The Company : Guangzhou Topwork Chemical Co., Ltd. Specializes in manufacturing corticosteroid and relative intermediates. We provide high quality products and excellent serv...

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CAS Number : 4318-56-3

End Use API : Trelagliptin

About The Company : Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and technical service of APIs, pharmaceutical intermediates...

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01

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Trelagliptin Impurity 10

CAS Number : 2204313-59-5

Quantity Per Vial :

Sale Unit :

Price :

Details : In stock

Monograph :

Storage :

Code/Batch No : T0089.10

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02

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Trelagliptin Impurity 12

CAS Number : 2206135-35-3 (free base)

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Code/Batch No : T0089.12

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Trelagliptin Impurity 16

CAS Number : 112399-50-5

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Code/Batch No : T0089.16

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Trelagliptin Impurity 22

CAS Number :

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Storage :

Code/Batch No : T0089.22

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05

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Trelagliptin Impurity 5

CAS Number : 1917324-13-0

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Code/Batch No : T0089.05

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06

Aus. Peptide Conference
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Trelagliptin Impurity 56

CAS Number : 1938080-43-3

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Details : In stock

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Storage :

Code/Batch No : T0089.56

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Trelagliptin Impurity 57

CAS Number :

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Price :

Details : In stock

Monograph :

Storage :

Code/Batch No : T0089.57

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Trelagliptin Impurity 58

CAS Number :

Quantity Per Vial :

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Price :

Details : In stock

Monograph :

Storage :

Code/Batch No : T0089.58

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Looking for 865759-25-7 / Trelagliptin API manufacturers, exporters & distributors?

Trelagliptin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Trelagliptin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Trelagliptin manufacturer or Trelagliptin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Trelagliptin manufacturer or Trelagliptin supplier.

PharmaCompass also assists you with knowing the Trelagliptin API Price utilized in the formulation of products. Trelagliptin API Price is not always fixed or binding as the Trelagliptin Price is obtained through a variety of data sources. The Trelagliptin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Trelagliptin

Synonyms

865759-25-7, Syr-472, Trelagliptin(syr-472), Trelagliptin [usan], Q836owg55h, Chembl1650443

Cas Number

865759-25-7

Unique Ingredient Identifier (UNII)

Q836OWG55H

About Trelagliptin

Trelagliptin is under investigation in clinical trial NCT03555591 (Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Patients With Type 2 Diabetes Mellitus").

Trelagliptin Manufacturers

A Trelagliptin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Trelagliptin, including repackagers and relabelers. The FDA regulates Trelagliptin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Trelagliptin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Trelagliptin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Trelagliptin Suppliers

A Trelagliptin supplier is an individual or a company that provides Trelagliptin active pharmaceutical ingredient (API) or Trelagliptin finished formulations upon request. The Trelagliptin suppliers may include Trelagliptin API manufacturers, exporters, distributors and traders.

click here to find a list of Trelagliptin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Trelagliptin GMP

Trelagliptin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Trelagliptin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Trelagliptin GMP manufacturer or Trelagliptin GMP API supplier for your needs.

Trelagliptin CoA

A Trelagliptin CoA (Certificate of Analysis) is a formal document that attests to Trelagliptin's compliance with Trelagliptin specifications and serves as a tool for batch-level quality control.

Trelagliptin CoA mostly includes findings from lab analyses of a specific batch. For each Trelagliptin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Trelagliptin may be tested according to a variety of international standards, such as European Pharmacopoeia (Trelagliptin EP), Trelagliptin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Trelagliptin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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