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    Apaziquone

    ACTIVE PHARMA INGREDIENTS

    DEVELOPMENTS

    INTERMEDIATES

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    Looking for 114560-48-4 / Apaziquone API manufacturers, exporters & distributors?

    Apaziquone manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Apaziquone API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Apaziquone manufacturer or Apaziquone supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Apaziquone manufacturer or Apaziquone supplier.

    API | Excipient name

    Apaziquone

    Synonyms

    114560-48-4, Eoquin, Qapzola, Eo-9, Nor-701, Nsc-382459

    Cas Number

    114560-48-4

    Unique Ingredient Identifier (UNII)

    H464ZO600O

    About Apaziquone

    Apaziquone is an indolequinone bioreductive prodrug and analog of mitomycin C with potential antineoplastic and radiosensitization activities. Apaziquone is converted to active metabolites in hypoxic cells by intracellular reductases, which are present in greater amounts in hypoxic tumor cells. The active metabolites alkylate DNA, resulting in apoptotic cell death. This agent displays selectivity activity towards both hypoxic solid tumors, which exhibits higher expression of cytochrome P450 reductase, and well-oxygenated malignant cells that overexpress the bioreductive enzyme NQO1 (NAD(P)H: quinone oxidoreductase). Apaziquone may selectively sensitize hypoxic tumor cells to radiocytotoxicity.

    Apaziquone Manufacturers

    A Apaziquone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Apaziquone, including repackagers and relabelers. The FDA regulates Apaziquone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Apaziquone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    Apaziquone Suppliers

    A Apaziquone supplier is an individual or a company that provides Apaziquone active pharmaceutical ingredient (API) or Apaziquone finished formulations upon request. The Apaziquone suppliers may include Apaziquone API manufacturers, exporters, distributors and traders.

    click here to find a list of Apaziquone suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

    Apaziquone USDMF

    A Apaziquone DMF (Drug Master File) is a document detailing the whole manufacturing process of Apaziquone active pharmaceutical ingredient (API) in detail. Different forms of Apaziquone DMFs exist exist since differing nations have different regulations, such as Apaziquone USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Apaziquone DMF submitted to regulatory agencies in the US is known as a USDMF. Apaziquone USDMF includes data on Apaziquone's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Apaziquone USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Apaziquone suppliers with USDMF on PharmaCompass.

    Apaziquone Manufacturers | Traders | Suppliers

    Apaziquone Manufacturers, Traders, Suppliers 1
    70

    We have 1 companies offering Apaziquone

    Get in contact with the supplier of your choice:

    1. Spectrum Pharmaceuticals
    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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