Key Highlights: Cholesterol Efflux MediatorTM VAR 200 on target to begin Phase 2a clinical trial in patients with diabetic kidney disease H1-2024
Initiation of Phase 2a trial first half 2024 with Cholesterol Efflux Mediator VAR 200 in diabetic kidney disease is a key milestone for ZyVersa.
Activation of the inflammasome/ASC speck pathway has a vital role in synaptic degeneration in Alzheimers Disease (AD).
ZyVersa Therapeutics has tapped Australia’s George Clinical to run a phase 2a clinical trial for a diabetic kidney disease treatment.
BMF-219 is an investigational novel covalent menin inhibitor developed to regenerate insulin-producing beta cells with the aim to cure diabetes In a poster presentation on Thursday, Dec. 7th at...
NLRP3 Inflammasome Inhibition Alleviates Neurological Impairment in the Brain of MS Mouse Model, Reinforcing Published Data for IC 100 in MS Mouse Model.
Cholesterol accumulation in the kidneys' podocytes from impaired efflux out of cells is one of the hallmarks of kidney injury in chronic kidney disease.
Activation of multiple inflammasome pathways contributes to pathological inflammation in neurodegenerative (œCNS) diseases, such as amyotrophic lateral sclerosis (œALS)This study showed that NLRP3...
WESTON, Fla., July 24, 2023 (GLOBE NEWSWIRE) -- ZyVersa Therapeutics, Inc. (Nasdaq: ZVSA, or œZyVersa or œthe Company), a clinical stage specialty biopharmaceutical company developing...
Liver fibrosis is a progressive form of chronic liver injury mediated by persistent NLRP3 inflammasome activation in liver cells called hepatic stellate cells (€œHSCs€), which leads to the development...