The FDA has approved atezolizumab (Tecentriq) plus cobimetinib (Cotellic) and vemurafenib (Zelboraf) for the treatment of patients with BRAF V600 mutation-positive advanced melanoma, according to Genentech, atezolizumab’s developer.
Back in December, Roche unveiled a win for its cocktail of Tecentriq, Cotellic and Zelboraf in patients with BRAF V600-mutated melanoma. And details of that win are here.
Roche's phase III IMspire150 study of Tecentriq plus Cotellic & Zelboraf for previously untreated BRAF V600 mutation-positive advanced melanoma meets primary endpoint
The Health Service Executive (HSE) has granted reimbursement for Pierre Fabre’s Braftovi (encorafenib) and Mektovi (binimetinib) combination in Ireland.
One class of proteins was at the heart of nearly $100 billion worth oncology M&A over the past decade, according to a new report.
To little surprise, Exelixis’ Cotellic — known chemically as cobimetinib — in combination with Roche’s Tecentriq, has failed a late-stage study as a frontline treatment for patients with a form of advanced melanoma.
Braftovi (encorafenib), a BRAF kinase inhibitor developed by Pierre Fabre, has been awarded approval in combination with Mektovi (binimetinib) by UK drug watchdog NICE for the treatment of unresectable or metastatic melanoma in adult patients with a BRAF V600 mutation, it has emerged.
Novartis’ cancer combination Tafinlar and Mekinist has been approved by the EMA for adjuvant treatment of advanced melanoma in order to prevent disease recurrence.
Twenty years after it began, Array BioPharma has its first two drug approvals, a cancer drug combo that'll transform care for certain melanoma patients, the company's CEO says. But they'll face a couple of heavyweight pharmas in the field.