PALO ALTO, Calif., Nov. 13, 2020 /PRNewswire/ -- twoXAR Pharmaceuticals, a drug discovery and development company focused on bringing first-in-class small molecules to market, today announced that two novel leads for the potential treatment of non-alcoholic steatohepatitis (NASH), TXR-611 and TXR-612, demonstrated significant efficacy and excellent tolerability in preclinical studies. TXR-611 and TXR-612 represent two different novel mechanisms of actions. The overall timing to complete predictions, select hits and begin in vivo testing took a total of four weeks, significantly faster than traditional drug discovery processes. The data was presented at The Liver Meeting Digital Experience™ 2020, the Annual Meeting of the American Association for the Study of Liver Diseases (AASLD). The full poster is available at www.twoxar.com.
MOUNTAIN VIEW, Calif., June 22, 2020 /PRNewswire/ -- twoXAR Pharmaceuticals, a drug discovery and development company focused on bringing first-in-class small molecules to market, today announced that preclinical data for its investigational treatment TXR-311 with a novel MOA demonstrated significant efficacy and good tolerability in in vivo studies for the potential treatment of hepatocellular carcinoma (HCC), with results comparable to sorafenib, today's standard-of-care. The data was presented at the American Association for Cancer Research (AACR) Virtual Annual Meeting II. The full poster and accompanying audio of the data is available at www.twoxar.com.
1ST Biotherapeutics, Inc., a clinical-stage biotechnology company focused on neurodegenerative diseases, immuno-oncology, and orphan diseases, and twoXAR Pharmaceuticals, a company that discovers drugs with AI, today announced the companies will advance three novel drug leads for the potential treatment of glioblastoma into in vivo efficacy testing less than one year from launching the drug discovery collaboration.
SK Biopharmaceuticals and twoXAR Sign Collaboration Agreement to Discover and Develop First-In-Class Treatments for Non-Small Cell Lung Cancer
SEONGNAM, South Korea & MOUNTAIN VIEW, Calif.--(BUSINESS WIRE)--1ST Biotherapeutics, Inc., a preclinical-stage biotechnology company focused on neurodegenerative diseases, immuno-oncology, and orphan diseases, and twoXAR, Inc., an artificial intelligence (AI)-driven biopharmaceutical company, today announced an agreement to jointly discover and develop novel, efficacious treatments to address unmet medical needs in glioblastoma multiforme (“glioblastoma”).
TwoXar, a biopharmaceutical startup that uses artificial intelligence (AI) to identify and develop new medicines, has raised $10 million in a series A round of funding led by SoftBank’s early-stage venture capital firm, SoftBank Ventures, with participation from Andreessen Horowitz and Braintree founder Bryan Johnson’s OS Fund.
TwoXAR has teamed up with the University of Chicago to apply its software-driven approach to drug discovery to the identification of potential treatments for atherosclerosis. The IT-enabled R&D shop, which was the first firm to receive funding from Andreessen Horowitz’s $200 million biotech fund, will identify candidates for preclinical testing by its academic collaborator.