Background/Purpose: This study was conducted to evaluate the extent to which disease modifying antirheumatic medications (DMARDs) used as part of triple therapy for treatment of rheumatoid arthritis (RA) including methotrexate, sulfasalazine and hydroxychloroquine are associated with incident fractures in postmenopausal women with RA.
Mesalamine Delayed-Release Capsules are an aminosalicylate indicated for the treatment of mildly to moderately active ulcerative colitis in patients 5 years of age and older, and for the maintenance of remission of ulcerative colitis in adults.
In a bid to promote patient safety, the Drugs Controller General of India (DCGI) has directed all state drug controllers in the country to take steps to ensure that manufacturers of seven formulations-- cefotaxime, ofloxacin, tranexamic acid, quetiapine, sulfasalazine, sodium valproate and cefixime-- mention newly identified adverse reactions in the package insert of the drugs.
Health Canada Issues Recall of Pharmascience`s PMS-Sulfasalazine 500 mg Tablet USP
The first study (SIRROUND-T), in patients who were refractory to or intolerant to one or more anti-tumor necrosis factor (TNF) agents, demonstrated that sirukumab met the primary endpoint showing significant improvement in the signs and symptoms of moderately to severely active RA compared to placebo. The second study (SIRROUND-H), a head-to-head study in patients who were refractory to or intolerant to methotrexate (MTX), demonstrated that sirukumab monotherapy met the first of two co-primary endpoints showing significant improvement in disease activity compared to adalimumab monotherapy.