Seismic Therapeutic Presents Preclinical Data on S-1117, its Novel Pan-IgG Protease Addressing Multiple Pathogenic Mechanisms in Autoimmune Disease, at American Academy of Neurology (AAN) 2024
Seismic to Present Preclinical Data for Novel Immunoglobulin Sculpting Enzyme
Seismic Therapeutic Closes $121 Million Series B Financing
Seismic Therapeutic has secured a series B of significant magnitude, with $121 million pitched in by new investor Amgen Ventures in a round aimed at pushing two immunology programs into the clinic.
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Seismic Therapeutic, Inc., the machine learning immunology company, today announced nine poster presentations supporting the company’s emerging pipeline of novel biologics derived from its proprietary IMPACT platform to treat autoimmune diseases at the 23rd Annual Meeting of the Federation of Clinical Immunology Societies (FOCIS) taking place on June 20-23 in Boston, MA. Seismic’s immunoglobin (Ig) sculpting enzymes and dual-cell bidirectional (DcB) antibody programs will be highlighted in these presentations, demonstrating the design of therapeutics to address unmet medical needs for diseases involving dysregulation of humoral immunity and cell-mediated immunity, the two arms of the adaptive immune system. In particular, results from novel in vitro human assays to characterize inhibitory checkpoint receptor agonism will be presented along with activity readouts in in vivo humanized mouse models with Seismic’s lead DcB antibody program, in comparison to current benchmarks.
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Seismic Therapeutic, Inc., the machine learning immunology company, today announced the presentation of preclinical data that describe the application of the company’s IMPACT platform at PEGS Boston 2023, taking place on May 15-19. The three poster presentations outline how Seismic’s IMPACT platform enables the parallel optimization of multiple parameters, including predicting and removing B and T cell epitopes, augmenting drug-like properties and retaining protein function, to create novel drug candidates across the immunoglobin (Ig) sculpting enzymes and dual-cell bidirectional (DcB) antibody product areas. Seismic is designing novel biologics derived from the IMPACT platform to address unmet medical needs for diseases involving humoral immunity and cell-mediated immunity, the two arms of the adaptive immune system.
Seismic Therapeutic Announces Presentation of Preclinical Data for Immunoglobin Sculpting Enzyme and Dual-Cell Bidirectional Antibody Programs at IMMUNOLOGY 2023
Seismic Therapeutic Appoints Melanie Manning as Chief People Officer
WATERTOWN, Mass.--(BUSINESS WIRE)--Seismic Therapeutic, Inc., a biotechnology company advancing machine learning for immunology drug development, today announced the appointment of Maude Tessier, PhD, as Chief Business Officer. Dr. Tessier brings over 16 years of company building experience with a multi-disciplinary background in business development, corporate strategy, corporate communications, IP management, and portfolio and program management in public and private biotechnology, pharmaceutical and academic organizations.
WATERTOWN, Mass.--(BUSINESS WIRE)--Seismic Therapeutic, Inc., a biotechnology company advancing machine learning for immunology drug development, today announced the appointment of Eric Larson as Senior Vice President of Finance and Heather Vital as Vice President of R&D Strategy. These experienced business leaders join Seismic at a pivotal time for the company as it approaches the next stage of growth to build a pipeline of novel biologics to treat autoimmune diseases.