Novartis Obtains Approval for Pediatric Chronic Heart Failure for Angiotensin
It gives us great pleasure to announce that the USDMF for Sacubitril Sodium has been submitted to the USFDA. With an innovative development strategy, our team of experts
The price of top selling cardiac arrest drug sacubitril/valsartan sold by Swiss pharmaceutical company Novartis and its partners in India is expected fall as much as 60% with several Indian drugmakers gearing up to launch its generic version soon after the Delhi High Court cleared the decks for Indian generic makers by staying Novartis patents on the supra complex compound.
Dr Reddy's Laboratories on Wednesday said it has reduced the price of its cardiovascular drug Cidmus. The drug comprises combination of sacubitril and valsartan and is indicated for heart failure patients.
The Delhi High Court on Wednesday reserved the order on Natco Pharma's writ petition over the grant of a patent to Novartis by the Indian Patent Office (IPO) for its top selling heart failure therapy Vymada, sold internationally as Entresto, till Thursday.
Major companies including Natco, Cipla, Torrent, Lupin, Sun Pharma and USV are readying plans to enter the Rs 24,000-crore space to get a slice of the opportunity, with Swiss major Novartis's blockbuster cardiology drug losing patent protection in January.
As blockbuster heart failure drug Entresto inches toward a patent cliff, Novartis is calling on the FDA—again—to keep early-bird generics at bay.
Delhi HC restrains generic firms from making, selling patent drug of Novartis
Novartis today announced that Entresto® (sacubitril/valsartan) has received a new indication in China for the treatment of patients with essential hypertension, a disease affecting approximately 245 million adults in the country1. This National Medical Products Administration (NMPA) decision follows the 2017 approval of Entresto for the treatment of heart failure with reduced ejection fraction (HFrEF).
In patients with advanced HF, sacubitril/valsartan was not superior to valsartan for reducing N-terminal pro-B natriuretic peptide levels at 24 weeks, according to the results of the LIFE trial.