Ironwood spies new frontier for $1B drug in exploratory trial
Incyte Announces New Data from Phase 2 Study Evaluating Ruxolitinib Cream
Karyopharm Shares Data at ASH 2023 Showing Strong SVR and TSS Durability
As several new JAK inhibitors threaten Incyte’s bread-and-butter Jakafi in myelofibrosis, the company is busy advancing new regimens ahead of the drug’s 2028 patent cliff.
Incyte Announces New Data for Ruxolitinib Cream (Opzelura®) in Children with Atopic Dermatitis
New Long-Term Data from Incyte Phase 3 TRuE-V Program Demonstrates Efficacy of Continued Treatment with Opzelura® (Ruxolitinib) Cream in Nonsegmental Vitiligo Patients
July 11 (Reuters) - Incyte Corp (INCY.O) said on Tuesday its cream to treat a type of skin condition in children between the age of two to twelve met the primary goal in a late-stage study, sending the company's shares up 4% in after-market trading.
The addition of the MDM2 inhibitor navtemadlin (formerly KRT-232) to ruxolitinib (Jakafi) led to clinically meaningful improvements in spleen volume reduction (SVR) among patients with primary or secondary TP53 wild-type myelofibrosis who had a suboptimal response to ruxolitinib, according to findings from the phase 1/2 KRT-232-109 study (NCT04485260) presented during the 2023 European Hematology Association (EHA) Congress.
LEATHERHEAD, England--(BUSINESS WIRE)--Incyte Biosciences UK today announced that the Medicines and Healthcare Products Regulatory Agency (MHRA) has granted marketing authorisation for Opzelura® (ruxolitinib) cream 15mg/g for the treatment of non-segmental vitiligo with facial involvement in adults and adolescents from 12 years of age. Opzelura is the first and only approved treatment in the United Kingdom (UK) to offer eligible patients with non-segmental vitiligo support for repigmentation. The MHRA decision follows the European Commission approval1 earlier in April.