Brussels (Belgium), 9 September 2022 – 07:00 (CEST) – UCB and Amgen, global biopharmaceutical companies, today presented abstracts of three post-hoc analyses focusing on 3D modelling techniques that highlight significant cortical and trabecular bone improvements in patients treated with romosozumab. The data were presented along with additional 17 abstracts, at the American Society for Bone and Mineral Research (ASBMR) 2022 Annual Congress, taking place from 9th – 12th September in Austin, Texas, USA.
ATLANTA -- New research presented at ACR Convergence, the American College Rheumatology's annual meeting, reveals that romosozumab, an osteoporosis drug, produces substantial gains in bone mineral density in the hip and lumbar spine within one year, and that transitioning patients to a potent antiresorptive drug can lead to even more bone density gains (ABSTRACT #1973).
Romosozumab, a specific inhibitor of sclerostin, is a unique approach to therapy for postmenopausal osteoporosis and related disorders. The elucidation of sclerostin deficiency as the molecular defect of syndromes of high bone mass with normal quality, and the pivotal role of sclerostin as a mediator of osteoblastic activity and bone formation, provided the platform for the evaluation of inhibitors of sclerostin to activate bone formation. An extensive preclinical program and 2 large fracture endpoint trials with romosozumab, a sclerostin-binding antibody, have been completed. This review will highlight the results of those studies and describe the current status of romosozumab as a potential therapy for osteoporosis.
Brussels, Belgium – 4 June 2020 – UCB, a global biopharmaceutical company, today announced significant new data on CIMZIA® (certolizumab pegol), EVENITY® (romosozumab) and its investigational IL-17A and IL-17F inhibitor, bimekizumab, that are being presented at the Annual European Congress of Rheumatology (EULAR) 2020. With a total of 14 accepted abstracts and five accepted as oral presentations across multiple rheumatology solutions, UCB’s research is set to take center stage at this year’s virtual congress.
THOUSAND OAKS, Calif., April 30, 2020 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced financial results for the first quarter of 2020 and discussed the company's response to the COVID-19 pandemic.
Amgen EVENITY (Romosozumab-aqqg Injection) Receives Supplemental Approval in US
UCB and Amgen have finally claimed European approval for their osteoporosis drug Evenity, which becomes the first new drug for the disease in the EU since 2010.
UCB and Amgen have announced that following a re-examination procedure, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended its osteoporosis drug, Evenity (romosozumab).
Amgen (NASDAQ:AMGN) and UCB (Euronext Brussels: UCB) today announced that following a re-examination procedure, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion recommending Marketing Authorization for EVENITY® (romosozumab) for the treatment of severe osteoporosis in postmenopausal women at high risk of fracture and with no history of myocardial infarction or stroke. EVENITY is a novel bone-builder with a dual effect that increases bone formation and to a lesser extent reduces bone resorption (or bone loss).
The European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP) on Friday adopted a negative opinion for UCB Pharma’s osteoporosis treatment Evenity (romosozumab), which was approved by the US Food and Drug Administration (FDA) in April.