Renovion Completes Enrollment in Phase 2 CLIMB Study in Bronchiectasis
First Patient Enrolled in Phase 3 Clinical Trial Evaluating ARINA-1 in Lung Transplant
Renovion has enrolled the first subject in a Phase II clinical trial of investigational nebulised therapy, ARINA-1, for the treatment of adult non-cystic fibrosis bronchiectasis (NCFBE) patients.
CHAPEL HILL, N.C. & MIAMI--(BUSINESS WIRE)--Renovion and COPD Foundation Joint Release – Renovion, Inc. has announced that the first patient has been enrolled in a Phase 2 clinical study evaluating ARINA-1, an investigational nebulized therapy, to treat adults with non-CF bronchiectasis (NCFBE) (NCT05495243).
CHAPEL HILL, N.C.--(BUSINESS WIRE)--Renovion, Inc., a clinical-stage pharmaceutical company focused on developing treatments for serious chronic inflammatory lung diseases with high unmet needs, announced today that they have received a Study May Proceed Letter from the U.S. Food and Drug Administration (FDA) for a Phase 3 clinical trial to investigate ARINA-1 in the prevention of Bronchiolitis Obliterans Syndrome (BOS) progression in patients that have had a bilateral lung transplant. ARINA-1 is a nebulized therapy that has been shown to be safe and improve pulmonary function and quality of life in patients with a lung transplant.
CHAPEL HILL, N.C.--(BUSINESS WIRE)--Renovion, Inc., a clinical-stage pharmaceutical company focused on developing treatments for rare, chronic, and serious lung diseases with high unmet needs, announced today that they have received a Study May Proceed Letter from the U.S. Food and Drug Administration (FDA) for a Phase 2 clinical trial to investigate ARINA-1 in non-cystic fibrosis bronchiectasis (NCFBE). ARINA-1 is a nebulized therapy that thins mucus and enables mucus clearance from the lungs while decreasing pathological inflammation.
CHAPEL HILL, N.C.--(BUSINESS WIRE)--Renovion today announced that Dr. Martin “Marty” Zamora, MD, has joined Renovion as Chief Medical Officer. Dr. Zamora will lead the Phase 3 NDA-enabling clinical program in lung transplant and provide clinical expertise relative to the non-CF bronchiectasis (NCFBRE), non-tuberculosis mycobacteria pulmonary disease (NTM), and COPD programs that are also initiating this year.
CHAPEL HILL, N.C. & MIAMI--(BUSINESS WIRE)--Renovion and the COPD Foundation have announced the creation of a new partnership to accelerate the development of a novel therapy for the treatment of excessive airway mucus and inflammation in individuals with chronic obstructive pulmonary disease (COPD) and non-cystic fibrosis (CF) bronchiectasis. Phase 2 clinical trials are planned to begin in Q1 2022.
Renovion, Inc., a biopharmaceutical company on a mission to transform the treatment of chronic inflammatory lung diseases, announced the addition of Rich Mattingly to the Board of Directors. Renovion is developing ARINA-1 which is a nebulized therapy developed to improve mucus clearance and decrease inflammation in patients diagnosed with chronic lung disease.
CHAPEL HILL, N.C.--(BUSINESS WIRE)--Renovion, Inc., a biopharmaceutical company on a mission to transform the lives of patients with chronic lung diseases characterized by mucus and inflammation, announced publication of results from research conducted at The University of Alabama Birmingham. The research was funded in part by the Cystic Fibrosis Foundation and was conducted at The Rowe Lab at The Gregory Fleming James Cystic Fibrosis Research Center. Results of the research were published in the peer-reviewed American Journal of Respiratory Cell and Molecular Biology 1. The paper provides an overview of the impact of ARINA-1 on mucus transport and shows that the ARINA-1 moves mucus significantly better than currently available options in cystic fibrosis (CF).