Protagonist Therapeutics has dosed the first patient in a Phase II study evaluating novel hepcidin mimetic PTG-300 for the treatment of patients with polycythemia vera (PV).
NEWARK, Calif., Sept. 6, 2018 /PRNewswire/ -- Protagonist Therapeutics, Inc. (Nasdaq : PTGX ) today announced the receipt of a Phase 2 Small Business Innovation Research (SBIR) Grant from the National Heart, Lung and Blood Institute of the National Institutes of Health. This award, Number R44HL132702, provides up to $1.45 million over two years to support research aimed at developing the Company's novel hepcidin mimetic clinical drug for the potential treatment of chronic anemia and iron overload in rare blood disorders, including beta-thalassemia.
Protagonist Therapeutics, Inc., a company developing novel, orally-stable peptide therapeutics for gastrointestinal (GI) diseases, today announced that the company has initiated treatment of subjects with its lead drug candidate, PTG-100, in a Phase 1 clinical study. Protagonist is developing PTG-100, an orally-stable alpha-4-beta-7 integrin-specific peptide antagonist, as a potential treatment for patients with inflammatory bowel disease (IBD).