ALLSCHWIL, SWITZERLAND / ACCESSWIRE / December 30, 2021 / Polyphor AG (SIX:POLN) and EnBiotix Inc. today announced the closing of the merger of the two companies and the change of name of the combined company to Spexis AG. Pursuant to completion of the capital increase approved at the extraordinary general meeting of shareholders convened on October 28, 2021, Polyphor and EnBiotix, a privately held late clinical-stage rare disease company focused on products for rare, chronic respiratory diseases, have merged, via a transaction whereby Polyphor acquired 99.6% (with the remaining 0.4% expected to follow shortly) of the outstanding capital stock of EnBiotix in exchange for 35'150'961 shares of Polyphor common stock.
ALLSCHWIL, SWITZERLAND / ACCESSWIRE / September 1, 2021 / Polyphor (SIX:POLN) and EnBiotix Inc., a privately held late clinical-stage rare disease company currently focused on products for rare, chronic respiratory diseases, today announced that the companies have signed a merger agreement pursuant to which Polyphor acquires all of the outstanding capital stock of EnBiotix in exchange for shares of Polyphor common stock. The transaction is subject to a number of closing conditions, including approval by Polyphor and EnBiotix shareholders, satisfactory completion of due diligence and satisfactory assessment of tax consequences. Following closing, expected in Q4 2021, Polyphor will be renamed and is expected to trade under a new ticker symbol on the Swiss Stock Exchange.
EQS-Adhoc: Polyphor provides update on the future of the FORTRESS study of
ALLSCHWIL, Switzerland, June 28, 2021 (GLOBE NEWSWIRE) -- Polyphor AG (SIX: POLN), a research driven clinical stage, Swiss biopharmaceutical company committed to discovering and developing best-in-class molecules in oncology and antimicrobial resistance today announced that its global Phase III study, FORTRESS, evaluating balixafortide (POL6326) in combination with eribulin for the treatment of patients with HER2 negative, locally recurrent or metastatic breast cancer, did not meet its co-primary endpoint.
Swiss biotech Polyphor has seen its key cancer asset balixafortide fail a late-stage trial, leaving its future in the balance.
Backed by positive hamster data, Polyphor is now considering starting a phase 2 trial of its CXCR4 antagonist in COVID-19 patients.
ALLSCHWIL, Switzerland, Dec. 14, 2020 (GLOBE NEWSWIRE) -- Polyphor AG (SIX: POLN) announced today that the clinical trial independent Data Safety Monitoring Board (DSMB) has completed the third, pre-specified interim analysis, of safety outcomes based on a data cut off of 401 randomized patients in the Phase III pivotal study with balixafortide in HER2 negative, locally recurrent or metastatic breast cancer patients. The DSMB indicated that the Phase III clinical study should continue without modifications.
Polyphor picked up a $3.3 million award from the Cystic Fibrosis Foundation to develop an inhaled antibiotic for lung infections that are often deadly in people with cystic fibrosis.
ALLSCHWIL, Switzerland, Nov. 24, 2020 (GLOBE NEWSWIRE) -- Polyphor AG (SIX: POLN) today announced a funding agreement with the Cystic Fibrosis Foundation to advance clinical development of its novel class antibiotic, inhaled murepavadin, in cystic fibrosis (CF). Inhaled murepavadin is a highly potent and selective antibiotic against Pseudomonas aeruginosa, including multidrug resistant strains. CF is characterized by chronic bacterial infection and severe inflammation that lead to progressive deterioration in lung function.
Polyphor completes recruitment in Phase III trial of balixafortide in metastatic breast cancer