Lysogene Announces the Extension of Deadline for the Submission of Offers
Lysogene (FR0013233475 – LYS) (Paris:LYS), a phase 3 gene therapy platform Company targeting central nervous system (CNS) diseases, announces the conversion of the safeguard proceedings which has been in place since December 13, 2022 into reorganization proceedings.
Lysogene (FR0013233475 – LYS) (Paris:LYS), a phase 3 gene therapy platform Company targeting central nervous system (CNS) diseases, announces that it has requested, jointly with the judicial administrator, the conversion of safeguard proceedings, opened on December 13, into reorganization proceedings.
The Paris biotech requested the country’s government open what’s known as a “safeguard proceeding” on Tuesday, a legal maneuver amounting to a corporate restructuring overseen by a judge. A decision about how Lysogene shall move forward is expected next week, and the company has requested a stock halt while the French court deliberates.
On the heels of Lysogene’s lead gene therapy candidate flunking a phase 2/3 study, the French biotech has suspended trading of its shares and is seeking potential partnerships and investors in an effort to stay afloat.
Lysogene Provides Updates and Topline Results from Phase 2/3 AAVance Gene Therapy Clinical Study
With cash running out and a number of strategic options under consideration to stay afloat, Lysogene was banking on a clinical home run from its lead asset to woo investors. But new data presented by the company are anything but a splash.
Lysogene (FR0013233475 – LYS) (Paris:LYS), a phase 3 gene therapy platform Company targeting central nervous system (CNS) diseases, today announced topline results from the Phase 2/3 AAVance study evaluating LYS-SAF302, an investigational gene therapy for the treatment of MPS IIIA. In subjects enrolled at <30 months of age (ancillary cohort, n=6), a statistically significant improvement in cognitive development compared to natural history (NH) was observed at 24 months post-dosing. Subjects in this cohort also achieved key secondary efficacy criteria. The statistical analysis confirms previously communicated qualitative observations in the younger patient population, with consistency of effect across the outcome measures.
Lysogene (FR0013233475 – LYS), a phase 3 gene therapy platform Company targeting central nervous system (CNS) diseases, today announced that it will host a live webcast on Wednesday, November 23, 2022 at 1:30 pm CET to provide updates and topline results from the Phase 2/3 AAVance study evaluating LYS-SAF302, an investigational gene therapy for the treatment of MPS IIIA.
Lysogene (FR0013233475 – LYS), a phase 3 gene therapy platform company targeting central nervous system (CNS) diseases, provided updated clinical data from the ongoing AAVance phase 2/3 clinical trial with the investigational gene therapy LYS-SAF302 for the treatment of MPS IIIA (NCT03612869) during the 25th Annual Meeting of the ASGCT (American Society for Gene & Cell Therapy) in Washington, DC.