Amryt Announces Positive Top Line Results from Phase 3 Pediatric Trial of Lomitapide in HoFH DUBLIN, Ireland, and Boston MA, January 5, 2023, Amryt (Nasdaq: AMYT), a global, commercial-stage...
Amryt Pharma didn’t make much of a splash in May when it struck a deal to acquire Novelion’s Aegerion subsidiary, absorbing two commercial drugs and a US infrastructure in an all-stock deal. But now that the transaction has been wrapped, the Dublin-based company is ready to bring some renewed attention to it — as well as a fresh $60 million raise.
The US pharma is developing evinacumab to treat patients with homozygous familial hypercholesterolaemia (HoFH), with high levels of “bad” low-density lipoprotein (LDL) cholesterol despite treatment with other lipid-lowering therapies including maximum statin doses, and PCSK9 inhibitors.
Two years after nabbing a breakthrough therapy designation for evinacumab, Regeneron has a slate of stellar Phase III data to buttress its case for offering the antibody to patients whose LDL cholesterol are so out of control that they may need something even stronger than PCSK9 inhibitors.
Rare disease specialist Amryt Pharma plans to expand its rare disease portfolio with the acquisition of troubled Aegerion Pharmaceuticals, a division of Canada’s Novelion.
NHS England has okayed funding for Lojuxta, Amryt Pharma’s treatment for adults with an ultra-rare inherited condition causing extreme levels of cholesterol.
The high price of pharmaceuticals has become a constant topic of conversation in the U.S. As medical costs rise, consumers face greater financial uncertainty. And day after day, both the White House and Congress make promises that they will lower prescription costs to alleviate constituent concerns, but few changes have backed up their words.
A federal judge on Tuesday sentenced Aegerion Pharmaceuticals Inc for improperly marketing a cholesterol drug and ordered that some of the $40.1 million it agreed to pay to resolve a U.S. investigation go to the company’s victims.
Aegerion pleads guilty to US marketing violations
Novelion Therapeutics announced that subsidiary Aegerion Pharmaceuticals completed the first commercial shipment of Juxtapid (lomitapide) to a patient in Japan. In September 2016, Juxtapid was approved by Japan's Ministry of Health, Labor & Welfare (MHLW) for patients with homozygous familial hypercholesterolemia (HoFH).