In 2021, we made substantial progress in our projects to address unmet medical need in hematological cancers and inflammatory eye disorders. The fourth quarter in particular proved to be a busy period, with continued strong development with all the prioritized projects in our portfolio.
Lund, December 10, 2021 - Active Biotech (NASDAQ STOCKHOLM: nACTI) today announced that the first subject has been dosed in the phasenI clinical study of the newly developed eye-drop formulation of the ncompany’s candidate drug laquinimod.
Active Biotech AB has reached a manufacturing agreement with Famar Health Care Services Madrid SAU, a European provider of pharmaceutical manufacturing and development services. Famar will deliver clinical trial material of the newly developed eye-drop formulation of laquinimod.
Teva Pharmaceutical Industries has decided not to pursue development of laquinimod, and has returned rights to the drug back to Swedish group Active Biotech.
Laquinimod, an orally administered small molecule has primarily been developed as a potential treatment of neurodegenerative diseases such as multiple sclerosis (MS) and Huntington's disease (HD).
Teva has finally given up on laquinimod. The aryl hydrocarbon receptor activator was once hailed as a blockbuster heir to Copaxone but suffered a string of late-phase failures that dragged down Teva and its partner Active Biotech.
Teva has added yet another critical failure for laquinimod, which may finally be put on the chopping block.