STOCKHOLM, SWEDEN – September 14, 2022. Karolinska Development AB (Nasdaq Stockholm: KDEV) today announces that the portfolio company Umecrine Cognition has secured funding of SEK 41 million for the start of a Phase 2 study of the drug candidate golexanolone in primary biliary cholangitis, a condition that occurs when the bile ducts in the liver are slowly destroyed. The financing is being implemented as a convertible loan with attached share options. Karolinska Development is investing SEK 15 million as part of an investor consortium that includes, among others, AB Ility. The dilutive effect of the transaction will result in a negative earnings effect of SEK 49 million (7.7%) for Karolinska Development in the third quarter of 2022.
SAN DIEGO, June 10, 2022 (GLOBE NEWSWIRE) -- Oncternal Therapeutics, Inc. (Nasdaq: ONCT), a clinical-stage biopharmaceutical company focused on the development of novel oncology therapies, today...
Forendo’s lead therapy being developed to treat endometriosis is ready to enter Phase II trial.
STOCKHOLM, SWEDEN – November 3, 2021. Karolinska Development AB (Nasdaq Stockholm: KDEV) announces today that the portfolio company Umecrine Cognition will present new scientific results showing that the innate neurosteroid allopregnanolone plays an important role in the development of cognitive symptoms observed in patients with primary biliary cholangitis (PBC). Since Umecrine Cognition’s drug candidate golexanolone could potentially impact allopregnanolone the company has, based on the novel clinical results and other supportive data, initiated preparations for a Phase 2 clinical study in PBC. Umecrine Cognition will present the data at The Liver Meeting Digital ExperienceTM 2021, the premier Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), which takes place November 12-15.
TOCKHOLM, SWEDEN – October 27, 2021. Karolinska Development AB (Nasdaq Stockholm: KDEV) announces today that the portfolio company Dilafor, a drug development company focusing on the development of tafoxiparin for obstetric indications, has enrolled the first patient in a clinical Phase 2a study with tafoxiparin in pregnant women diagnosed with preeclampsia.
STOCKHOLM (Reuters) - American scientists David Julius and Ardem Patapoutian won the 2021 Nobel Prize for Medicine on Monday for the discovery of receptors in the skin that sense temperature and touch and could pave the way for new pain-killers.
STOCKHOLM (Reuters) - American scientists David Julius and Ardem Patapoutian won the 2021 Nobel Prize for Medicine on Monday for the discovery of receptors in the skin that sense temperature and touch and could pave the way for new pain-killers.
SOUTH SAN FRANCISCO, Calif., Sept. 28, 2021 (GLOBE NEWSWIRE) -- Fluidigm Corporation (NASDAQ:FLDM), an innovative biotechnology tools provider with a vision to improve life through comprehensive health insight, today announced a collaboration agreement with the Karolinska Institutet for research applications and product development utilizing CyTOF® XT, the fourth-generation platform based on Fluidigm’s pioneering CyTOF technology.
SOUTH SAN FRANCISCO, Calif., Sept. 28, 2021 (GLOBE NEWSWIRE) -- Fluidigm Corporation (NASDAQ:FLDM), an innovative biotechnology tools provider with a vision to improve life through comprehensive health insight, today announced a collaboration agreement with the Karolinska Institutet for research applications and product development utilizing CyTOF® XT, the fourth-generation platform based on Fluidigm’s pioneering CyTOF technology.
STOCKHOLM, SWEDEN – October 7, 2020. Karolinska Development AB (Nasdaq Stockholm: KDEV) announces today that the U.S. Food and Drug Administration (FDA) has accepted an Investigational New Drug (IND) application for its portfolio company Aprea Therapeutics’ novel drug candidate APR-548 to treat TP53 mutant myelodysplastic syndrome (MDS). APR-548 is a next-generation small molecule reactivator of mutant p53 that is being developed for oral administration.