US FDA grants Orphan Drug Designation for iOnctura's autotaxin cancer therapy
GENEVA and AMSTERDAM, Dec. 8, 2023 /PRNewswire/ -- iOnctura, a clinical-stage biotech developing selective cancer therapies against targets that play critical roles in multiple tumor survival pathways, today announces clinical results for roginolisib, a first-in-class oral allosteric modulator of PI3K?, presented at the ESMO Immuno-Oncology Congress 2023 in Geneva.
GENEVA andd AMSTERDAM, Nov. 3, 2023 /PRNewswire/ -- iOnctura, a clinical-stage biotech developing selective cancer therapies against targets that play critical roles in multiple tumor survival pathways, today announces abstract data to be presented at the 65th American Society of Hematology (ASH) Annual Meeting and Exposition, San Diego, California, from 9-12 December 2023.
iOnctura announces FDA clearance of IND application for roginolisib
AMSTERDAM and GENEVA, Oct. 19, 2023 /PRNewswire/ -- iOnctura, a clinical-stage biotech developing selective cancer therapies against targets that play critical roles in multiple tumor survival pathways, today announces publication of new research data in the peer-reviewed journal Cancer Research, that supports a strategy of combining autotaxin inhibitor IOA-289 with TGF-? pathway inhibitor IOA-359.
GENEVA and AMSTERDAM, June 1, 2023 /PRNewswire/ -- iOnctura, a clinical-stage biotech developing selective cancer therapies against targets that play critical roles in multiple tumor survival pathways, today announces that it will be presenting at leading scientific conferences throughout June 2023.
GENEVA and AMSTERDAM, May 3, 2023 /PRNewswire/ -- iOnctura, a clinical-stage biotech developing selective cancer therapies against targets that play critical roles in multiple tumor survival pathways, today announces it has exercised an exclusive option with Clavius Pharmaceuticals, adding the novel oral TGF-? pathway inhibitor, IOA-359, to its pipeline. The Company also announces it has, in collaboration with the University of Twente (UT), been awarded a grant from Health Holland and KWF (Dutch Cancer Society), reflecting the potential of IOA-359.
Clavius Pharmaceuticals and iOnctura have exercised an option to add the IOA-359 oral TGF-? pathway inhibitor to iOnctura’s pipeline.
GENEVA, Switzerland and AMSTERDAM,The Netherlands, March 28, 2023 /PRNewswire/ -- iOnctura, a clinical stage biotechnology company developing breakthrough therapies for patients suffering with cancer, today announces that the innovative medicine designation, the Innovation Passport, has been awarded for roginolisib, for the treatment of metastatic uveal melanoma by the Medicines & Healthcare products Regulatory Agency (MHRA).
The treatment is a first-in-class, non-ATP-competitive, allosteric modulator of PI3K?. It specifically prevents tumour proliferation while breaking immune tolerance among patients with solid and haematological tumours.