Earlier this week, Dublin, Ireland-based Inflazome announced that Roche (OTCQX:RHHBY) agreed to acquire it for €380M upfront plus milestones, signaling the biopharma giant's bullishness on an area generating substantial buzz called inflammasomes, innate immune system receptors and sensors that play key roles in a range of inflammatory disorders as well as metabolic and neurodegenerative diseases, including asthma, Parkinson's disease (PD), Alzheimer's disease (AD), inflammatory bowel disease, arthritis, cardiovascular disease, NASH, type 2 diabetes, multiple sclerosis and chronic kidney disease.
Roche has bought Inflazome for €380 million ($451 million) upfront to gain control of treatments for inflammatory diseases. The deal gives Roche full rights to a pipeline of oral NLRP3 inhibitors led by two clinical-phase drugs Inflazome is developing as treatments for Parkinson’s and other diseases.
DUBLIN & CAMBRIDGE, England - ( BUSINESS WIRE ) - Inflazome announces today that it has finalized a share purchase agreement with Roche (SIX: RO, ROG; OTCQX: RHHBY) under which Inflazome shareholders have received an initial payment of EUR 380 million, and are eligible to receive additional conditional payments subject to the satisfaction of predetermined criteria.
DUBLIN & CAMBRIDGE, England & BRISBANE, Australia--(BUSINESS WIRE)--Inflazome (inflazome.com), the pioneering inflammasome biotech company developing multiple drugs that stop harmful inflammation, today announces that it has been granted Orphan Drug Designation by the US Food and Drug Administration (FDA) for Inzomelid in the treatment of Cryopyrin-Associated Periodic Syndrome (CAPS).
DUBLIN & CAMBRIDGE, England & BRISBANE, Australia--(BUSINESS WIRE)--Inflazome (inflazome.com), the pioneering inflammasome biotech company developing multiple drugs that stop harmful inflammation, today announces that it has been granted Orphan Drug Designation by the US Food and Drug Administration (FDA) for Inzomelid in the treatment of Cryopyrin-Associated Periodic Syndrome (CAPS).
DUBLIN & CAMBRIDGE, England & BRISBANE, Australia--(BUSINESS WIRE)--Inflazome (inflazome.com), the pioneering inflammasome biotech company developing multiple drugs that stop harmful inflammation, today announces the successful completion of a Phase I study of Inzomelid, alongside positive results from a Cryopyrin-Associated Periodic Syndrome (CAPS) patient dosed with Inzomelid. CAPS is an autoinflammatory orphan disease driven by mutated NLRP3. The results support the progression of Inzomelid into Phase II clinical trials.