Although the current classification systems for patients with myelodysplastic syndromes (MDS) were able to identify groups of patients with similar outcomes, further refinement is needed to create more consistent criteria, according to findings from an international dataset analysis of the 2 classification systems presented by Rami Komrokji, MD, during the 2023 EHA Congress.
Merck’s Keytruda notched another positive set of data, this time in a rare cancer of the esophagus that sets up the company to receive full approval in this indication.
The authors of what they say is the largest and longest follow-up study comparing the trastuzumab biosimilar SB3 to the reference product (Herceptin) in HER2-positive breast cancer found “no clinically meaningful difference” between the biosimilar and the reference product.
Prestige BioPharma’s recent failure to get European approval for its Herceptin biosimilar could have resulted from the company’s changes in the manufacturing of the biosimilar during a phase-3 trial, the company said.
SINGAPORE--(BUSINESS WIRE)--Prestige BioPharma Limited (950210: KRX), a Singapore-based biopharmaceutical with operations in USA and South Korea, announced positive efficacy and safety results of the Phase 3 study for HD201 (TROIKA), a biosimilar to Herceptin® (trastuzumab), published in JAMA Oncology on March 4, 2022.
Opdivo added to chemotherapy before surgery in the so-called neoadjuvant setting lowered the risk of tumor recurrence, progression or death in patients with resectable stage IB to IIIA non-small cell lung cancer, BMS said Monday.
Cariprazine, the Allergan-turned-AbbVie drug for bipolar depression and schizophrenia, had a rocky road through clinical trials before its approvals. And as AbbVie attempts to further expand into major depressive disorder, it’s facing similar challenges.
An uptick in sales in the U.S. has yet to materialize for GSK’s Shingrix. But Jefferies isn't concerned about the ability of the vaccine to rebound.
Zymeworks presented encouraging early data on its HER2?targeted bispecific antibody—and a showdown with the incumbent Herceptin is up next.
MacroGenics’ oncology med Margenza is launching into the crowded HER2-positive breast cancer field. But the company has one advantage it can tout: The drug topped Roche's mainstay therapy Herceptin in a head-to-head trial.