HASSELT, Belgium, March 31, 2021 /PRNewswire/ -- Complix, a biopharmaceutical company developing a pipeline of transformative Alphabody therapeutics announces the publication in Science Advances of the results from a joint, multidisciplinary study with Belgian life sciences research Institute VIB and Ghent University. The proof-of-concept study demonstrates the potential of Cell-Penetrating Alphabodies™ (CPABs) to efficiently penetrate the cancer cell membrane, disrupt an intracellular protein-protein interface, and cause an anti-tumor effect upon in vivo administration in relevant xenograft models.
SEOUL, Nov. 23, 2020 /PRNewswire/ -- GemVax & KAEL Co., Ltd. a clinical stage company developing a novel peptide drug based on telomerase modification has released further positive data at the Korean Dementia Association's Fall Conference from a Phase II trial in Alzheimer's disease of lead candidate GV1001. Previously the company announced GV1001 was well tolerated and safe and the primary endpoint was achieved with notable improvements in Severe Impairment Battery (SIB) scores. The newly released data also shows a statistically significant improvement in the Neuropsychiatric Inventory (NPI) and an improvement trend in Alzheimer's Disease Cooperative Study-Activities of Daily living (ADCS-ADL). Based on these results, the company is now planning to submit a Phase III IND application.
SEOUL, Nov. 23, 2020 /PRNewswire/ -- GemVax & KAEL Co., Ltd. a clinical stage company developing a novel peptide drug based on telomerase modification has released further positive data at the Korean Dementia Association's Fall Conference from a Phase II trial in Alzheimer's disease of lead candidate GV1001. Previously the company announced GV1001 was well tolerated and safe and the primary endpoint was achieved with notable improvements in Severe Impairment Battery (SIB) scores. The newly released data also shows a statistically significant improvement in the Neuropsychiatric Inventory (NPI) and an improvement trend in Alzheimer's Disease Cooperative Study-Activities of Daily living (ADCS-ADL). Based on these results, the company is now planning to submit a Phase III IND application.
SEOUL, South Korea, Oct. 6, 2020 /PRNewswire/ -- GemVax & KAEL (GemVax) a clinical stage company developing novel immunotherapies based on telomerase modification today announced the decision to apply for an expanded access IND for its lead candidate GV1001 to include additional investigational groups in Alzheimer's, a disease the WHO estimates to affect 24 million people worldwide, in its clinical development program. This pivotal decision is based on an encouraging recent analysis of results from a Phase II trial completed last year in Korea and if granted would apply to a second Phase IIb trial in the US now planned for early 2021.