Ascletis’ subsidiary Gannex revealed that its non-alcoholic steatohepatitis (NASH) drug candidate significantly reduced average levels of liver fat in patients enrolled in a mid-stage trial, marking a positive milestone for the Chinese company.
Gannex Pharma has taken a peek at phase 2 data on its nonalcoholic steatohepatitis (NASH) prospect. The Ascletis Pharma subsidiary linked the THR? agonist to significant reductions in liver fat and pointed to findings that it sees providing an edge over Madrigal Pharmaceuticals and Viking Therapeutics.
China is expected to record the highest diagnosed prevalence of non-alcoholic fatty liver disease (NAFLD) in 2029, representing 44% of cases within the 16 major pharmaceutical markets (16MM). As a result, the number of clinical trials conducted in the country for this indication is gradually increasing, driven mostly by international pharmaceutical companies, but lacks substantial participation from domestic firms, says GlobalData, a leading data and analytics company.
Ascletis Pharma subsidiary Gannex Pharma has dosed the first participant in the US drug-drug interaction (DDI) study of ASC42 to treat primary biliary cholangitis (PBC).