Chugai Pharmaceutical Co., Ltd. announced that it concluded a license agreement with Roche for zilebesiran, an investigational RNAi therapeutic for hypertension created by Alnylam Pharmaceuticals, Inc. and currently under development by Roche and Alnylam.
Chugai Pharmaceutical Co., Ltd. announced that Japanese phase III study (NIHONBASHI study), evaluating the first and only bispecific antibody for the eye, Vabysmo (faricimab), for angioid streaks associated with neovascularization, met its primary endpoint, which demonstrated statistically significant and clinically meaningful vision improvement at 12 weeks. Vabysmo was generally well-tolerated and no new safety signal of this combination were observed.
Chugai: Piasky (crovalimab) for Paroxysmal Nocturnal Hemoglobinuria approved in Japan
An autoimmune disease drug from Roche and Chugai Pharmaceutical hit its main goal in a closely watched trial, but the results of the study, in a condition called myasthenia gravis, “did not reach our expectations,” the companies said Thursday.
Japan's Chugai Pharmaceutical has announced that crovalimab, a humanised complement inhibitor C5 monoclonal antibody, has been approved by the National Medical Products Administration (NMPA) of People’s Republic of China for treatment of adults and adolescents (12 years of age and above) with Paroxysmal nocturnal hemoglobinuria (PNH) not been previously treated with complement inhibitors.
Chugai Pharmaceutical Co., Ltd. announced that it filed regulatory applications with the Ministry of Health, Labour and Welfare for the anti-C5 antibody crovalimab for the treatment of paroxysmal nocturnal hemoglobinuria (PNH) on June 14, 2023.
Chugai Pharmaceutical Co., Ltd. announced that it has obtained approval from the Ministry of Health, Labour and Welfare (MHLW) on May 25, 2023, for FoundationOne Liquid CDx Cancer Genomic Profile to be used as a companion diagnostic for an anti-cancer agent/MET inhibitor, Tabrecta (generic name: capmatinib hydrochloride hydrate) of Novartis Pharma K.K. (Novartis), which is approved for the treatment of MET exon 14 skipping mutation-positive advanced and/or recurrent unresectable non-small cell lung cancer (NSCLC). With this approval, patients with advanced NSCLC who may be eligible for treatment with capmatinib can be identified through both tissue-based and liquid-based comprehensive genomic profiling (CGP) tests.
TOKYO and BOSTON, March 2, 2023 /PRNewswire/ -- Chugai Pharmaceutical Co., Ltd. (TOKYO: 4519) and Biofourmis, a global leader in technology-enabled care delivery, announced that they have entered into a new partnership agreement for the continued development and real-world use of digital solutions to objectively measure pain in patients with endometriosis. Endometriosis affects approximately 10%1 of all women of reproductive age and 70% of women with chronic pelvic pain, resulting in a reduced quality of life.2
Chugai Pharmaceutical Co., Ltd. and Towa Pharmaceutical Co., Ltd. announced that Towa launched Edirol tablets 0.5 µg/0.75 µg (generic name: eldecalcitol, hereafter, Edirol tablet) for an osteoporosis treatment (an active vitamin D3 preparation) upon the listing of the national health insurance (NHI) reimbursement price list. Edirol tablet was approved by the Ministry of Health, Labour and Welfare (MHLW) on August 15, 2022.
Chugai Pharmaceutical Co., Ltd. announced that the company celebrated the completion of its new research centre, Chugai Life Science Park Yokohama (Chugai LSP Yokohama).