As AstraZeneca fights to defend its aging two-drug inhaler Symbicort against generics, the company has a new approval to bolster its respiratory business.
LONDON, May 31, 2022 /PRNewswire/ -- Avillion LLP, a drug development company focused on the co-development and financing of pharmaceutical candidates from proof-of-concept through to regulatory approval, announces that the US Food and Drug Administration (FDA) has accepted for filing Avillion's New Drug Application (NDA) for AstraZeneca's PT027. The proposed indication is for the as-needed treatment or prevention of bronchoconstriction and for the prevention of exacerbations in patients with asthma 4 years of age and older.
WILMINGTON, Del.--(BUSINESS WIRE)--Full results from the positive MANDALA Phase III trial showed that PT027 (albuterol/budesonide) at two different strengths of budesonide, an inhaled corticosteroid (ICS), used as an as-needed rescue medicine, demonstrated a statistically significant reduction in the risk of a severe exacerbation versus albuterol rescue in patients with moderate to severe asthma.
UK biotech Avillion has reported positive mid-stage results with chronic psoriasis drug sonelokimab, which it is developing with Merck KGaA as an alternative to drugs like Novartis’ Cosentyx.
LONDON, April 23, 2021 /PRNewswire/ -- Avillion LLP, a drug development company focused on the co-development and financing of pharmaceutical candidates from proof-of-concept through to regulatory approval, announces that its positive Phase 2 trial of sonelokimab (M1095) in patients with chronic psoriasis has been published in the prestigious peer-reviewed medical journal The Lancet (Papp et al. ref. 1).
LONDON, Oct. 29, 2020 /PRNewswire/ -- Avillion LLP, a drug development company focused on the co-development and financing of pharmaceutical candidates from proof-of-concept through to regulatory approval, announces that positive results of its Phase 2 trial of sonelokinab (M1095), a novel anti-IL 17 A/F Nanobody, in patients with chronic psoriasis will be presented today in a Late-Breaking News session at EADV (European Academy of Dermatology and Venereology) 2020 Virtual Congress (29-31 October 2020). Top-line results from this study were first announced on 10 September 2020. The trial was conducted by Avillion under a 2017 co-development agreement with Merck KGaA Darmstadt, Germany and completed ahead of schedule.
LONDON, Oct. 29, 2020 /PRNewswire/ -- Avillion LLP, a drug development company focused on the co-development and financing of pharmaceutical candidates from proof-of-concept through to regulatory approval, announces that positive results of its Phase 2 trial of sonelokinab (M1095), a novel anti-IL 17 A/F Nanobody, in patients with chronic psoriasis will be presented today in a Late-Breaking News session at EADV (European Academy of Dermatology and Venereology) 2020 Virtual Congress (29-31 October 2020). Top-line results from this study were first announced on 10 September 2020. The trial was conducted by Avillion under a 2017 co-development agreement with Merck KGaA Darmstadt, Germany and completed ahead of schedule.
Abingworth lines up $315M to bet on a new generation of transatlantic biotechs