Swiss biopharmaceutical firm Debiopharm has started the dosing of the first patient in a Phase II proof-of-concept clinical trial of its antiviral alisporivir (Debio 025) for treating hospitalised Covid-19 patients.
LAUSANNE, Switzerland, Jan. 18, 2021 /PRNewswire/ -- Debiopharm (www.debiopharm.com), a Swiss biopharmaceutical company, announced today the first patient dosed in an investigator-initiated, randomized phase II, open-label clinical trial for its antiviral alisporivir (Debio 025). The study will be conducted by the AP-HP to assess the efficacy and safety of the cyclophilin inhibitor in the treatment of early stage, hospitalized COVID-19 patients not requiring medical ventilation nor exhibiting signs of acute respiratory distress syndrome.
Debiopharm International SA (Debiopharm), part of Debiopharm Group™, and Solid Biosciences, LLC, are proud to announce the start of preclinical studies of Alisporivir, in the rare disease Duchenne Muscular Dystrophy (DMD). The objective of the collaboration is to reinforce existing preclinical proof of concept data in additional DMD animal models. This preclinical work, fully funded by the Lausanne-based company, will then lead to Debiopharm initiating the clinical development of this new and promising therapeutic for DMD at its own expense in the near future.